Results 41 to 50 of about 630,159 (243)

Human Herpesvirus 6 and Neuroinflammation [PDF]

ISRN Virology, 2013
Human herpesvirus (HHV-) 6A and HHV-6B are two distinctβ-herpesviruses which have been associated with various neurological diseases, including encephalitis, meningitis, epilepsy, and multiple sclerosis. Although the reactivation of both viruses is recognized as the cause of some neurological complications in conditions of immunosuppression, their ...
Reynaud, Joséphine M., Horvat, Branka
openaire   +2 more sources

Rainbow Kaposi's Sarcoma-Associated Herpesvirus Revealed Heterogenic Replication with Dynamic Gene Expression. [PDF]

, 2020
Molecular mechanisms of Kaposi's sarcoma-associated herpesvirus (KSHV) reactivation have been studied primarily by measuring the total or average activity of an infected cell population, which often consists of a mixture of both nonresponding and ...
Campbell, Mel, Chuang, Frank, Guevara-Plunkett, Sara, Izumiya, Chie, Izumiya, Yoshihiro, Kumar, Ashish, Luxardi, Guillaume, Lyu, Yuanzhi, Nakajima, Ken-Ichi, Soulika, Athena, Wang, Kang-Hsin   +10 more
core  

Movement Disorders in Aicardi–Goutières Syndrome and Response to Immunomodulation

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT This study characterizes movement disorders and treatment responses in seven children with Aicardi–Goutières syndrome (AGS). We retrospectively evaluated motor phenotypes, neuroimaging, and interferon signatures in patients treated with baricitinib or anifrolumab. Spasticity affected all patients, while dystonia was present in 4/7.
Enrique Gonzalez Saez‐Diez, Monica Ferrer Socorro, Kathryn Yang, Nicole Battaglia, Zainab Zaman, Mariko Bennett, Adeline Vanderver, Pui Y. Lee, Lauren A. Henderson, Milena M. Andzelm, Darius Ebrahimi‐Fakhari   +10 more
wiley   +1 more source

HHVs AND LYMPHOPROLIFERATIVE DISORDERS

Mediterranean Journal of Hematology and Infectious Diseases, 2011
Epstein-Barr virus (EBV) is a γ herpesvirus well recognized to be involved in the development of human B (Hodgkin and non Hodgkin lymphomas) and NK/T cell lymphomas, either in the general population or in the immunosuppressed individuals.
C Quadrelli, P Barozzi, G Riva, Mario Luppi   +3 more
doaj   +1 more source

Endogenization and excision of human herpesvirus 6 in human genomes.

PLoS Genetics, 2020
Sequences homologous to human herpesvirus 6 (HHV-6) are integrated within the nuclear genome of about 1% of humans, but it is not clear how this came about. It is also uncertain whether integrated HHV-6 can reactivate into an infectious virus.
Xiaoxi Liu, Shunichi Kosugi, Rie Koide, Yoshiki Kawamura, Jumpei Ito, Hiroki Miura, Nana Matoba, Motomichi Matsuzaki, Masashi Fujita, Anselmo Jiro Kamada, Hidewaki Nakagawa, Gen Tamiya, Koichi Matsuda, Yoshinori Murakami, Michiaki Kubo, Amr Aswad, Kei Sato, Yukihide Momozawa, Jun Ohashi, Chikashi Terao, Tetsushi Yoshikawa, Nicholas F Parrish, Yoichiro Kamatani   +22 more
doaj   +1 more source

HHV-6 Infection in a 19-Year-Old Liver Transplant Recipient – Much More Than Roseola!

IDCases, 2023
Human herpesvirus 6 (HHV-6) infections, most commonly occurring during childhood, are frequently mild and self-limited. However, immunosuppression due to transplantation may cause reactivation of HHV-6 with manifestations ranging from fever and skin ...
Alleyna Dougherty, Nathan DeRon, Jr., Leigh Hunter   +2 more
doaj   +1 more source

Human herpesvirus-6 infection in liver transplantation [PDF]

, 2007
Rejection and infections are the two most common complications after liver transplantation. Human herpesvirus-6 (HHV-6) belongs to the betaherpesviruses, together with its close relatives cytomegalovirus (CMV) and human herpesvirus-7 (HHV-7).
Härmä, Maiju
core  

Statistical properties of thermodynamically predicted RNA secondary structures in viral genomes

, 2008
By performing a comprehensive study on 1832 segments of 1212 complete genomes of viruses, we show that in viral genomes the hairpin structures of thermodynamically predicted RNA secondary structures are more abundant than expected under a simple random ...
A. Tuplin, C. Thurner, D.S.H. Chew, F. Lillo, F. Lillo, F. Lillo, F. Ratcliff, G.P. Schroth, H.O. Smith, J.S. Mattick, M. Spanò, M. Spanò, M.Y. Leung, P. Rice, P. Simmonds, P.E. Warburton, R. Cox, R. N. Mantegna, R.C. Lee, S. Miccichè, S.R. Eddy   +20 more
core   +1 more source

Esclerose múltipla e interação com os herpesvirus [PDF]

, 2013
Multiple sclerosis is the most common autoimmune inflammatory demyelinating disease of the central nervous system, and its etiology is believed to have both genetic and environmental components.
Cavenaghi, Vitor Breseghello, Fink, Maria Cristina Domingues da Silva, Lima, Bruna Mendonça, Nali, Luis Henrique, Olival, Guilherme Sciascia do, Oliveira, Augusto César Penalva de, Romano, Camila Malta, Serafim, Vitor, Sumita, Laura Masami, Thomaz, Rodrigo Barbosa, Tilbery, Charles Peter   +10 more
core   +2 more sources

RNF213 Is an Interferon‐Stimulated Gene That Targets Influenza A Virus NP and Activates MDA5 to Restrict Infection

Advanced Science, EarlyView.
RNF213 is characterized as a dual‐functional antiviral effector. It directly mediates the degradation of the influenza A virus nucleoprotein (NP) while simultaneously activating the MDA5‐mediated innate immune signaling pathway. This coordinated response establishes a powerful host defense system against viral infection. ABSTRACT Influenza A virus (IAV)
Haoning Li, Yuying Zhang, Jingjing Wang, Qianqian Zhang, Hailiang Sun, Fanhua Wei   +5 more
wiley   +1 more source