Results 11 to 20 of about 75,705 (253)

Novel RAD50 variants lead to Nijmegen Breakage Syndrome–like disorder and unplanned recombinant human growth hormone treatment response [PDF]

Frontiers in Endocrinology
BackgroundHuman RAD50 gene mutations cause Nijmegen Breakage Syndrome-like disease, characterized by severe prenatal and postpartum growth retardation and microcephaly.
Yan Gong, MingYu Jiang, ShengNan Wu, Sheng Guo, YongFen Lyu   +4 more
doaj   +2 more sources

Effect of growth hormone to spinal growth and recombinant human growth hormone to scoliosis [PDF]

Translational Pediatrics
Growth hormone (GH) plays a key role in human growth and development. In addition to promoting height growth, GH affects bone metabolism, bone size, and bone mineral density (BMD) in children and adolescents by affecting bone formation and resorption. Among them, the effect of GH on spinal growth has been widely concerned.
Luo, Cheng, Liu, Shuping, Li, Yanyan, Wu, Qiong, Liu, Qing, Peng, Danxia, Han, Shu, Xu, Xuan, Wen, Jie   +8 more
openaire   +3 more sources

Nutritional Counseling in Children with Growth Hormone Deficiency Treated with Recombinant Human Growth Hormone: Analysis of Growth Response Parameters [PDF]

Biomedicines
Background and Objectives: Growth failure is the main symptom of growth hormone deficiency (GHD) in children. The standard treatment for GHD is the administration of recombinant human growth hormone (rhGH).
Joanna Budzulak, Katarzyna Anna Majewska, Andrzej Kędzia   +2 more
doaj   +2 more sources

Comparison between long-acting pegylated and daily recombinant human growth hormone for pediatric growth hormone deficiency a systematic review [PDF]

Scientific Reports
This systematic review aims to summarize the therapeutic benefits and safety profile of long-acting PEGylated recombinant human growth hormone (PEG‑rhGH) compared with daily recombinant human growth hormone (DGH) in pediatric growth hormone deficiency ...
Jun Zhang, Song Guo, Tingting Wang, Qiuli Chen   +3 more
doaj   +2 more sources

Diagnosis and recombinant human growth hormone treatment of Wiedemann–Steiner syndrome: discovery of novel KMT2A variants and review of existing literature [PDF]

BMC Pediatrics
Purpose Wiedemann–Steiner syndrome (WDSTS) is an autosomal dominant disorder with broad and variable phenotypes including short stature. This study aims to determine the long-term effect of recombinant human growth hormone (rhGH) treatment on WDSTS and ...
Mengqin Wang, Jiaqian Hu, Zixia Zhang, Xi Wang, Shuxian Yuan, Yixuan Zhao, Yingxian Zhang, Haiyan Wei, Jiajia Chen, Yaodong Zhang, Yongxing Chen   +10 more
doaj   +2 more sources

Recombinant human growth hormone treatment of Floating-Harbor syndrome: a case report and literature review [PDF]

BMC Pediatrics
Background Floating Harbor syndrome (FHS) is a rare genetic disorder with over 100 reported cases worldwide and less than 30 treated with recombinant human growth hormone (rhGH).
Qing He, Yi Deng, Lei Xu, Zhe Xu, Yi Ding, Menghui Wu   +5 more
doaj   +2 more sources

Recombinant Human Growth Hormone: HIV-Related Lipodystrophy [PDF]

Hospital Pharmacy, 2014
This Hospital Pharmacy feature is extracted from Off-Label Drug Facts, a publication available from Wolters Kluwer Health. Off-Label Drug Facts is a practitioner-oriented resource for information about specific drug uses that are unapproved by the US Food and Drug Administration.
Joyce A, Generali, Dennis J, Cada
openaire   +2 more sources

Perspectives on long-acting growth hormone therapy in children and adults

Archives of Endocrinology and Metabolism, 2020
Growth hormone therapy with daily injections of recombinant human growth hormone has been available since 1985, and is shown to be safe and effective treatment for short stature in children and for adult growth hormone deficiency. In an effort to produce
Rayhan A. Lal, Andrew R. Hoffman
doaj   +1 more source

Assessment of Parental Satisfaction with the Treatment of Human Recombinant Growth Hormone in Children with Hypopituitarism

Pielęgniarstwo Neurologiczne i Neurochirurgiczne, 2021
Introduction. Growth depends on genetic, metabolic and also hormonal factors. Growth depends on health, the supply of nutrients and a properly functioning nervous system.
Lech Grzelak, Anna Wiśniewska
doaj   +1 more source

Case Report: Human Recombinant Growth Hormone Therapy in a DSH Cat Presented With Dwarfism

Frontiers in Veterinary Science, 2021
A 6-month-old kitten, male, domestic shorthair cat was presented with dwarfism, ocular and nasal discharge, and Ascaris infestation. Congenital hyposomatotropism was diagnosed on the basis of serum level of insulin-like growth factor-1 (IGF-I).
Martina Načeradská, Martina Načeradská, Kateřina Návojová Horáčková, Michaela Fridrichová   +3 more
doaj   +1 more source