Results 61 to 70 of about 13,494,204 (297)
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Genomics and the Human Genome Project
, 2010 This OER consists of an instructional sheet produced by GENIE CETL in the Department of Genetics. By the end of this material you should have learnt about: The genome of an organism i.e.
GENIE CETL
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Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
, 2023 The Human Genome Project (HGP) is one of the most ambitious scientific endeavors of the 21st century, aiming to map and understand all the genes of the human species. Launched in 1990 and completed in 2003, this groundbreaking initiative involved international collaboration among scientists, geneticists, and researchers, spanning multiple countries and
Garg, HK, Vyas, Anuja
openaire +2 more sources
Justice and the human genome project
, 1994 The Human Genome Project is an expensive, ambitious, and controversial attempt to locate and map every one of the approximately 100,000 genes in the human body.
Murphy, Timothy F 1955- +3 more
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A novel NODAL variant in a young embolic stroke patient with visceral heterotaxy
BMC NeurologyBackground Ischemic stroke in young adults can be caused by a variety of etiologies including the monogenic disorders. Visceral heterotaxy is a condition caused by abnormal left–right determinations during embryonic development. We aimed to determine the
Kei Kaburagi +10 more
doaj +1 more source
Human microbiome, applied to clinical practice
Российский журнал гастроэнтерологии, гепатологии, колопроктологии, 2018 The aim of review. The Human microbiome project was designed for identification and characterization of set of human microorganisms as well as for studying the changes in the human health due to microbiome changes.
V. T. Ivashkin, K. V. Ivashkin
doaj +1 more source
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Entrepreneurial Experiments in Science Policy: Analizing the Human Genome Project [PDF]
We re-conceptualize the role of science policy makers, envisioning and illustrating their move from being simple investors in scientific projects to entrepreneurs who create the conditions for entrepreneurial experiments and initiate them.
Fiona E. Murray, Kenneth G. Huang
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