Results 221 to 230 of about 913,987 (276)

Engineered Living Systems With Self‐Organizing Neural Networks: From Anatomy to Behavior and Gene Expression

Advanced Science, EarlyView.
Ectodermal tissue excised from Xenopus embryos self‐organizes into a three‐dimensional mucociliary organoid. Here, we generate a neural variant, termed neurobot, by implanting neural precursor cells. Neurobots develop mature neurons, adopt distinct morphologies, exhibit more complex motility, and respond differentially to neuroactive compounds. Imaging
Haleh Fotowat, Laurie O'Neill, Léo Pio‐Lopez, Megan M. Sperry, Patrick Erickson, Tiffany Lin, Michael Levin   +6 more
wiley   +1 more source

LMO7 Suppresses Tumor‐Associated Macrophage Phagocytosis of Tumor Cells Through Degradation of LRP1

Advanced Science, EarlyView.
LMO7 in tumor‐associated macrophages suppresses phagocytosis of tumor cells and limits cytotoxic T lymphocytes infiltration, fostering tumor progression. Mechanistically, LMO7 mediates the ubiquitination and degradation of the phagocytic receptor LRP1, impairing its ability to engulf tumor cells and driving macrophages toward an antitumor phenotype ...
Mengkai Li, Tao Wang, Yuwen Zhong, Zhiming Wang, Wei Li, Zejian Wang, Xinyi Yang, Yu Qiao, Jianfeng Xiang, Wei Gu, Zishu Wang, Lei Sun, Feng Qian   +12 more
wiley   +1 more source

Complete genome sequence of human papillomavirus type 45 identified from a cervical cancer patient in Bangladesh. [PDF]

Microbiol Resour Announc
Tusar MTT, Ara R, Farazi R, Roy CR, Mia R, Mozumder A, Das A, Piyel SH, Rahman MS, Bhuiyan MIU, Akter S, Islam SMRU, Ehsan MA, Ahmed MU, Hossain MG.   +14 more
europepmc   +1 more source

Cellular Snowballing: Cell Adhesion and Migration Drive the Self‐Assembly of Cell‐Microgel Biohybrid Spheroids

Advanced Science, EarlyView.
A new class of biohybrid spheroids is engineered through the self‐assembly of adherent cells and extracellular matrix‐mimetic hydrogel microparticles (microgels). By mimicking a snowballing effect, this approach enables scalable formation of porous, millimeter‐scale spheroids with enhanced cell viability and molecular diffusion.
Zaman Ataie, Sina Kheirabadi, Changhao Li, Aneesh Risbud, Aswathy Sebastian, Istvan Albert, Sulin Zhang, Amir Sheikhi   +7 more
wiley   +1 more source

Outbreaks of human respiratory syncytial virus in wild gorillas highlight the importance of prevention measures and integrated surveillance for risk mitigation. [PDF]

One Health
Jochum MJS, Singa-Niatou FS, Sanz C, Brogan S, Löhrich T, Neba TF, Leendertz FH, Morgan D, Patrono LV.   +8 more
europepmc   +1 more source

CDK4/6 Inhibition Induces CD8+ T Cell Antitumor Immunity via MIF‐Induced Functional Orchestration of Tumor‐Associated Macrophages

Advanced Science, EarlyView.
CDK4/6 inhibition promotes CD8+ T cell expansion through tumor‐macrophage crosstalk by activating HIF‐1α and enhancing MIF‐CD44/CD74 signaling. This reprograms TAMs to boost MHC‐I antigen presentation, and CDK4/6 inhibitor‐trained M1 TAM supernatant therapy synergizes with low‐dose PD‐1 blockade to restore antitumor immunity.
Lin He, Yuzhong Peng, Lat‐lun Leong, Jingbo Zhou, Dongyang Tang, Weilu Wang, Xiaoran Wu, Josh haipeng Lei, Yongqin Ye, Yangyang Feng, Yunfeng Qiao, Xiangpeng Chu, Di Mu, Qi Zhao, Tzuming Liu, Yan Chen, Paul Kwonghang Tam, Chu‐Xia Deng   +17 more
wiley   +1 more source

A Chromosome-level Assembly and Functional Genomic Resources for the Model Annelid Capitella teleta. [PDF]

Genome Biol Evol
Davies BE, Gonzalez P, Sur A, Wei J, Frankish T, Montagne J, Carrillo-Baltodano AM, Guynes K, Liang Y, Donnellan RD, Travis Moreland R, Singh S, Zhang S, Yu R, Wolfsberg TG, Meyer NP, Seaver EC, Baxevanis AD, Martín-Durán JM.   +18 more
europepmc   +1 more source

DDBJ update in 2025: system integration for global data-sharing including pathogen surveillance. [PDF]

Nucleic Acids Res
Ara T, Kodama Y, Fujisawa T, Kosuge T, Lee K, Mashima J, Ogasawara O, Tanizawa Y, Tanjo T, Nakamura Y, Arita M.   +10 more
europepmc   +1 more source

Draft genome sequence of <i>Escherichia coli</i> LA3 isolated from influent wastewater discharge of a tertiary-level hospital in Laguna, Philippines. [PDF]

Microbiol Resour Announc
Padon SDM, Cabuyao EMT, Cruz NJQ, Rodriguez KND, Dalmacio LMM, Bautista-Patacsil L, Beltran AB, Orbecido AH, Cornista JC.   +8 more
europepmc   +1 more source

Evolutionary dynamics and molecular adaptation of Rift Valley fever virus across human and non-human outbreaks in Africa

Omara IE, Juma J, Tshiabuila D, Dor G, Wilkinson E, Baxter C, Tegally H, Moir M, Oyola SO, de Oliveira T.   +9 more
europepmc   +1 more source