Results 121 to 130 of about 232,985 (169)

Anti-Hair Loss Activity of Healthy Human Scalp-Derived <i>Staphylococcus capitis</i> KMH304 Ferment Filtrate in Human Hair-Follicle Dermal Papilla and Keratinocyte Cells. [PDF]

Microorganisms
Yoo HY, Gil TG, Kim NR, Lee HW, Choi S, Choi SJ, Park SH, Park BJ.   +7 more
europepmc   +1 more source

Soft Hypoxia‐Adaptive Bioelectronics Integrating PEDOT:PSS/Polydopamine/Enzyme Biocomposites for Closed‐Loop Therapeutics of Chronic Wounds

Advanced Science, EarlyView.
Hypoxia‐adaptive bioelectronics based on poly(3,4‐ethylenedioxythiophene):poly(styrene sulfonate) (PEDOT:PSS)/polydopamine (PDA)/enzyme biocomposites couple O2‐centric biosensing with embedded O2 therapy to address oxygen‐deficient chronic wounds. Local O2 provision restores enzyme‐based metabolite sensing, while catalase‐mediated oxygen generation and
Songrui Liu, Bowen Yang, Cao Qi, Zhijie Zhou, Haochen Zou, Anjum Qureshi, Xiao Zhao, Ting Li, Li Gao, Ye Tao, Gang Song, Pingqiang Cai, Zheng Li, Zhiyuan Liu, Dianpeng Qi, Ting Wang, Lianhui Wang   +16 more
wiley   +1 more source

Keratin adducts in human hair prove exposure to sulfur mustard in a real case of poisoning and indicate exposure to sesquimustard and O-lost in vitro. [PDF]

Arch Toxicol
John H, Schmeißer W, Dentzel M, Steinritz D, Sezigen S, Worek F.   +5 more
europepmc   +1 more source

A Novel Pak1 Activator Ameliorates ER Stress for HFpEF Therapy

Advanced Science, EarlyView.
Chronic metabolic stress is a major contributor to HFpEF progression. Under prolonged metabolic stress, Pak1 activity becomes impaired, contributing to disrupted ER proteostasis, cardiomyocyte apoptosis, fibrosis, and diastolic dysfunction. Mechanistically, Pak1 overexpression activates the ERK1/2–MNK1–eIF4E signaling axis, promotes translational ...
Honglin Xu, Hongyuan Zhang, Tayyiba Azam, Susanne S. Hille, Yingjuan Liu, Min Zi, Jiaqing Lang, He Yu, Yujia Cao, Bernard D. Keavney, Tamer M. A. Mohamed, Jessica M. Miller, Riham R. E. Abouleisa, Ming Xu, Elizabeth J. Cartwright, Oliver J. Müller, Ming Lei, Xin Wang   +17 more
wiley   +1 more source

Resident T cell activation leads to human hair follicle immune privilege loss <i>ex vivo</i>, which is prevented by the DHODH inhibitor farudodstat: relevance for alopecia areata. [PDF]

Front Med (Lausanne)
Piccini I, Rouillé T, Funk W, Jimenez F, Kaoukhov A, Firth C, Gilhar A, Edelkamp J, Cevikbas F, Bertolini M.   +9 more
europepmc   +1 more source

Functional Sex Reversal in Adult Gonochoristic Teleosts is Mediated by Ovarian Germline Stem Cell Plasticity and Somatic Cell Transdifferentiation

Advanced Science, EarlyView.
Oocytes play crucial roles in maintaining ovarian fate in adult gonochoristic fish. Targeted oocyte ablation with aromatase inhibition triggers the activation of surviving germline stem cells and the transdifferentiation of somatic cells from granoulosa/theca to Sertoli/Leydig lineages, inducing a complete and functional female‐to‐male sex reversal ...
Yang Yang, Liechao Yu, Wanchang Zhang, Gary Wessel, Ruiyi Chen, Weihua Hu, Dongdong Xu   +6 more
wiley   +1 more source

Raman Scattering Analysis of High Explosives on Human Hair: From Aromatic (TNT) to Aliphatic (RDX and PETN). [PDF]

Int J Mol Sci
Colón-González FM, Villarreal-Blanco MA, García-Tovar MP, Soler-Rodriguez PD, Serrano-Zayas TP, Vargas-Alers GL, Ocasio-Reyes E, García-Cruz LA, Castro-Suárez JR, Galán-Freyle NJ, Pacheco-Londoño LC, Centeno-Ortiz JA, Hernández-Rivera SP.   +12 more
europepmc   +1 more source

Targeting CXCR2 in Nociceptive Sensory Neurons Offers Novel Therapeutic Potentials for Postoperative Pain

Advanced Science, EarlyView.
Tissue incision induces CXCL5 release, which activates neuronal CXCR2 on incision‐innervating sensory neurons. Neuronal CXCR2 couples with TRPA1 to drive mechanical pain and engages p38 MAPK signaling to upregulate TRPV1 and promote heat pain. Targeted Cxcr2 knockdown relieves incisional pain while preserving CXCR2‐dependent neutrophil responses ...
Yushuang Pan, Peiyi Li, Yufeng Chen, Zishan Dong, Yuanyuan Li, Boyu Liu, Yan Tai, Chuan Wang, Jianqiao Fang, Chengyu Yin, Boyi Liu   +10 more
wiley   +1 more source

Ex vivo detection of SARS CoV 2 spike protein in human hair follicles and potential link to telogen effluvium. [PDF]

Sci Rep
Klingenstein S, Ruetalo N, Neckel PH, Kleger A, Schindler M, Liebau S, Klingenstein M.   +6 more
europepmc   +1 more source

An Innervated Human Skin Equivalent that Electrically Encodes Mechanical and Thermal Stimuli

Advanced Science, EarlyView.
An innervated human skin equivalent is integrated with high‐density microelectrode arrays to reveal how engineered free nerve ending–like structures translate touch and temperature into electrical codes. Mechanical indentation and thermal stimulation engage the engineered somatosensory circuitry and evoke distinct firing and waveform signatures ...
Daniele Bellantoni, Costantino Casale, Marika Sperduti, Nevio L. Tagliamonte, Giorgia Imparato, Loredana Zollo, Paolo A. Netti   +6 more
wiley   +1 more source