Results 91 to 100 of about 601,020 (224)

Sharing Is Caring?—Pathogens and Pathogen‐Specific Antibodies in Arctic Endemic Seal Species and the Newly Sympatric Harbor Seals in Kongsfjorden, Svalbard

Marine Mammal Science, Volume 42, Issue 2, April 2026.
ABSTRACT Climate change associated transformations of Arctic marine ecosystems are having detrimental impacts on Arctic endemic marine mammals. However, warming conditions are providing new habitats for temperate marine mammals, some of which are expanding into Arctic regions, posing a threat of novel pathogen introduction and disease transmission.
Luca A. Schick, Kit M. Kovacs, Christian Lydersen, Simon Rohner, Ellen Prenger‐Berninghoff, Carsten Heydel, Christa Ewers, Alexander Postel, Nele Gremmel, Paul Becher, Christina Strube, Ursula Siebert   +11 more
wiley   +1 more source

EGR Proteins Mediate Interferon‐Independent Anti‐HSV‐1 Responses Through Viral and Host Targets

Advanced Science, Volume 13, Issue 13, 3 March 2026.
Early antiviral responses are typically mediated by interferons. However, during HSV‐1 infection, host early growth response (Egr) genes, which are not interferon‐stimulated genes, are quickly induced by viral protein ICP0. EGR proteins, in turn, suppress viral lytic infection by activating viral latency‐associated (LAT) and host immune regulatory ...
Shuaishuai Wang, Fujun Hou, Xunuo Jin, Yuhang Xiang, Dongli Pan   +4 more
wiley   +1 more source

Features of the course of viral hepatitis A in a child with persistent mixed herpesvirus infection

Лечащий Врач
Background. Today in the structure of viral hepatitis viral hepatitis A takes the lead position, the course of typical forms is usually favorable. Over the last few years, however, the frequency of viral hepatitis A has become higher, with increased ...
E. G. Khramtsova, M. D. Subbotina
doaj   +1 more source

Herpesvirus genome integration in whole‐genome sequences of dementia and control cohorts

Alzheimer's &Dementia, Volume 22, Issue 3, March 2026.
Abstract INTRODUCTION The infectious hypothesis suggests that microbes like herpesviruses may play a role in the pathogenesis of Alzheimer's disease (AD) and other related dementias through methods that may include viral genome integration. The occurrence of herpesvirus genome integration in dementia patients has not been thoroughly characterized ...
Stacey L. Piotrowski, Mary Alice Allnutt, Kory Johnson, Toshiko Tanaka, Luigi Ferrucci, Huw Morris, John Hardy, PROSPECT Consortium, Mina Ryten, United Kingdom Brain Expression Consortium (UKBEC), Giancarlo Logroscino, Juan Troncoso, Thomas G. Beach, Geidy E. Serrano, Carlos Cruchaga, Dennis W. Dickson, Owen A. Ross, Adriano Chiò, International LBD Genomics Consortium, International ALS Genomics Consortium, Henry Houlden, The American Genome Center, Clifton L. Dalgard, Jinhui Ding, J. Raphael Gibbs, Bryan J. Traynor, Sonja W. Scholz, Steven Jacobson   +27 more
wiley   +1 more source

A Rare Case of Pediatric Gastric Inflammatory Myofibroblastic Tumor (IMT) Mimicking Gastrointestinal Stromal Tumor (GIST): A Case Report

Clinical Case Reports, Volume 14, Issue 3, March 2026.
ABSTRACT Gastric inflammatory myofibroblastic tumor is a rare entity in children that may present with nonspecific gastrointestinal symptoms. Complete surgical excision remains both diagnostic and curative, with favorable postoperative outcomes and low recurrence risk when adequately resected.
Rajabu Athumani Bakari, Alfred Chibwae, Amour Ally Mwinyi, Alex Mashaka, Catherine Mtui, Aidah Kenseko, Boniface Kahindi Kazungu, William Malinda Lutege, Godfrey Masalu Mchele   +8 more
wiley   +1 more source

Manufacturing and clinical applications of non‐CAR‐T immune effector cells

Transfusion, EarlyView.
Thane Kubik, Theodros Mamo, David H. McKenna   +2 more
wiley   +1 more source

Safeguarding a Flagship Species: Integrated Surveillance of Cross‐Species Pathogen Transmission in Giant Panda Ecosystems

Ecology and Evolution, Volume 16, Issue 3, March 2026.
Emerging infectious diseases increasingly threaten giant pandas and cohabiting species. This review analyzes pathogen transmission risks from domestic animals, wildlife, and vectors and proposes an integrated genomic surveillance framework for early warning and biodiversity conservation.
Xiaoli Sun, Yi Peng, Xiaoye Hao, Rong Dong, Zhilin Wang, Le Wang, Chengdong Wang, Xiangdong Wu, Zheng Chen, Wenbo Zhang, Xiaoli Tang   +10 more
wiley   +1 more source

Viral Immunity in Immunoglobulin Products: Global Immunity Debt and Autoimmunity in the Postpandemic Era

European Journal of Immunology, Volume 56, Issue 3, March 2026.
Immunoglobulin products derived from pooled global plasma reflect population‐level antiviral immunity. Analysis of batches from 2017 to 2023 reveals pandemic‐driven shifts in viral antibody profiles and a concurrent rise in autoantibodies, notably against TRIM21/Ro52, highlighting links between SARS‐CoV‐2, immunity debt, and autoimmunity.
Hannes Lindahl, Katy Shaw‐Saliba, H. Benjamin Larman, C. I. Edvard Smith, Peter Bergman   +4 more
wiley   +1 more source

A clinicopathologic analysis of primary central nervous system lymphomatoid granulomatosis: case report and literature review

Chinese Journal of Contemporary Neurology and Neurosurgery, 2012
Objective To investigate the clinical, neuroimaging and histopathological features of primary central nervous system lymphomatoid granulomatosis (LG).
Yong⁃juan FU, Yue⁃shan PIAO, Li CHEN, Cun⁃jiang LI, De⁃hong LU   +4 more
doaj  

CD4‐Based Chimeric Antigen Receptor (CAR)‐T Cells With Resistance to HIV‐1 Infection and Enhanced Anti‐HIV Efficacy: Covalent Interaction Between CD4‐CAR and HIV‐1 Envelope Glycoprotein

Journal of Medical Virology, Volume 98, Issue 3, March 2026.
ABSTRACT The current highly active antiretroviral therapy (HAART or ART) effectively suppresses de novo HIV‐1 infection but fails to eliminate HIV reservoir cells, which leads to rapid viral rebound upon ART cessation. Chimeric antigen receptor (CAR) T cells engineered to target HIV‐1 Env⁺ cells offer a promising strategy to eliminate or control these ...
Yaoxian Lou, Xiuting He, Guangming Li, Martin Sikhondze, Jianping Ma, Hongwei Du, Xin Ouyang, Gianpietro Dotti, Mohammad Sajadi, Lishan Su   +9 more
wiley   +1 more source