Results 171 to 180 of about 18,164,503 (309)

Human Health Risk Assessment During the Synthesis and Application of Engineered Nanomaterials in a Controlled Laboratory Environment. [PDF]

Toxics
Letsoalo M, Masekameni MD, Andraos C, Gulumian M.   +3 more
europepmc   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

Spatiotemporal Dynamics and Human Health Risk Assessment of Potentially Toxic Elements in Global Urban Soils: A Systematic Meta-Analysis. [PDF]

Toxics
Cui J, Lu J, Lai Y, Wei Q, Zhao X.
europepmc   +1 more source

MERCURY EXPOSURE IN COSMETICS AND HUMAN HEALTH RISK

FARMACIA, 2023
Birsan, Magdalena, Stan, Catalina, Mielcarek, Konrad, Nowakowski, Patryk, Katarzyna Socha, Scripcariu, Sadiye-Ioana, Antonoaea, Paula, Vlad, Robert, Todoran, Nicoleta, Ciurba, Adriana   +9 more
openaire   +1 more source

THE INFLUENCE OF SALMONELLA IN PIGS PRE-HARVEST ON SALMONELLA HUMAN HEALTH COSTS AND RISK FROM PORK [PDF]

Salmonellosis in people is a costly disease, much of it occurring because of food associated exposure. We develop a farm-to-fork model which estimates the pork associated Salmonella risk and human health costs.
Miller, Gay Y., Barber, David A., Liu, Xuanli, McNamara, Paul E.   +3 more
core   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Digestate biochar effects on soil Pb bioaccessibility, crop Pb concentrations, and human health risk in urban vegetable agroecosystems. [PDF]

Environ Geochem Health
Newell J, Doherty R, Lyons G, Cox SF.
europepmc   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Toxic Substances in Plastics, Micro- and Nanoplastics: Utilizing ATSDR's Plastics-Related Toxicological Profile Tool and Mixtures Framework for Human Health Risk Assessment. [PDF]

Toxics
Muianga CV, Zarus GM, Stallings K, Casillas G, Shoeb M, Gehle K, Mumtaz MM, Reh CM.   +7 more
europepmc   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source