Epstein‒Barr virus and human herpesvirus 6 infection in patients with systemic lupus erythematosus. [PDF]
Chen X, Li H, Wu C, Zhang Y.
europepmc +1 more source
KSHV vIL6 Inhibits Functional B Cell Maturation During De Novo Infection
ABSTRACT Despite causative links to lymphoproliferative disorders, little is known about early events governing KSHV infection in B lymphocytes. IL‐6 signaling plays a critical role in KSHV‐mediated disease, with human IL‐6 (hIL6) levels correlating with viral load and disease progression.
Wajd Zakir+2 more
wiley +1 more source
Chromosome-Specific Human Herpesvirus 6 Integration and Hematologic Malignancies. [PDF]
Heldman MR+12 more
europepmc +1 more source
Endoplasmic Reticulum Stress in Cancer
Persistent ER stress in tumors activates UPR sensors (IRE1α, PERK, ATF6), driving cancer proliferation, metastasis, immune evasion, and drug resistance. This review explores UPR‐mediated signaling crosstalk, angiogenesis, and therapeutic targeting to develop safer anticancer strategies.
Ruixin Zhou+5 more
wiley +1 more source
Associations between Oral Human Herpesvirus-6 and -7 and Periodontal Conditions in Older Adults. [PDF]
Hamada N+11 more
europepmc +1 more source
Abstract Infectious diseases impact numerous organisms. Knowledge of host‐pathogen interactions and host responses to infection is crucial for conservation and management. Obtaining this knowledge quickly is made increasingly possible by a variety of genomic approaches, yet, for many species the bottleneck to understanding this, remains access to ...
Allison K. Miller+7 more
wiley +1 more source
Immunopathogenic Insights on Preferential Human Herpesvirus-6 Reactivation in Drug Rash With Eosinophilia and Systemic Symptoms: A Scoping Review. [PDF]
Zhu H, Ren V.
europepmc +1 more source
Trafficking to the Plasma Membrane of the Seven-Transmembrane Protein Encoded by Human Herpesvirus 6 U51 Gene Involves a Cell-Specific Function Present in T Lymphocytes [PDF]
Laura Menotti+3 more
openalex +1 more source
SQSTM1/p62 Orchestrates Skin Aging via USP7 Degradation
p62 exhibits diminished expression in aging skin and senescent cells. p62 serves to inhibit the accumulation of USP7 during senescence induction. The Tyr‐67 residue within the PB1 domain or Gln‐418 within the UBA domain of p62 forms a hydrogen bond with Ala‐993 of the Ubl5 domain of USP7.
Liu Chen+10 more
wiley +1 more source