Results 1 to 10 of about 12,361,119 (285)

Epileptic seizures temporally associated with recombinant human growth hormone therapy in children: A case series of three patients [PDF]

SAGE Open Medical Case Reports
We report three pediatric patients who developed epileptic seizures while receiving recombinant human growth hormone therapy. Case 1 was a 12-year-old girl with a history of febrile seizures and epilepsy whose seizures recurred after discontinuation of ...
Shigeru Nagaki, Minobu Shichiji, Hirokazu Oguni, Makiko Osawa   +3 more
doaj   +3 more sources

Recombinant human growth hormone in the treatment of Turner syndrome

Therapeutics and Clinical Risk Management, 2008
Bessie E SpiliotisDivision of Pediatric Endocrinology and Diabetes, Department of Pediatrics, University of Patras, School of Medicine, Patras, GreeceAbstract: Turner syndrome (TS) is a common chromosomal disorder in women that is associated with the ...
Bessie E Spiliotis
doaj   +5 more sources

Comparative pharmacokinetics and pharmacodynamics of a PEGylated recombinant human growth hormone and daily recombinant human growth hormone in growth hormone-deficient children

Drug Design, Development and Therapy, 2015
Ling Hou,1,* Zhi-hang Chen,2,* Dong Liu,3 Yuan-guo Cheng,2 Xiao-ping Luo1 1Department of Pediatrics, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 2Department of Pharmacy, Beijing Institute of ...
Hou L, Chen ZH, Liu D, Cheng YG, Luo XP
doaj   +5 more sources

Novel RAD50 variants lead to Nijmegen Breakage Syndrome–like disorder and unplanned recombinant human growth hormone treatment response [PDF]

Frontiers in Endocrinology
BackgroundHuman RAD50 gene mutations cause Nijmegen Breakage Syndrome-like disease, characterized by severe prenatal and postpartum growth retardation and microcephaly.
Yan Gong, MingYu Jiang, ShengNan Wu, Sheng Guo, YongFen Lyu   +4 more
doaj   +2 more sources

Growth Hormone Antibodies Formation in Patients Treated with Recombinant Human Growth Hormone [PDF]

International Journal of Immunopathology and Pharmacology, 2004
Human growth hormone (hGH) is normally produced by acidophilic cells of the anterior lobe of the pituitary gland. Recombinant DNA technology has made it possible to produce rhGH. There have been reports of immunological reactions in patients treated with rhGH.
G, Ahangari, M R, Ostadali, A, Rabani, J, Rashidian, M H, Sanati, M R, Zarindast   +5 more
exaly   +3 more sources

Effect of growth hormone to spinal growth and recombinant human growth hormone to scoliosis. [PDF]

Transl Pediatr
Growth hormone (GH) plays a key role in human growth and development. In addition to promoting height growth, GH affects bone metabolism, bone size, and bone mineral density (BMD) in children and adolescents by affecting bone formation and resorption. Among them, the effect of GH on spinal growth has been widely concerned.
Luo C, Liu S, Li Y, Wu Q, Liu Q, Peng D, Han S, Xu X, Wen J.   +8 more
europepmc   +3 more sources

The use of recombinant human growth hormone in patients with Mucopolysaccharidoses and growth hormone deficiency: a case series

Italian Journal of Pediatrics, 2019
Background The treatment with recombinant human growth hormone in patients affected by Mucopolysaccharidoses (MPS) is considered whenever a concurrent diagnosis of growth hormone deficiency is demonstrated. The short- and long-term effects of recombinant
A. Cattoni, S. Motta, N. Masera, S. Gasperini, A. Rovelli, R. Parini   +5 more
doaj   +3 more sources

Nutritional Counseling in Children with Growth Hormone Deficiency Treated with Recombinant Human Growth Hormone: Analysis of Growth Response Parameters [PDF]

Biomedicines
Background and Objectives: Growth failure is the main symptom of growth hormone deficiency (GHD) in children. The standard treatment for GHD is the administration of recombinant human growth hormone (rhGH).
Joanna Budzulak, Katarzyna Anna Majewska, Andrzej Kędzia   +2 more
doaj   +2 more sources

Comparison between long-acting pegylated and daily recombinant human growth hormone for pediatric growth hormone deficiency a systematic review [PDF]

Scientific Reports
This systematic review aims to summarize the therapeutic benefits and safety profile of long-acting PEGylated recombinant human growth hormone (PEG‑rhGH) compared with daily recombinant human growth hormone (DGH) in pediatric growth hormone deficiency ...
Jun Zhang, Song Guo, Tingting Wang, Qiuli Chen   +3 more
doaj   +2 more sources

Diagnosis and recombinant human growth hormone treatment of Wiedemann–Steiner syndrome: discovery of novel KMT2A variants and review of existing literature [PDF]

BMC Pediatrics
Purpose Wiedemann–Steiner syndrome (WDSTS) is an autosomal dominant disorder with broad and variable phenotypes including short stature. This study aims to determine the long-term effect of recombinant human growth hormone (rhGH) treatment on WDSTS and ...
Mengqin Wang, Jiaqian Hu, Zixia Zhang, Xi Wang, Shuxian Yuan, Yixuan Zhao, Yingxian Zhang, Haiyan Wei, Jiajia Chen, Yaodong Zhang, Yongxing Chen   +10 more
doaj   +2 more sources