Results 151 to 160 of about 8,383,878 (290)

Efficacy of High‐Dose Intravenous Anakinra in Pediatric TAFRO Syndrome: Report of Two Cases and Literature Review

open access: yesPediatric Blood &Cancer, Volume 72, Issue 8, August 2025.
ABSTRACT TAFRO (thrombocytopenia, anasarca, fever, reticulin fibrosis, renal insufficiency, and organomegaly) syndrome is a rare, life‐threatening inflammatory condition linked to infections, neoplasms, and idiopathic multicentric Castleman disease. Interleukin (IL)‐6 inhibitors are the primary treatment, but refractory cases require alternatives. This
Serena Palmeri   +10 more
wiley   +1 more source

Protease mimicry: Dissecting the ester bond crosslinking mechanics in bacterial adhesin proteins

open access: yesProtein Science, Volume 34, Issue 8, August 2025.
Abstract The ester bond crosslink discovered within bacterial adhesin proteins offers a captivating insight into the convergent evolution of enzyme‐like machinery. Crystal structures reveal a putative catalytic triad comprising an acid–base–nucleophile combination and an oxyanion‐like site that suggests a serine protease‐like mechanism drives the ...
Yuliana Yosaatmadja   +13 more
wiley   +1 more source

Human Herpesvirus 6: An Emerging Pathogen [PDF]

open access: diamond, 1999
Gabriella Campadelli‐Fiume   +2 more
openalex   +1 more source

Torque teno virus as a marker of immune status in immunocompromised patients: A systematic review

open access: yesEuropean Journal of Clinical Investigation, Volume 55, Issue 8, August 2025.
Abstract Background Torque teno virus (TTV) is not known to cause disease in humans; however, chronic inflammatory conditions and immunosuppression states can favour TTV replication. This study aimed to verify the effectiveness of TTV as an immune biomarker.
Janaina B. Medina   +8 more
wiley   +1 more source

Molecular Mechanisms Underlying Response to Influenza in Grey Seals (Halichoerus grypus), a Potential Wild Reservoir

open access: yesMolecular Ecology, Volume 34, Issue 15, August 2025.
ABSTRACT RNA viruses are infamous for their ability to cross species barriers, posing threats to global health and security. Influenza A virus (IAV) is naturally found in avian hosts but periodically spills over into marine wildlife. IAV outbreaks occur in the Northwest Atlantic, but grey seals (Halichoerus grypus) appear to be less susceptible to IAV ...
Christina M. McCosker   +7 more
wiley   +1 more source

Human sporadic breast carcinoma histotypes driven by the Human Betaretrovirus homologous to Mouse Mammary Tumor Virus

open access: yesInternational Journal of Cancer, Volume 157, Issue 2, Page 371-383, 15 July 2025.
What's new? While estrogens, obesity, and alcohol are recognized risk factors for breast cancer, a viral hypothesis has been suggested based on the murine model of Mouse Mammary Tumor Virus (MMTV)‐induced mammary tumors. This study analyzed sequences of the human homolog of MMTV across human breast carcinoma histotypes, detecting the virus in all types
Prospero Civita   +12 more
wiley   +1 more source

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