Results 171 to 180 of about 2,044,942 (306)

SyMetrics: an integrated machine learning model for evaluating the pathogenicity of synonymous variants in the human genome. [PDF]

NAR Genom Bioinform
Bundalian L, Strnadová MS, Garten F, Horn S, Stenzel U, Popp D, Lemke JR, Biskup S, Schulte B, May P, Bösebeck F, Garten A, Thor D, Schulz A, Hentschel J, Kelso J, Schöneberg T, Le Duc D.   +17 more
europepmc   +1 more source

The human genome

Anales del Sistema Sanitario de Navarra, 2009
openaire   +3 more sources

Understanding bio‐based polymers: A study of origins, properties, biodegradation and their impact on health and the environment

FEBS Open Bio, EarlyView.
This review provides an overview of bio‐based polymer sources, their unique functional properties and their environmental impact, and addresses their role as sustainable alternatives. It discusses end‐of‐life options, including composting and anaerobic digestion for renewable energy.
Sabina Kolbl Repinc, Blaž Stres, Mirica Karlovits, Igor Karlovits, Petra Jerič, Ondrej Panák, Anja Verbič, Blaž Likozar, Uroš Novak   +8 more
wiley   +1 more source

Geometrically Encoded Positioning of Introns, Intergenic Segments, and Exons in the Human Genome. [PDF]

Adv Sci (Weinh)
Almassalha LM, MacQuarrie KL, Carignano M, Dunton CL, Gong R, Ibarra J, Carter LM, Li WS, Nap R, Dulai PS, Szleifer I, Backman V.   +11 more
europepmc   +1 more source

Sequencing the human genome [PDF]

Nature, 1986
J B, Walsh, J, Marks
openaire   +2 more sources

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

P170: Leveraging a genotype-first approach in All of Us cohort to describe prevalence and phenotypic spectrum of rare genetic disorders*

Genetics in Medicine Open
Katharine Chaillet, Jonas Ladenson, Anna Noreuil, Katherine Leopold, Robert Hubley, Shannon Haines, Joshua Denny, Huan Mo, Oleg Shchelochkov   +8 more
doaj   +1 more source

Identity rather than 3D position informs splicing of rare introns in the human genome. [PDF]

iScience
Springer SM, Fleck K, Girardini KN, Riccard SM, Erceg J, Kanadia RN.   +5 more
europepmc   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

The origin of mirror repeats in the human genome. [PDF]

Nucleic Acids Res
McGinty R, Lyskova A, Mirkin SM.
europepmc   +1 more source