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Understanding the genetics of human infertility
Science, 2023Reproduction involves a wide range of biological processes, including organ formation and development, neuroendocrine regulation, hormone production, and meiosis and mitosis.
Qing Sang, P. Ray, Lei Wang
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The genetics of human obesity [PDF]
Nature Reviews Genetics, 2005 Obesity is an important cause of morbidity and mortality in developed countries, and is also becoming increasingly prevalent in the developing world. Although environmental factors are important, there is considerable evidence that genes also have a significant role in its pathogenesis.
Philippe Froguel +3 more
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From variant to function in human disease genetics
Science, 2021Description Over the next decade, the primary challenge in human genetics will be to understand the biological mechanisms by which genetic variants influence phenotypes, including disease risk.
T. Lappalainen, D. MacArthur
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Journal of Cellular Physiology, 1986
Study of hereditary cancer in humans has revealed new mechanisms in carcinogenesis. In particular, a new class of cancer gene, recessive in oncogenesis, accounts for dominantly transmitted predisposition to some cancers, and may play a primary role in the nonhereditary forms of most cancers.
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Study of hereditary cancer in humans has revealed new mechanisms in carcinogenesis. In particular, a new class of cancer gene, recessive in oncogenesis, accounts for dominantly transmitted predisposition to some cancers, and may play a primary role in the nonhereditary forms of most cancers.
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Current Opinion in Biotechnology, 1992
The introduction of new technology and increased effort from around the world is driving the completion of the human gene map. In parallel with the creation of the map, we are beginning to see the biomedical benefits that are a direct consequence of learning more about our own genome.
Peter N. Goodfellow, Louise Sefton
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The introduction of new technology and increased effort from around the world is driving the completion of the human gene map. In parallel with the creation of the map, we are beginning to see the biomedical benefits that are a direct consequence of learning more about our own genome.
Peter N. Goodfellow, Louise Sefton
openaire +4 more sources
The Genetics of Human Longevity
Annals of the New York Academy of Sciences, 2006Abstract: Aging is due to a complex interaction of genetic, epigenetic, and environmental factors, but a strong genetic component appears to have an impact on survival to extreme ages. In order to identify “longevity genes” in humans, different strategies are now available.
CAPRI, MIRIAM +9 more
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Taking race out of human genetics
Science, 2016Engaging a century-long debate about the role of race in science In the wake of the sequencing of the human genome in the early 2000s, genome pioneers and social scientists alike called for an end to the use of race as a variable in genetic research (1 ...
M. Yudell +3 more
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