Results 121 to 130 of about 16,898,411 (216)
This study identifies RNA‐binding protein RBM25 as a broad‐spectrum antiviral factor acting independently of type I interferon. It blocks viral entry by suppressing GTPase Rab22a via the RC3H1‐mediated destabilization of Rab22a mRNA. Viral downregulation of RBM25 enhances GTPase Rab22a expression and viral entry, revealing an unreported post ...
Yingying Ding +13 more
wiley +1 more source
Human herpesvirus 6 and human herpesvirus 7 in chronic fatigue syndrome
We analyzed lymphocytes of patients with chronic fatigue syndrome (CFS) for the presence of human herpesvirus 6 (HHV-6) and HHV-7 DNA. HHV-7 was present in over 80% of CFS patients and healthy controls, while the prevalence of HHV-6 variant A ...
CASSAI E. +11 more
core
A three‐tier livestock multi‐omics framework resolves four typical analytical pitfalls. Moving from statistical association through machine learning preprocessing to triple‐modal causal inference, it converts omics results into genomic selection and gene editing strategies to achieve One Health, underpinned by multi‐omics data, multimodal sequencing ...
Jiying Wen +5 more
wiley +1 more source
The Significance of cGAS‐STING Signaling in Response to Oncogenic Viruses
ABSTRACT The cyclic GMP‐AMP synthase (cGAS)‐stimulator of interferon genes (STING) signaling pathway, as a key DNA sensor, plays a significant role in the regulation of innate immune responses. This pathway can be activated by sensing abnormal DNA, and is of great significance for resisting the invasion of pathogenic microorganisms and maintaining ...
Limei Guo +4 more
wiley +1 more source
Beyond the Rash: Simultaneous Bilateral Facial Nerve Palsy Following Childhood Varicella Infection
ABSTRACT Bilateral facial nerve palsy is a rare neurological condition in children and is infrequently associated with primary Varicella (chickenpox) infection. We report the case of a 10‐year‐old previously healthy girl who developed simultaneous bilateral lower motor neuron facial weakness 3 weeks after a self‐limiting varicella infection.
Mohamed Sheikh Hassan +7 more
wiley +1 more source
Human herpesvirus type 6 in patients with systemic lupus erythematosus
Background and Objectives: Infectious agents are considered one of the possible etiological factors of systemic lupus erythematosus (SLE). It has been suggested that human herpesvirus type 6 (HHV-6) may trigger autoimmune disorders, but few studies have
Mohammad Shayestehpour +6 more
doaj +1 more source
ABSTRACT Consider human herpesvirus 6 (HHV‐6) in immunocompetent adults with viral meningitis when standard tests are negative. Qualitative CSF PCR requires cautious interpretation because it cannot exclude chromosomally integrated HHV‐6. Serial CSF improvement and rapid clinical recovery may support probable self‐limited infection and help avoid ...
Hatem M. Taha +5 more
wiley +1 more source
ABSTRACT Idiopathic multicentric Castleman disease can rarely present with systemic inflammation and erosive seronegative polyarthritis. Awareness of this association helps prevent misdiagnosis and ensures appropriate immunosuppressive management based on clinicopathological and immunohistochemical correlation.
Birahim Lo +9 more
wiley +1 more source
Pityriasis rosea during COVID-19 and its pathogenesis
Francesco Drago, MD +1 more
doaj +1 more source
Diagnostic pitfall in fever with CNS involvement: MOGAD. Fever accompanied by neurological symptoms was initially suspected as central nervous system infection. However, negative pathogen tests and failed anti‐infective therapy, followed by positive MOG‐IgG, led to a revised diagnosis of MOGAD. The patient responded favorably to corticosteroids or IVIG.
Ai Guo, Fu‐Dong Shi, Kaibin Shi
wiley +1 more source

