Results 191 to 200 of about 1,820,127 (391)

Engineered Living Systems With Self‐Organizing Neural Networks: From Anatomy to Behavior and Gene Expression

Advanced Science, EarlyView.
Ectodermal tissue excised from Xenopus embryos self‐organizes into a three‐dimensional mucociliary organoid. Here, we generate a neural variant, termed neurobot, by implanting neural precursor cells. Neurobots develop mature neurons, adopt distinct morphologies, exhibit more complex motility, and respond differentially to neuroactive compounds. Imaging
Haleh Fotowat, Laurie O'Neill, Léo Pio‐Lopez, Megan M. Sperry, Patrick Erickson, Tiffany Lin, Michael Levin   +6 more
wiley   +1 more source

Mapping the Functional Epitopes of Human Growth Hormone: Integrating Structural and Evolutionary Data with Clinical Variants. [PDF]

Curr Issues Mol Biol
Verma S, Pandey AV.
europepmc   +1 more source

Alterations of the genes involved in the PI3K and estrogen-receptor pathways influence outcome in human epidermal growth factor receptor 2-positive and hormone receptor-positive breast cancer patients treated with trastuzumab-containing neoadjuvant chemotherapy

, 2019
Kenichi Inoue, Junko Watanabe, Seishi Ogawa, Masaru Miyazaki, Masafumi Kurosumi, Higuchi, Toru, Yasuhiko Kaneko, Aiko Sato‐Otsubo, Fumio Kasai, Mamoru Takada, Hiroyuki Takei, Katsunori Tozuka, Masayuki Haruta   +12 more
openalex   +1 more source

SAT-LB15 24-Month Efficacy and Safety of Once Weekly and Every Other Week Administration of GX-H9, Hybrid FC-Fused Long-Acting Human Growth Hormone: A Phase 2 Study in Children With Growth Hormone Deficiency

, 2020
O. A. Malievskiy, Aryaev Mykola, Nataliya Zelinska, Е В Большова, Ганна Сергіївна Сенаторова, György Oroszlán, Julia Skorodok, Valentina Peterkova, Nataliya Chorna, Т.V. Sorokman, Seung Yang, Ji Eun Lee, Ágota Muzsnai, Jin Soon Hwang, Sang Yoon Lee, HyunJoo Son, SuJin Heo, Minkyu Heo, Yun Jung Choi, Young Chul Sung   +19 more
openalex   +1 more source

Dissolving microneedle patch for transdermal delivery of human growth hormone.

Small, 2011
Jeong Woo Lee, Seong-O Choi, E. Felner, M. Prausnitz   +3 more
semanticscholar   +1 more source

A Biomarker‐Driven Ovary–Endometrium Organ‐on‐a‐Chip Mimicking 3D Multicellular Complexity and Menstrual Cyclicity for Predicting Reproductive Toxicity

Advanced Science, EarlyView.
We present a dual‐organ, biomarker‐integrated ovaryendometrium organ‐on‐a‐chip that recapitulates 3D tissue complexity, menstrual cycle dynamics, and hormonal crosstalk. This platform enables real‐time, cell‐typespecific fluorescent readouts of reproductive toxicity using ANGPTL4 and SERPINB2 as early‐response reporters.
Soo‐Rim Kim, Eun‐kyung Min, Choon‐Mi Lee, Chan Hum Park, Byung‐Chul Oh, YunJae Jung, In‐Sun Hong   +6 more
wiley   +1 more source

Children with craniopharyngioma resection had better response to recombinant human growth hormone therapy than those with idiopathic short stature. [PDF]

Front Endocrinol (Lausanne)
Li T, Li C, Wang X, Nie M, Wu X, Mao J.
europepmc   +1 more source

Reduced Expression of Corticotropin-Releasing Hormone Receptor Type-1α in Human Preeclamptic and Growth-Restricted Placentas [PDF]

, 2003
Emmanouíl Karteris, Anastasia G. Goumenou, E. Koumantakis, Edward W. Hillhouse, Dimitris Grammatopoulos   +4 more
openalex   +1 more source

Human growth hormone abuse in male weightlifters.

American Journal on Addictions, 2011
B. P. Brennan, G. Kanayama, J. Hudson, H. Pope   +3 more
semanticscholar   +1 more source

CDK4/6 Inhibition Induces CD8+ T Cell Antitumor Immunity via MIF‐Induced Functional Orchestration of Tumor‐Associated Macrophages

Advanced Science, EarlyView.
CDK4/6 inhibition promotes CD8+ T cell expansion through tumor‐macrophage crosstalk by activating HIF‐1α and enhancing MIF‐CD44/CD74 signaling. This reprograms TAMs to boost MHC‐I antigen presentation, and CDK4/6 inhibitor‐trained M1 TAM supernatant therapy synergizes with low‐dose PD‐1 blockade to restore antitumor immunity.
Lin He, Yuzhong Peng, Lat‐lun Leong, Jingbo Zhou, Dongyang Tang, Weilu Wang, Xiaoran Wu, Josh haipeng Lei, Yongqin Ye, Yangyang Feng, Yunfeng Qiao, Xiangpeng Chu, Di Mu, Qi Zhao, Tzuming Liu, Yan Chen, Paul Kwonghang Tam, Chu‐Xia Deng   +17 more
wiley   +1 more source