Results 71 to 80 of about 600,594 (244)

Herpesvirus Simplex Virus‐1 Exploits Inflammation to Infect Periodontal Stem Cells and Disrupt Lineage Commitment

open access: yesJournal of Periodontal Research, EarlyView.
HSV‐1 infects oral mesenchymal stem cells both in vitro and in vivo to dysregulate their lineage commitment. An inflamed gingival environment increases susceptibility to HSV‐1 infection, which further elevates proinflammatory cytokine levels and exacerbates alveolar bone loss.
Araceli Valverde   +9 more
wiley   +1 more source

The Role of Viruses in the Pathogenesis of Periodontitis

open access: yesJournal of Periodontal Research, EarlyView.
This narrative review aimed to summarize current evidence on the presence and potential pathogenic role of viruses in periodontitis. Design: Narrative Review; Population: Patients with periodontitis; Exposure: Detection of viruses in oral samples (biopsies, saliva, gingival crevicular fluid, subgingival plaque, blood); Outcome: Viral prevalence, load ...
Kim Natalie Stolte   +2 more
wiley   +1 more source

Immune involvement in neuropsychiatric disorders: Insights from single‐cell transcriptomic studies

open access: yesPsychiatry and Clinical Neurosciences, EarlyView.
Neuropsychiatric disorders pose profound challenges to both research and treatment, largely due to their clinical heterogeneity and the limited understanding of their underlying biological mechanisms. While bulk RNA sequencing (bulk RNA‐seq) has been widely used to study gene expression, it cannot resolve cell‐type‐specific signals or detect rare ...
Tsutomu Takeda   +4 more
wiley   +1 more source

Blood-borne and sexually transmitted infections: a cross-sectional study in a Swiss prison

open access: yesBMC Infectious Diseases, 2018
Background Incarcerated people carry a high burden of infection, including blood-borne diseases (BBDs). It is also known that one million people contract a sexually transmitted infection (STI) every day worldwide, which represents a global public health ...
Komal Chacowry Pala   +5 more
doaj   +1 more source

Herpesvirus pan encodes a functional homologue of BHRF1, the Epstein-Barr virus v-Bcl-2

open access: yesBMC Microbiology, 2005
Background Epstein-Barr virus (EBV) latently infects about 90% of the human population and is associated with benign and malignant diseases of lymphoid and epithelial origin.
Williams Tracey   +2 more
doaj   +1 more source

Kaposi's sarcoma associated herpesvirus G protein-coupled receptor immortalizes human endothelial cells by activation of the VEGF receptor-2/ KDR [PDF]

open access: bronze, 2003
Carlos Bais   +8 more
openalex   +1 more source

Stewardship of Molecular Diagnostics in Transplant Viral Infections

open access: yesTransplant Infectious Disease, EarlyView.
ABSTRACT The transplant environment requires special considerations when testing for viral infections as immunosuppression results in atypical infection profiles. Microbes otherwise considered commensals or causing mild disease can lead to severe infections in transplant environments. Therefore, guidelines tend to recommend broader microbial testing in
Scott Sugden   +3 more
wiley   +1 more source

Acyclovir‐Resistant Herpes Simplex Virus in Pediatric Patients Undergoing Allogeneic Hematopoietic Stem Cell Transplant: A Case Series

open access: yesTransplant Infectious Disease, EarlyView.
This retrospective case series of acyclovir‐resistant HSV infection in pediatric patients undergoing allogeneic HSCT discusses the clinical course, associated complications, and treatment, including side effects. We propose the first algorithm for investigating and managing acyclovir‐resistant HSV infections in pediatric HSCT recipients, highlighting ...
Jenna Nunn   +9 more
wiley   +1 more source

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