Results 261 to 270 of about 884,084 (316)

The Genetics of Human Longevity

Annals of the New York Academy of Sciences, 2006
Abstract:  Aging is due to a complex interaction of genetic, epigenetic, and environmental factors, but a strong genetic component appears to have an impact on survival to extreme ages. In order to identify “longevity genes” in humans, different strategies are now available.
CAPRI, MIRIAM, SALVIOLI, STEFANO, SEVINI, FEDERICA, VALENSIN, SILVANA, CELANI, LAURA, Monti D., Pawelec G., De Benedictis G., Gonos E. S., FRANCESCHI, CLAUDIO   +9 more
openaire   +2 more sources

Genetics of human cancer

Journal of Cellular Physiology, 1986
Study of hereditary cancer in humans has revealed new mechanisms in carcinogenesis. In particular, a new class of cancer gene, recessive in oncogenesis, accounts for dominantly transmitted predisposition to some cancers, and may play a primary role in the nonhereditary forms of most cancers.
openaire   +4 more sources

The genetics of human longevity

The American Journal of Medicine, 2004
Many of the genes that affect aging and longevity in model organisms, such as mice, fruit flies, and worms, have human homologs. This article reviews several genetic pathways that may extend lifespan through effects on aging, rather than through effects on diseases such as atherosclerosis or cancer.
Warren S, Browner, Arnold J, Kahn, Elad, Ziv, Alexander P, Reiner, Junko, Oshima, Richard M, Cawthon, Wen-Chi, Hsueh, Steven R, Cummings   +7 more
openaire   +2 more sources

The new human genetics

Environmental and Molecular Mutagenesis, 1995
This overview for the special issue of Environmental and Molecular Mutagenesis devoted to recent advances in human genetics relevant to mutagenesis briefly surveys the advances in the field. We present the evidence that trinucleotide repeat expansion can cause anticipation in human inherited disease.
R P, Erickson, S E, Lewis
openaire   +2 more sources