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Human Herpesvirus 6 [PDF]

Clinical Infectious Diseases, 2001
The development of techniques for the culture of lymphoid cells and the isolation of viruses that infect these cells led to the discovery of human herpesvirus (HHV) 6 in 1986. At the time, HHV-6 was the first new human herpesvirus to be discovered in roughly a quarter of a century, and its isolation marked the beginning of an era of discovery in ...
M T, Caserta, D J, Mock, S, Dewhurst
openaire   +3 more sources

Human Herpesvirus 6 and Malignancy: A Review

Frontiers in Oncology, 2018
In order to determine the role of human herpesvirus 6 (HHV-6) in human disease, several confounding factors, including methods of detection, types of controls, and the ubiquitous nature of the virus, must be considered.
Eva Eliassen, Emily Lum, Joshua Pritchett, Joseph Ongradi, Gerhard Krueger, John R. Crawford, Tuan L. Phan, Tuan L. Phan, Dharam Ablashi, Stanley David Hudnall   +9 more
doaj   +2 more sources

Endogenization and excision of human herpesvirus 6 in human genomes.

PLoS Genetics, 2020
Sequences homologous to human herpesvirus 6 (HHV-6) are integrated within the nuclear genome of about 1% of humans, but it is not clear how this came about. It is also uncertain whether integrated HHV-6 can reactivate into an infectious virus.
Xiaoxi Liu, Shunichi Kosugi, Rie Koide, Yoshiki Kawamura, Jumpei Ito, Hiroki Miura, Nana Matoba, Motomichi Matsuzaki, Masashi Fujita, Anselmo Jiro Kamada, Hidewaki Nakagawa, Gen Tamiya, Koichi Matsuda, Yoshinori Murakami, Michiaki Kubo, Amr Aswad, Kei Sato, Yukihide Momozawa, Jun Ohashi, Chikashi Terao, Tetsushi Yoshikawa, Nicholas F Parrish, Yoichiro Kamatani   +22 more
doaj   +2 more sources

Prevalence of Chromosomally Integrated Human Herpesvirus 6 in Patients with Human Herpesvirus 6–Central Nervous System Dysfunction [PDF]

Biology of Blood and Marrow Transplantation, 2014
We identified 37 hematopoietic cell transplantation recipients with human herpesvirus 6 (HHV-6) central nervous system dysfunction and tested donor-recipient pairs for chromosomally integrated HHV-6 (ciHHV-6).
Beranzoli, Laura, Dañobeitia, Juan José, Del Rio, Joaquin, Garcia, Oscar, Jesus, Sergio M, Kassis, Dimitris, Lanteri, Nadine, Legrand, Julien, Marinaro, Giuditta, Martinez Padro, Enoc, Moreau, Bertrand, Nogueras Cervera, Marc, Rolin, Jean-Francois, Toma, Daniel Mihai   +13 more
core   +2 more sources

Latency, Integration, and Reactivation of Human Herpesvirus-6

Viruses, 2017
Human herpesvirus-6A (HHV-6A) and human herpesvirus-6B (HHV-6B) are two closely related viruses that infect T-cells. Both HHV-6A and HHV-6B possess telomere-like repeats at the terminal regions of their genomes that facilitate latency by integration into
Shara N. Pantry, Peter G. Medveczky
doaj   +2 more sources

Comparative genomic, transcriptomic, and proteomic reannotation of human herpesvirus 6

BMC Genomics, 2018
Background Human herpesvirus-6A and -6B (HHV-6) are betaherpesviruses that reach > 90% seroprevalence in the adult population. Unique among human herpesviruses, HHV-6 can integrate into the subtelomeric regions of human chromosomes; when this occurs in ...
Alexander L. Greninger, Giselle M. Knudsen, Pavitra Roychoudhury, Derek J. Hanson, Ruth Hall Sedlak, Hong Xie, Jon Guan, Thuy Nguyen, Vikas Peddu, Michael Boeckh, Meei-Li Huang, Linda Cook, Daniel P. Depledge, Danielle M. Zerr, David M. Koelle, Soren Gantt, Tetsushi Yoshikawa, Mary Caserta, Joshua A. Hill, Keith R. Jerome   +19 more
doaj   +2 more sources

Human herpesvirus-6 infection in a critically ill and immunocompetent patient: a case report [PDF]

Journal of Medical Case Reports
Background Human herpesvirus-6 is a rare infection in an immunocompetent adult. In existing literature, there is a dearth of knowledge that mainly exists as case reports and case series.
Xin Tian Chia, Hai Liang Marc Wong, Jia Shen Loh   +2 more
doaj   +2 more sources

Human herpesvirus 6 [PDF]

Orvosi Hetilap, 2010
Az 1986-ban felfedezett emberi 6-os herpeszvírus A és B változata molekuláris tulajdonságai alapján a legősibb emberi herpeszvírus. A B változat cseppfertőzéssel terjed a tünetmentes vírusürítő felnőttekről a két év alatti kisgyermekekre, akikben alkalmilag exanthema subitum jöhet létre.
Ongrádi, József, Kövesdi, Valéria, Medveczky, G. Péter   +2 more
  +7 more sources

Human herpesvirus 6 [PDF]

Clinical Microbiology Reviews, 1997
Human herpesvirus 6 variant A (HHV-6A) and human herpesvirus 6 variant B (HHV-6B) are two closely related yet distinct viruses. These visuses belong to the Roseolovirus genus of the betaherpesvirus subfamily; they are most closely related to human herpesvirus 7 and then to human cytomegalovirus.
D K, Braun, G, Dominguez, P E, Pellett
openaire   +4 more sources

Human Herpesvirus 6 Encephalitis in Immunocompetent and Immunocompromised Hosts

Neurology: Neuroimmunology & Neuroinflammation, 2021
Objective The aim of this study was to analyze the clinical, radiologic, and biological features associated with human herpesvirus 6 (HHV-6) encephalitis in immunocompetent and immunocompromised hosts to establish which clinical settings should prompt ...
G. Berzero, G. Campanini, E. Vegezzi, M. Paoletti, A. Pichiecchio, A. Simoncelli, A. Colombo, P. Bernasconi, O. Borsani, Angela Maria Di Matteo, V. Rossi, T. Foiadelli, S. Savasta, Francesca Compagno, M. Zecca, F. Baldanti, E. Marchioni   +16 more
semanticscholar   +1 more source