Recent human herpesvirus 6 (HHV-6) infection was detected in cases of exanthem subitum (ES) involving four children, aged 10 to 24 months, between April and August 1994, in Belém, Brazil.
R. B. de Freitas +4 more
doaj +1 more source
Killing of Kaposi's sarcoma-associated herpesvirus-infected fibroblasts during latent infection by activated natural killer cells. [PDF]
Kaposi's sarcoma-associated herpesvirus (KSHV) establishes life-long infection by evading clearance by the host immune system. In de novo infection and lytic replication, KSHV escapes cytotoxic T cells and NK cells through downregulation of MHC class-I ...
Nick C. Matthews +14 more
core +1 more source
Human herpesvirus-6A (HHV-6A) is rarer than HHV-6B in many infant populations. However, they are similarly prevalent as germline, chromosomally integrated genomes (ciHHV-6A/B).
Spyrou, MA +5 more
core +1 more source
Epidemiology and fitness effects of wood mouse herpesvirus in a natural host population [PDF]
Rodent gammaherpesviruses have become important models for understanding human herpesvirus diseases. In particular, interactions between murid herpesvirus 4 and Mus musculus (a non-natural host species) have been extensively studied under controlled ...
Pedersen, Amy B. +2 more
core +1 more source
Atypical manifestation of human herpes virus-6 encephalitis with extra-limbic lesions: a case report [PDF]
Human herpesvirus-6 (HHV-6) encephalitis represents a serious opportunistic infection in immunocompromised patients that is associated with substantial mortality and long-term neurological sequelae. The disease most often involves the limbic system, with
Soo Hyun Ahn, Seon-Jae Ahn, Kon Chu
doaj +1 more source
β-Herpesviruses in Febrile Children with Cancer
We conducted a cross-sectional study of β-herpesviruses in febrile pediatric oncology patients (n = 30), with a reference group of febrile pediatric solid-organ transplant recipients (n = 9).
Stephanie Yee-Guardino +10 more
doaj +1 more source
The ubiquitin system in normal and infected germinal center B cells
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis +2 more
wiley +1 more source
Gene expression studies of lytic infection and chromosomal integration of human herpesvirus 6. [PDF]
Human herpesvirus 6 (HHV-6) was discovered in 1986 in patients with lymphoproliferative diseases and it has a predominant tropism for CD4+ T cells in vitro and in vivo.
Tsao, E.H.F.
core
リンパ増殖性疾患とHuman herpesvirus 6 (HHV-6)の関連性のPCR法による検討(第1報)
Human herpesvirus 6 (HHV-6)は1986年に新たに発見されたウイルスであり様々な疾患との関連性が示唆されている。HHV-6とリンパ増殖性疾患との関連性を検討するために、このウイルスDNAに特異的なプライマーを作製し、それを用いたPCR法で、患者より採取した末梢血およびリンパ組織中のHHV-6ゲノムの検出を行った。 8名の健常人、40例のリンパ増殖性疾患、1例の慢性骨髄性白血病について検討したが、今回施行した49検体では、HHV-6は検出されず、HHV ...
サダ, エイジ +15 more
core +1 more source
The RING-CH ligase K5 antagonizes restriction of KSHV and HIV-1 particle release by mediating ubiquitin-dependent endosomal degradation of tetherin [PDF]
Tetherin (CD317/BST2) is an interferon-induced membrane protein that inhibits the release of diverse enveloped viral particles. Several mammalian viruses have evolved countermeasures that inactivate tetherin, with the prototype being the HIV-1 Vpu ...
Wilson, Sam J. +48 more
core +1 more source

