Results 111 to 120 of about 16,898,411 (216)

Severe Pediatric MOGAD‐Associated ADEM With Persistent Neurological Morbidity and Later‐Onset Epilepsy of Uncertain Etiology: A Case Report

open access: yesClinical Case Reports, Volume 14, Issue 10, October 2026.
ABSTRACT This report describes a 7‐year‐old boy with MOGAD presenting as severe ADEM with fever, encephalopathy, seizures, markedly elevated intracranial pressure, diffuse multifocal MRI abnormalities, and serum MOG‐IgG positivity. He required intravenous corticosteroids, plasma exchange, IVIG, and tocilizumab, followed by rehabilitation and ...
Desiree‐Anne Ramsaran   +2 more
wiley   +1 more source

Proteomic analysis of pathogenic and attenuated alcelaphine herpesvirus 1 [PDF]

open access: yes, 2008
The gammaherpesvirus alcelaphine herpesvirus 1 (AlHV-1) causes malignant catarrhal fever in susceptible ungulates but infects its natural host, wildebeest, without obvious clinical signs.
Stewart, James P.   +5 more
core  

Benzimidazole Analogs Inhibit Human Herpesvirus 6

open access: yes, 2011
Several benzimidazole nucleoside analogs, including 1H-β- d -ribofuranosyl-2-bromo-5,6-dichlorobenzimidazole (BDCRB) and 1H-β- l -ribofuranosyl-2-isopropylamino-5,6-dichlorobenzimidazole (maribavir [MBV ...
Mark N. Prichard   +6 more
core   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, Volume 600, Issue 17, Page 2526-2546, September 2026.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

HUMAN HERPESVIRUS-6 MENINGITIS IN THREE HEALTHY CHILDREN

open access: yes, 2021
Background: Human herpesvirus-6 is recognized as a central nervous system pathogen andencephalitis is associated with high mortality and morbidity, especially in immunocompromised patients.We describe three previously healthy children with human ...
Kara, Yalçın   +4 more
core  

Radiotherapy Enhances the Oncolytic Efficacy of the Novel Oncolytic Herpesvirus VG161 and Amplifies Its Antitumor Immunity in Breast Cancer

open access: yesAdvanced Science, Volume 13, Issue 52, 18 September 2026.
RT promotes VG161 replication in BC and its immunostimulatory transgenes expression, which is mediated by the upregulation of GADD34 and HVEM caused by RT. The combination therapy with VG161 and RT increases the abundances of tumor‐infiltrating lymphocytes and elicits potent systemic antitumor immunity, thereby effectively inhibiting local tumors and ...
Lijuan Lyu   +13 more
wiley   +1 more source

Human Herpesvirus 6

open access: yes, 2008
Human herpesvirus 6 (HHV-6)เป็นสมาชิกใหม่ของ family Herpesviridae การติดเชื้อครังแรกทำให้เกิดโรคไข้ออกผื่นชื่อ exanthem subitum (roseola infantum)ในเด็กเล็กที่มีอายุระหว่าง 6 -24 เดือน หลังการติดเชื้อครั้งแรก HHV-6 จะทำให้เกิดการติดเช ...
ผู้มีโชคชัย, วรรณา
core  

p300 Degradation by the p53‐SIAH1 Axis Relieves TBK1 Acetylation to Enhance Innate Antiviral Immunity

open access: yesAdvanced Science, Volume 13, Issue 50, 7 September 2026.
This study identifies p300 as the acetyltransferase that acetylates TBK1 and inhibits its phosphorylation. Activation of the p53‐SIAH1 axis by immune response downregulates p300 expression to sustain innate antiviral immunity. Conditional p300 knockout in alveolar epithelial cells in vivo promotes antiviral responses and suppresses virus replication ...
Huidi Yu   +6 more
wiley   +1 more source

Human herpesvirus 6 infection mimicking measles: two pediatric cases

open access: yesThe Turkish Journal of Pediatrics, 2015
Measles is a highly contagious viral infection associated with clinical symptoms such as fever, cough, conjunctivitis, coryza, eruption and increased serum immunoglobulin M (IgM) antibodies.
Masahide Goto   +5 more
doaj  

Chromosomal Integration of HHV-6 in a Preterm Neonate: A Rare Case of Hyperleukocytosis and Clinical Implications

open access: yesPediatric Reports
Leukocytosis in neonates can occur because of infectious, inflammatory, malignant, or physiological processes. Hyperleukocytosis is defined as a total leukocyte count (TLC) exceeding 100,000 per mm3, warranting immediate evaluation.
Palanikumar Balasundaram, Mohamed Sakr
doaj   +1 more source

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