Results 191 to 200 of about 6,269,925 (357)
The problem with which human ecology confronts medical librarians is that of inherent complexity combined with vagueness of definition and thought, associated with the risk of dispersing effort and funds ineffectually and too widely. Much of this paper is concerned with explaining why ecology must primarily be concerned with the "physiology of ...
openaire +1 more source
Editorial: Translating soil science to improve human health
G. M. Hettiarachchi +4 more
openaire +2 more sources
USSR Space Life Sciences Digest, issue 6 [PDF]
This is the sixth issue of NASA's USSR Space Life Sciences Digest. It contains abstracts of 54 papers recently published in Russian language periodicals and bound collections and of 10 new Soviet monographs.
Hooke, L. R. +3 more
core +1 more source
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
The age of authenticity anxiety: Artificial intelligence and emerging questions for mental health. [PDF]
Brown AD.
europepmc +1 more source
Goals for development : history, prospects and costs [PDF]
The Millennium Development Goals set quantitative targets for poverty reduction and improvements in health, education, gender equality, the environment, and other aspects of human welfare.
Devarajan, Shantayanan +2 more
core
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Developing Scenario-Based Strategies for Health, Climate, and Environmental Preparedness: The One Health, One Earth Approach. [PDF]
Abadi AM +26 more
europepmc +1 more source

