Results 21 to 30 of about 5,202,625 (193)

Ethylenebisdithiocarbamates and ethylenethiourea: possible human health hazards. [PDF]

open access: yes, 1995
Humans are exposed to ethylenebisdithiocarbamates (EBDCs) from environmental sources. Exposure to EBDCs is chronic for workers in a variety of industries, where EBDCs are used for their properties as slimicides, vulcanization accelerators, antioxidants ...
Bindoula, G, Hoffman, JR, Houeto, P
core   +2 more sources

Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia

open access: yesFEBS Letters, EarlyView.
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley   +1 more source

A Vision of Health and Human Rights for the 21st Century: A Continuing Discussion with Stephen P. Marks [PDF]

open access: yes, 2001
Professor Marks offers an eloquent vision of health and human rights in the 21st Century. As the Director of the Francois-Xavier Bagnoud Center for Health and Human Rights, Professor Marks ably carries the torch that Jonathan Mann lit in the field until ...
Gostin, Lawrence O.
core   +2 more sources

Making tau amyloid models in vitro: a crucial and underestimated challenge

open access: yesFEBS Letters, EarlyView.
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley   +1 more source

Human Rights in Global Health Governance [PDF]

open access: yes, 2018
Human rights frame global health governance. In codifying a normative foundation for global governance in the aftermath of World War II, states came together under the auspices of an emergent United Nations (UN) to develop human rights under ...
Gostin, Lawrence O.   +2 more
core   +1 more source

The intracellular domain of TLR2 is capable of high‐affinity Zn binding: possible outcomes for the receptor activation

open access: yesFEBS Letters, EarlyView.
Toll‐like receptors (TLRs) are important in the innate immune system. This study explores the zinc‐binding ability of the TLR2 TIR domain (TLR2TIR). We found that TLR2TIR binds zinc with nanomolar affinity through its cysteine residues. Two of them, C673 and C713, are vital for receptor activation, indicating that zinc may play a role in initiating ...
Vladislav A. Lushpa   +8 more
wiley   +1 more source

Depleted Uranium and Human Health [PDF]

open access: yes, 2005
Persistent public anxiety about the use of depleted uranium munitions since the early 1990s has been underpinned by claims of serious health consequences for both veterans and exposed civilians, alike. Whatever grounds there may have seemed to be in the
Smith, Ron C.
core   +1 more source

The power of microRNA regulation—insights into immunity and metabolism

open access: yesFEBS Letters, EarlyView.
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto   +2 more
wiley   +1 more source

Grain legumes and human health [PDF]

open access: yes, 2009
Since early civilisation in different continents, grain legumes have been a part of balanced diets together with cereals. In general the seeds from those two plant families give together a good source of essential amino acids and may have given an ...
Enneking, Dirk   +4 more
core   +1 more source

Bad Water 2009: The Impact on Human Health in the Chesapeake Bay Region [PDF]

open access: yes, 2009
The report links pollution to human health risks and calls on the federal Environmental Protection Agency (EPA) to act now to reduce that pollution and the potential threats to human ...
Tom Pelton
core   +1 more source

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