Reproxalap ‐ A Novel Treatment Option for Allergic Conjunctivitis – A Comprehensive Narrative Review
ABSTRACT Background and Aims Allergic conjunctivitis is a prevalent, immune‐mediated hypersensitivity disorder of the ocular surface affecting 10%–20% of the global population. Current therapeutic options, while effective to some extent, are often limited by side effects and inconsistent efficacy.
Sanila Mughal +7 more
wiley +1 more source
Primary Cancer Prevention Through Vaccination: Advances, Challenges, and Global Perspectives
ABSTRACT Oncogenic viral and bacterial infections constitute a significant portion of the global cancer burden, accounting for up to 15% of cases, particularly in low‐ and middle‐income countries. Prophylactic vaccination thus appears to be the most effective tool for preventing these preventable cancers, especially those linked to human papillomavirus
Christian Tague +5 more
wiley +1 more source
ABSTRACT Background This study aimed to investigate the epidemiological trends, age‐ and sex‐related patterns, and clinical and immunological characteristics of Epstein–Barr virus (EBV) infection among febrile children. Methods We analyzed EBV DNA data from 9151 febrile children and serological antibody profiles from 6934 cases.
Hao Zhou +4 more
wiley +1 more source
ABSTRACT Naked viruses of the family Picornaviridae commonly spread via lysis of infected cells. Recent studies indicate that, prior to cell lysis, naked viruses are packaged and released inside extracellular vesicles (EVs). This has been considered a pro‐viral mechanism because EV membranes protect enclosed virions from neutralizing antibodies.
Xinyi Pei +9 more
wiley +1 more source
Prevalence of HSV-1, HSV-2, EBV, and HHV-8 Co-Infections Among HPV-Positive Women: A Cross-Sectional Study from Iran. [PDF]
Safarnezhad Tameshkel F +8 more
europepmc +1 more source
Upper Airway Obstruction due to Kaposi Sarcoma—Presenting Sign of HIV: Case Report and Review
This study presents a case of undiagnosed HIV presenting with Kaposi sarcoma (KS) of the head and neck with acute upper airway obstruction (UAO) and provides an updated scoping literature review to examine the patient characteristics, lesion characteristics, interventions, and outcomes of KS cases with UAO from the pharynx, larynx, and/or trachea.
Zachary A. Wykoff +3 more
wiley +1 more source
Concurrent HHV-8-Associated Multicentric Castleman Disease and Kaposi Sarcoma in an HIV-Negative Patient: A Case Report. [PDF]
Vasile AM +4 more
europepmc +1 more source
Kaposiform hemangioendothelioma: Diagnosis and treatment
Vascular endothelial growth factor‐C (VEGF‐C)/vascular endothelial growth factor receptor‐3 (VEGFR‐3) and angiopoietin‐2 (Ang‐2)/tyrosine kinase with immunoglobulin‐like and EGF‐like domain 2 (TIE2) signaling pathways play an important role in lymphangiogenesis.
Yi Tian +5 more
wiley +1 more source
Clinical characteristics and prognostic analysis of patients with herpesvirus meningitis/encephalitis based on cerebrospinal fluid mNGS positivity. [PDF]
Yang H, Zhao L.
europepmc +1 more source
Molecular Mimicry Between Epstein-Barr Virus and Human Herpesvirus-6 Proteins and Central Nervous System Proteins: Implications for T and B Cell Immunogenicity in an In Silico Study. [PDF]
Almulla AF +3 more
europepmc +1 more source

