Results 81 to 90 of about 601,137 (192)

Human Herpesvirus 6 Encephalomyelitis

Emerging Infectious Diseases, 2004
Jose Luis Soto-Hernandez, Eric Denes, Sylvie Ranger-Rogez   +2 more
doaj   +1 more source

Late Cytomegalovirus Infections After Allogeneic Hematopoietic Cell Transplant

American Journal of Hematology, Volume 101, Issue 8, Page 1828-1838, August 2026.
ABSTRACT Graft versus host disease (GVHD) prophylaxis with posttransplant cyclophosphamide (ptCY) and cytomegalovirus (CMV) prophylaxis with letermovir have changed the clinical epidemiology of CMV infection. We studied the incidence, risk factors for, and outcomes of CMV infection after Day + 90 of allogeneic hematopoietic cell transplant (alloHCT ...
George L. Chen, Roland Bassett, Rohtesh S. Mehta, Betul Oran, Fareed Khawaja, Ella J. Ariza‐Heredia, Yosra Aljawai, Amanda Olson, May Daher, Portia Smallbone, Katayoun Rezvani, Partow Kebriaei, Uday Popat, Richard Champlin, Roy F. Chemaly, Elizabeth J. Shpall   +15 more
wiley   +1 more source

Clinical‐Stage Nanatinostat Triggers Productive Epstein‐Barr Virus Lytic Replication

Journal of Medical Virology, Volume 98, Issue 8, August 2026.
ABSTRACT A phase 1b/2 study of the all‐oral “kick‐and‐kill” combo nanatinostat + valganciclovir (nana‐val) showed a ~40% overall response rate in patients with relapsed/refractory Epstein‐Barr virus (EBV)‐associated lymphomas. Despite the promising results in these difficult‐to‐treat cancers, there is little known about the effects of nanatinostat on ...
Ibukun A. Akinyemi, Travis M. Zeigler, Griffin H. Willman, Devshree Patel, Ayman El‐Guindy, Michael T. McIntosh, Sumita Bhaduri‐McIntosh   +6 more
wiley   +1 more source

A Snapshot of the UK Blood Donor Plasma Virome: A Retrospective Cross‐Sectional Cohort Study

Journal of Medical Virology, Volume 98, Issue 8, August 2026.
ABSTRACT Estimates of population prevalence and genetic diversity of bloodborne viruses in healthy humans are essential to support population‐scale monitoring for transfusion transmission risk. In the UK and globally, blood donations are routinely screened for a limited number of high‐consequence pathogens, but the full composition of the plasma virome
Kai Kean, Richard M. Mayne, Kaitlin Reid, Shannah Secret, Belinda K. Singleton, Rebecca Rockett, Piya Rajendra, Heli Harvala, Judith Breuer, M. Azim Ansari, Katrina Lythgoe, Peter Simmonds, Tanya Golubchik   +12 more
wiley   +1 more source

Associations of Inherited Chromosomally‐Integrated Human Herpesvirus 6 With Dementia Incidence, Inflammation, and Other Dementia Risk Factors in the UK Biobank

Journal of Medical Virology, Volume 98, Issue 8, August 2026.
ABSTRACT The infection theory of dementia states that viral infections and chronic inflammation play a role in its pathogenesis. We aimed to test whether testing positive for inherited chromosomally‐integrated human herpesvirus 6 (iciHHV‐6) is associated with an increased dementia incidence, inflammation, and other dementia risk factors. We included n =
Zhong Qiya, Marko Mandic, Tim Waterboer, Xie Ruijie, Hermann Brenner, Ben Schöttker   +5 more
wiley   +1 more source

Manufacturing and clinical applications of non‐CAR‐T immune effector cells

Transfusion, EarlyView.
Thane Kubik, Theodros Mamo, David H. McKenna   +2 more
wiley   +1 more source

Recent Advances in the Molecular Mechanisms of Bacterial Anti‐Phage Defence Systems

Microbial Biotechnology, Volume 19, Issue 8, August 2026.
Panoptes as an example for an antiphage system consists of OptS producing a cyclic dinucleotide that prevents activation of OptE, a transmembrane protein. Phage T4 infection introduces the sponge protein Acb2 that adsorbs the cyclic dinucleotide thus activating OptE which disrupts the cell membrane aborting phage infection.
Harald Brüssow
wiley   +1 more source

Chemokines in Alzheimer's Disease: Early Defence, Late Damage and the Impact of Sex and Infection

Basic &Clinical Pharmacology &Toxicology, Volume 139, Issue 2, August 2026.
ABSTRACT Chemokines constitute a versatile signalling network maintaining homeostasis and glia–neuron communication in the healthy brain but become progressively dysregulated during aging and Alzheimer's disease (AD). This review examines how chemokine systems transition from tightly regulated homeostatic signals to drivers of chronic neuroinflammation
Blanca I. Aldana, Kristine Freude
wiley   +1 more source

Human herpesvirus 6 infection mimicking measles: two pediatric cases

The Turkish Journal of Pediatrics, 2015
Measles is a highly contagious viral infection associated with clinical symptoms such as fever, cough, conjunctivitis, coryza, eruption and increased serum immunoglobulin M (IgM) antibodies.
Masahide Goto, Hideki Kumagai, Ryou Kawamata, Shizuko Matsumoto, Miki Watanabe, Yasuyuki Nozaki   +5 more
doaj  

Chromosomal Integration of HHV-6 in a Preterm Neonate: A Rare Case of Hyperleukocytosis and Clinical Implications

Pediatric Reports
Leukocytosis in neonates can occur because of infectious, inflammatory, malignant, or physiological processes. Hyperleukocytosis is defined as a total leukocyte count (TLC) exceeding 100,000 per mm3, warranting immediate evaluation.
Palanikumar Balasundaram, Mohamed Sakr
doaj   +1 more source