Interaction of Human Chorionic Gonadotropin (hCG) and Asialo-hCG with Recombinant Human Thyrotropin Receptor. [PDF]
, 1994 hCG is a putative thyroid stimulator. The present studies were undertaken to examine its interaction and that of its desialylated variant asialo-hCG with recombinant human TSH (hTSH) receptor (hTSHr). To this end, we transfected a human thyroid carcinoma
Mann, K. +4 more
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Comparison of effectiveness of growth hormone therapy according to disease-causing genes in children with Noonan syndrome [PDF]
Korean Journal of Pediatrics, 2019 Purpose To analyze the growth response to growth hormone (GH) therapy in prepubertal patients with Noonan syndrome (NS) harboring different genetic mutations. Methods Twenty-three patients with prepubertal NS treated at Pusan National University Children’
Kyo Jin Jo +7 more
doaj +1 more source
The Separation of Recombinant Human Growth Hormone Variants by UHPLC [PDF]
Journal of Chromatographic Science, 2012 Reversed-phase ultra-high-performance liquid chromatography (RP-UHPLC) was used for the separation of recombinant human growth hormone (rhGH) variants. A bridged ethylene hybrid silica C18 column was used at 37°C. The composition and temperature of the mobile phase were optimized for the separation.
Göran, Karlsson +4 more
openaire +2 more sources
Human growth hormone produced with recombinant DNA technology [PDF]
BIO Web of ConferencesHormones affect the metabolism by stimulating the genetic apparatus of the cell, activating enzymes and changing the rate of enzymatic reactions. They increase the formation of informative ribonucleic acid, which determines the structure of the protein ...
Mustafakulov Muhammad +3 more
doaj +1 more source
Consensus guidelines for the diagnosis and treatment of adults with growth hormone deficiency: Summary statement of the growth hormone research society workshop on adult growth hormone deficiency [PDF]
, 1998 Based on the increasing body of evidence that adults with GH deficiency (somatotropin deficiency) have impaired health that improves with GH replacement, many countries have already approved the use of GH for replacement therapy in adults with GH ...
Growth Hormone Research Society Workshop on Adult Growth Hormone Deficiency +1 more
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Effect of Growth Hormone (hGH) Replacement Therapy on Physical Work Capacity and Cardiac and Pulmonary Function in Patients with hGH Deficiency Acquired in Adulthood. [PDF]
, 1995 The effects of 6 months of replacement therapy with recombinant human GH (hGH) on physical work capacity and cardiac structure and function were investigated in 20 patients with hGH deficiency of adult onset in a double blind, placebo-controlled trial ...
Schopohl, Jochen +5 more
core +1 more source
Immunofunctional assay of human growth hormone (hGH) in serum: A possible consensus for quantitative hGH measurement [PDF]
, 1996 Confirmation of the diagnosis of GH deficiency in adults and children involves provocative testing for human (h) GH. Different commercially available immunoassays yield largely discrepant results in the measurement of GH levels in human serum.
Strasburger, Christian J. +3 more
core +1 more source
Lipids in Health and Disease, 2018 Background Based on the sample of obese children with relative growth hormone deficiency (GHD), the objective of our study was to determine the effects of rhGH treatment on cardiovascular risk factors, including body mass index (BMI), lipid levels and ...
Shuang Liang, Jiang Xue, Guimei Li
doaj +1 more source
Transgenic fish and aquaculture [PDF]
, 1995 Transgenic fish species can be routinely produced by transferring foreign DNA into developing embryos via microinjection or electroporation. This technology offers an excellent opportunity for modifying or improving the genetic traits of commercially ...
Chen, Thomas T.
core +1 more source
Indian Journal of Endocrinology and Metabolism, 2019 Background: Growth hormone deficiency (GHD) remains the most common indication for use of recombinant human growth hormone (rhGH) therapy in clinical practice.
Monita Gahlot +5 more
doaj +1 more source