Results 101 to 110 of about 955,157 (297)
Managing Ambiguous Amphibians: Feral Cows, People, and Place in Ukraine’s Danube Delta [PDF]
This paper analyzes how a herd of feral cattle emerged in the core zone of Ukraine’s Danube Biosphere Reserve and why it still exists despite numerous challenges to the legality of its presence there.
Richardson, Tanya
core +1 more source
PD‐1 Inhibits CD4+ TRM‐Mediated cDC1 Mobilization via Suppressing JAML in Human NSCLC
CD4+ tissue‐resident memory T cells (TRMs) in non‐small cell lung cancer recruit conventional type 1 dendritic cells via XCL1‐XCR1 signaling, orchestrating antitumor immunity. The costimulatory molecule JAML is essential for this process. PD‐1 blockade restores JAML expression and cDC1 mobilization, while JAML agonists synergize with anti‐PD‐1 therapy,
Zheyu Shao +16 more
wiley +1 more source
A large‐scale, high‐resolution antimicrobial resistance (AMR) surveillance in Hong Kong community sewage combining short‐ and long‐read sequencing. The resistome profile is comprehensively characterized, and this upstream sampling strategy demonstrated superiority in reflecting the human gut resistome.
Jiahui Ding +11 more
wiley +1 more source
External and internal determinants of development [PDF]
As Rodrik, Subramanian, and Trebbi (2004) point out, factors that affect economic development can be classified using a two-tier approach. Based on a standard production function, inputs such as labor and physical and human capital directly affect per ...
Thomas Osang
core
A Novel Function of Nonadecanoic Acid in Regulating Glucose Homeostasis
This study identifies the odd‐chain fatty acid C19:0 as an endogenous ligand of GPR120 that promotes glucose homeostasis via Gαq signaling. In obesity, elevated palmitic acid suppresses endogenous C19:0 production through a miRNA–PPARα–HACL1 pathway, offering a promising direction for understanding the role of OCFAs in human health.
Yanting Hou +14 more
wiley +1 more source
This study presents the first telomere‐to‐telomere genomes and population resources for Diaporthe pathogens, uncovering the largest known fungal repertoire of secondary metabolite gene clusters. Structural variations and horizontal gene transfer drive cluster diversification, while specific rapidly evolving clusters control virulence, offering novel ...
Kainan Li +9 more
wiley +1 more source
GEOGRAPHY IN THE ORGANIZATIONAL STRUCTURE OF ACADEMIC INSTITUTIONS – SELECTED ISSUES
The goal of this article is to indicate the position that geography occupies within the organization structure of universities in given countries and to provide an overview of the research of research that predominated in the institutions and ...
Jerzy BANSKI
doaj +2 more sources
Human Geography and the hinterland: The case of Torsten Hägerstrand’s ‘belated’ recognition
Seeing Human Geography as a nexus of temporally oscillating concepts, this paper investigates the dissemination of scientific ideas with a focus on extra-scientific factors.
Brauer René, Dymitrow Mirek
doaj +1 more source
Economic Institutions and Human Well-Being: A Cross-National Analysis [PDF]
Economic institutions are widely thought to be important in enhancing human well-being. Other scholars emphasize geography in determining economic deprivation and development.
Seth W. Norton
core
MGM as a Large‐Scale Pretrained Foundation Model for Microbiome Analyses in Diverse Contexts
We present the Microbial General Model (MGM), a transformer‐based foundation model pretrained on over 260,000 microbiome samples. MGM learns contextualized microbial representations via self‐supervised language modeling, enabling robust transfer learning, cross‐regional generalization, keystone taxa discovery, and prompt‐guided generation of realistic,
Haohong Zhang +5 more
wiley +1 more source

