Results 201 to 210 of about 1,032,126 (309)

ZDHHC9‐Mediated Palmitoylation of ACSL4 Drives Ferroptosis in Diabetes Mellitus–Induced Erectile Dysfunction

Advanced Science, EarlyView.
ABSTRACT Diabetes mellitus‐induced erectile dysfunction (DMED) is a highly prevalent complication among diabetic patients; however, its underlying pathogenic mechanisms remain incompletely understood. Metabolic disorder is a hallmark of diabetes, yet its precise contribution to DMED progression is not well defined.
Wanyang Guo, Ming Xiao, Mengjun Huang, Dongzi Peng, Ruijiang Zeng, Ruilin Liu, Yuanqiao Zhao, Zhihan Ouyang, Yulong Hong, Zexian Ding, Zhuo Xing, Hao Su, Jinxiang Wang, Wenjun Mao, Xin Jin   +14 more
wiley   +1 more source

Core-shell Particle Embedding into Human Hair: A Novel Approach for Surface Modification and Long-Lasting Hair Coloration. [PDF]

ACS Omega
Fujimoto K, Nishimura M, Fukui Y.
europepmc   +1 more source

GPCRs in CAR‐T Cell Immunotherapy: Expanding the Target Landscape and Enhancing Therapeutic Efficacy

Advanced Science, EarlyView.
Chimeric antigen receptor T cell therapy faces dual challenges of target scarcity and an immunosuppressive microenvironment in solid tumors. This review highlights how G protein‐coupled receptors can serve as both novel targets to expand the therapeutic scope and functional modules to enhance CAR‐T cell efficacy.
Zhuoqun Liu, Yuchen Xiao, Yamin Zhao, Lihe Dai, David J.H. Shih, Shikang Liang, Honglei Tian, Liu Liu, Feng Tian, Bing Liu, Lei Chang, Chao Zhang   +11 more
wiley   +1 more source

Optimization of concrete with human hair using experimental study and artificial neural network via response surface methodology and ANOVA. [PDF]

Sci Rep
Yıldızel SA, Karalar M, Aksoylu C, Althaqafi E, Beskopylny AN, Stel'makh SA, Shcherban' EM, Umiye OA, Özkılıç YO.   +8 more
europepmc   +1 more source

Thermally Degradable Biocompatible Hydrogel as Transient Encapsulation Coating for Implantable Sensors

Advanced Science, EarlyView.
A biocompatible hydrogel coating with tissue‐like mechanics and reversible dissolution triggered by a mild, physiologically compatible temperature drop (≈37°C → ≈25°C) was developed for the transient encapsulation of implantable devices. The physically crosslinked methylcellulose, polyethylene glycol and polyacrilic acid (MC/PEG/PAA) hydrogel ...
Francesca Persano, Eleonora Vandini, Eleonora Daini, Antonietta Vilella, Daniela Giuliani, Leonardo Lamanna, Marco Friuli, Christian Demitri, Laura Pecoraro, Amilcare Barca, Tiziano Verri, Cosimino Malitesta, Martina Corsi, Giuseppe Barillaro, Elisabetta Mazzotta   +14 more
wiley   +1 more source

Morphometric prediction of mesenchymal stromal cell-like immunosuppressive capacity of human hair follicle dermal sheath cup cells: an implication for regenerative medicine in hair loss diseases. [PDF]

Stem Cell Res Ther
Tsuji H, Lin HY, Kinoshita S, Jinguji H, Nakazawa Y, Ogo M, Ohyama M.   +6 more
europepmc   +1 more source

SKOOTS: Skeleton‐Oriented Object Segmentation for Mitochondria in High‐Resolution Cochlear EM Datasets

Advanced Science, EarlyView.
Skeleton‐oriented object segmentation (SKOOTS) introduces a new strategy for 3D mitochondrial instance segmentation by predicting explicit skeletons rather than relying on boundary cues. This approach enables robust analysis of densely packed organelles in large FIB‐SEM datasets.
Christopher J. Buswinka, Richard T. Osgood, Hidetomi Nitta, Artur A. Indzhykulian   +3 more
wiley   +1 more source

Ultrasensitive Direct Chemical Analysis of Human Hair Using Proton Transfer Reaction Time-of-Flight Mass Spectrometry (PTR-TOF-MS) for Nontargeted Exposure Profiling. [PDF]

Chem Res Toxicol
Neville AC, Jarma DA, Blomdahl DC, Lin CH, Kinney KA, Misztal PK.   +5 more
europepmc   +1 more source

Discovery of an Adaptive Neuroimmune Response Driving Itch and Fast Tick Removal with Implications for Preventing Pathogen Transmission

Advanced Science, EarlyView.
Itch‐induced tick removal (IITR): An acquired neuroimmune mechanism, itch‐induced tick removal, develops after repeated tick exposure, mobilizing T cells and macrophages at the tick bite site to trigger a rapid scratching response that facilitates timely tick removal within a critical window that precedes the transmission of many tick‐borne pathogens ...
Johannes S. P. Doehl, Tiago D. Serafim, Serena Doh, Charles S. Grugan, Eva Iniguez, Luana Rogerio, Ronja Frigard, Ranadhir Dey, Pedro Cecilio, Xinglong Gu, Pang‐Yen Tseng, Aline da Silva Moreira, Mahnaz Minai, James Oristian, Hans Ackerman, Steven Brooks, Caroline Percopo, Siu‐Ping Ng, Derron A. Alves, Lucas Tirloni, Jennifer M. Anderson, Adriana Marques, Fabiano Oliveira, Shaden Kamhawi, Daniel E. Sonenshine, José M. C. Ribeiro, Mark Hoon, Jesus G. Valenzuela   +27 more
wiley   +1 more source

Protective Effects of Korean Red Ginseng Against Oxidative Stress-Induced Damage in Human Hair. [PDF]

Ann Dermatol
Jung SW, Pi LQ, Jeon JJ, Kim YH, Lee S, Lee WS.   +5 more
europepmc   +1 more source