Results 181 to 190 of about 10,524,108 (363)

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

Confounding fuels misinterpretation in human genetics. [PDF]

open access: yesProc Biol Sci
Benning JW   +4 more
europepmc   +1 more source

Atlas of the clinical genetics of human dilated cardiomyopathy

open access: hybrid, 2014
Jan Haas   +59 more
openalex   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

The potential impacts of human genetics on virus emergence. [PDF]

open access: yesProc Natl Acad Sci U S A
Langlois RA, Casanova JL.
europepmc   +1 more source

Development of a human genetics-guided priority score for 19,365 genes and 399 drug indications [PDF]

open access: green
Áine Duffy   +16 more
openalex   +1 more source

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