Results 191 to 200 of about 30,135,302 (286)

Public Perceptions and Determinants of Preference for Robotic-Assisted Surgery in the United Arab Emirates: Cross-Sectional Study. [PDF]

JMIR Hum Factors
Elhadi YAM, Abdullahi AS, Alblooshi AM, Alhosani A, Al Khalidi A, Saleem M, Alrashdi SRM, Aljaberi RS, Rahma AT.   +8 more
europepmc   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

Landscape Analysis of Existing Policies, Laws and Regulations on Antimicrobial Stewardship in 10 Low- and Middle-Income Countries. [PDF]

Antibiotics (Basel)
Waswa JP, Joshi MP, Kiggundu R, Kakooza F, Byonanebye DM, Ayebare RR, Kikule K, Kasujja H, Konduri N, Nfor E.   +9 more
europepmc   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Self-Reported Dietary Carotenoid Intake and Skin Carotenoid Score Status in a Geographically Diverse U.S. Sample. [PDF]

Nutrients
Hasnin S, Sisson SB, Jilcott Pitts S, Dvorak JD, Swindle TM, Casperson SL, Braun A, Baldwin J, Lynn E, Stage VC.   +9 more
europepmc   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Space biology as a catalyst for the next biotech and longevity revolution. [PDF]

Exp Physiol
Kern C, Cook M, Reynolds E, Ashar A, Siew K, Johnson IRD, Grzesiak N, Jopling L, Christian M, Libera R, Gartner I, Ferreira MJS, Salem AK, Birch W, Dhanji N, Cullen DC, Sampaio JM, Oliveira D, Catchpole S, Richardson R, Milašius D, Bailey DM.   +21 more
europepmc   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Trypanosoma cruzi infection in pregnancy: New approaches to address the diagnosis and follow-up of women and newborns. [PDF]

PLoS Negl Trop Dis
Carlier Y, Alger J, Dumonteil E, Herrera C, Schijman AG, Buekens P.   +5 more
europepmc   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source