Results 11 to 20 of about 172,650 (280)
Human Herpesvirus 8 infection may contribute to oxidative stress in diabetes type 2 patients [PDF]
BMC Research Notes, 2020 Objective To investigate the link between Human Herpesvirus 8 (HHV8) infection and plasma oxidative stress in patients with diabetes mellitus type 2 (DM2).
Alessandra Incani +6 more
doaj +4 more sources
Human herpesvirus type 1 and type 2 disrupt mitochondrial dynamics in human keratinocytes [PDF]
Archives of Virology, 2018 Mitochondrial movement and distribution throughout the cytoplasm is crucial for maintaining cell homeostasis. Mitochondria are dynamic organelles but can be functionally disrupted during infection. Here, we show that the ubiquitous human pathogens HHV-1 and HHV-2 induce changes in the mitochondrial morphology and distribution in the early and late ...
Marcin Chodkowski +9 more
openalex +4 more sources
Virology, 2003 In the present work we report the cloning of a full-length cDNA encoding the immediate-early (IE) 2 protein from human herpesvirus 6 (HHV-6) variant A (GS strain). The transcript is 4690 nucleotides long and composed of 5 exons. Translation initiation occurs within the third exon and proceeds to the end of U86.
Annie Gravel +4 more
openalex +4 more sources
Ex vivo protocol for testing virus survival on human skin: experiments with herpesvirus 2 [PDF]
Applied and Environmental Microbiology, 1996 We report an ex vivo method, which uses pieces of human skin excised during routine plastic surgery, for testing survival of hazardous pathogens. Using this procedure, we compared the survival of human herpesvirus 2 on human skin and on metal disks. At the physiological skin temperature of 32 degrees C, the half-life of the virus on skin was 1.44 h ...
Michael Graham +2 more
openalex +4 more sources
Human Herpesvirus 6 Immediate‐Early 2 Protein Interacts with Heterogeneous Ribonucleoprotein K and Casein Kinase 2 [PDF]
Microbiology and Immunology, 2004 AbstractHuman herpesvirus 6 (HHV‐6) immediate‐early (IE) 2 protein (IE2) may play important but incompletely defined roles during infection. We used yeast two‐hybrid screening to detect proteins interacting with HHV‐6 IE2, and found heterogeneous nuclear ribonucleoprotein K (hnRNP K) and the beta subunit of casein kinase 2 (CK2β) specifically ...
Kazuya Shimada +2 more
openalex +4 more sources
Inhibition of Interleukin-2 Gene Expression by Human Herpesvirus 6B U54 Tegument Protein [PDF]
Journal of Virology, 2014 ABSTRACTHuman herpesvirus 6B (HHV-6B) is a ubiquitous pathogen causing lifelong infections in approximately 95% of humans worldwide. To persist within its host, HHV-6B has developed several immune evasion mechanisms, such as latency, during which minimal proteins are expressed, and the ability to disturb innate and adaptive immune responses.
Mathieu Iampietro +3 more
openalex +4 more sources
Mapping of human herpesvirus 6 immediate–early 2 protein transactivation domains
Virology, 2006 The immediate-early 2 (IE2) protein of human herpesvirus 6 (HHV-6) is a potent transactivator of multiple cellular and viral promoters. Deletion mutants of HHV-6 variant A IE2 allowed us to map functional transactivation domains acting on complex and minimal promoter sequences.
Andru Tomoiu +2 more
openalex +4 more sources
Nectin-2 Acts as a Viral Entry Mediated Molecule That Binds to Human Herpesvirus 6B Glycoprotein B [PDF]
Viruses, 2022 Human herpesvirus 6B (HHV-6B) is a T-lymphotropic virus and the etiological agent of exanthem subitum. HHV-6B is present in a latent or persistent form after primary infection and is produced in the salivary glands or transmitted to this organ. Infected individuals continue to secrete the virus in their saliva, which is thus considered a source for ...
Hirohito Ogawa +5 more
openalex +6 more sources
Measurement of Antibodies to Herpesvirus Types 1 and 2 in Human Sera [PDF]
The Journal of Immunology, 1970 Abstract When varying dilutions of human sera were mixed with constant amounts of the two types of herpesvirus, it was observed that either type 1 virus was neutralized at a greater serum dilution than type 2, type 2 was neutralized at a greater serum dilution than type 1, or the two types were neutralized equally well.
William E. Rawls +3 more
openalex +3 more sources