Pityriasis Rosea is Associated with Systemic Active Infection with Both Human Herpesvirus-7 and Human Herpesvirus-6 [PDF]
Pityriasis rosea is a common skin disease that has been suspected to have a viral etiology. We performed nested polymerase chain reaction to detect human herpesvirus-7, human herpesvirus-6, and cytomegalovirus DNA in lesional skin, nonlesional skin ...
Kawamura, Tatsuyoshi +6 more
core +1 more source
Seven‐year surveillance reveals a cold‐adapted OsHV‐1 lineage in blood clams, with disease onset at 13°C—3–5°C lower than in oysters—and identifies asymptomatic carriers and facility effluent as key transmission routes. ABSTRACT Ostreid herpesvirus 1 (OsHV‐1) poses a major threat to bivalve aquaculture, but its impact on blood clams (Anadara ...
Xiang Zhang +7 more
wiley +1 more source
Objectives CASTOR1 senses arginine and regulates mammalian target of rapamycin complex 1 (mTORC1), a central metabolic signaling molecule. This study aimed to elucidate the roles of CASTOR1 in humoral immune responses. Methods We analyzed human B cell transcriptomes from healthy controls and patients with systemic lupus erythematosus (SLE) via ...
Takeshi Kusuda +5 more
wiley +1 more source
What Makes an “Ideal” Cell Line for Recombinant Adeno‐Associated Virus Production?
Several host cell types have been used to produce rAAVs to date. Cell line‐specific traits that are beneficial in the context of rAAV manufacturing are reviewed here, with the goal of developing a consensus on the ‘ideal’ characteristics that an rAAV production host should possess (created with Biorender.com).
James Conheady +6 more
wiley +1 more source
Purification and concentration of model viruses using single‐pass tangential flow filtration
Single‐pass TFF was developed for an enveloped and non‐enveloped virus for use in continuous downstream purification processes. Enveloped virus was concentrated and purified. Abstract The vaccine and viral vector industry is growing at an accelerated rate.
Luis Alberto Mejía‐Manzano +6 more
wiley +1 more source
Sensitive detection systems for infectious agents in xenotransplantation*
Abstract Xenotransplantation of pig cells, tissues, or organs may be associated with transmission of porcine microorganisms, first of all of viruses, to the transplant recipient, potentially inducing a disease (zoonosis). I would like to define detection systems as the complex of sample generation, sample preparation, sample origin, time of sampling ...
Joachim Denner
wiley +1 more source
Diagnostic Usefulness of Cell Block Samples in Fluid Overload‐Associated Large B‐Cell Lymphoma
ABSTRACT Fluid overload‐associated B‐cell lymphoma (FO‐LBCL) is a B‐cell neoplasm that presents as serous effusions without detectable tumor masses and Kaposi sarcoma‐associated herpesvirus (KSHV)/human herpesvirus 8 (HHV8) infection. Here, we report a case of an 81‐year‐old female patient with FO‐LBCL (Stage IVA) who presented with pericardial and ...
Hiroyuki Okanishi +14 more
wiley +1 more source
Role of the human beta-herpesviruses in organ allograft rejection following transplantation. [PDF]
In previous prospective studies conducted in our department, PCR was used to detect the three ({dollar}-herpesviruses, human cytomegalovirus (HCMV), and human herpesviruses 6 and 7 (HHV-6 and HHV-7) in the blood of solid organ transplant patients.
Li, Y.T., Li, Yingting
core
Antibody kinetics against tetanus toxoid before and after primary vaccination of foals
Abstract Background Vaccination recommendations for foals against Clostridium tetani vary. Available studies assessing foal immune responses, maternal antibody interference, or individual variation often used small foal numbers. Objectives To quantify antibody responses after tetanus vaccination in foals and explore associations with passively ...
Katharina Olbrich +2 more
wiley +1 more source
NEDDylation is essential for Kaposi's sarcoma-associated herpesvirus latency and lytic reactivation and represents a novel anti-KSHV target. [PDF]
Kaposi's sarcoma-associated herpesvirus (KSHV) is the causative agent of Kaposi's sarcoma (KS) and primary effusion lymphoma (PEL), which are aggressive malignancies associated with immunocompromised patients.
Wood, Jennifer J +19 more
core +1 more source

