Results 31 to 40 of about 85,704,137 (197)

Heterogeneity of viral IL-6 expression in HHV-8-associated diseases. [PDF]

, 2007
In order to characterize the expression of the viral interleukin-6 (vIL-6) homologue in various human herpesvirus 8 (HHV-8)-associated diseases, in situ hybridization and immunohistochemistry were applied to formalin-fixed specimens.
Cesarman, Ethel, Nicholas, John, Cannon, Jennifer S., Murray, Paul G., Ambinder, Richard F., Orenstein, Jan M., Mann, Risa B., DiGiuseppe, Joseph A., Hayward, Gary S., Browning, Philip J.   +9 more
core   +1 more source

Dendritic cells: Key players in human herpesvirus 8 infection and pathogenesis

Frontiers in Microbiology, 2014
Human herpesvirus 8 (HHV-8; Kaposi’s sarcoma-associated herpesvirus) is an oncogenic gammaherpesvirus that primarily infects cells of the immune and vascular systems.
Diana M. Campbell, Giovanna eRappocciolo, Frank J. Jenkins, Frank J. Jenkins, Charles R. Rinaldo, Charles R. Rinaldo   +5 more
doaj   +1 more source

Patterns of Human Herpesvirus-8 Oral Shedding among Diverse Cohorts of Human Herpesvirus-8 Seropositive Persons [PDF]

, 2016
Human herpesvirus-8 (HHV-8), the etiologic agent of Kaposi sarcoma (KS), establishes lifelong latent infection with periodic lytic replication (“shedding”) at mucosal sites, especially the oropharynx.
Johnston, Christine, Magaret, Amalia S, Schiffer, Joshua, Bender Ignacio, Rachel A, Goldman, Jason D, Huang, Meei-Li, Phipps, Warren, Selke, Stacy, Zuckerman, Richard, Gantt, Soren   +9 more
core   +3 more sources

Prevalence of human herpesviruses in biliary fluid and their association with biliary complications after liver transplantation

BMC Gastroenterology, 2019
Background Beta-herpesviruses are common opportunistic pathogens that cause morbidity after liver transplantation (LT). Methods Objective of the study was to evaluate the prevalence and correlation of herpesviruses in bile, blood and liver tissue and to ...
Conrad Rauber, Katja Bartelheimer, Taotao Zhou, Christian Rupp, Paul Schnitzler, Peter Schemmer, Peter Sauer, Karl Heinz Weiss, Daniel Nils Gotthardt   +8 more
doaj   +1 more source

Peroxisomes support human herpesvirus 8 latency by stabilizing the viral oncogenic protein vFLIP via the MAVS-TRAF complex. [PDF]

PLoS Pathogens, 2018
Human herpesvirus 8 (HHV-8) is causally related to human malignancies. HHV-8 latent viral FLICE-inhibitory protein (vFLIP) is a viral oncoprotein that is linked to pathogenesis, but how its expression is regulated is largely unknown.
Young Bong Choi, Yeeun Choi, Edward William Harhaj   +2 more
doaj   +1 more source

Kaposi Sarcoma in Afghanistan: A Case Series from a Tertiary Referral Center

Dermatopathology, 2022
Kaposi sarcoma is a vascular endothelial neoplasm caused by human herpesvirus 8. Although it is a well-studied disease, little is known about the specific characteristics or epidemiology of Kaposi sarcoma in Afghanistan.
Alyssa D. Higgins, Richard J. Dunn, Omer Malikzai, Mirwais Ahmadzai, Jerad M. Gardner, Benjamin K. Stoff, Josette R. McMichael   +6 more
doaj   +1 more source

Endemic Kaposi sarcoma in HIV-negative children and adolescents: an evaluation of overlapping and distinct clinical features in comparison with HIV-related disease

Infectious Agents and Cancer, 2018
Background Endemic Kaposi sarcoma (KS) was first described in African children over fifty years ago, but has recently been overshadowed by HIV-related disease.
Nader Kim El-Mallawany, Jimmy Villiera, William Kamiyango, Erin C. Peckham-Gregory, Michael E. Scheurer, Carl E. Allen, Casey L. McAtee, Alejandra Legarreta, Dirk P. Dittmer, Carrie L. Kovarik, Elizabeth Y. Chiao, Stephen C. Martin, Nmazuo W. Ozuah, Parth S. Mehta, Peter N. Kazembe   +14 more
doaj   +1 more source

HHV-8-Associated Lymphoproliferative Disorders and Pathogenesis in an HIV-Positive Patient

Case Reports in Hematology, 2019
Human herpesvirus 8 (HHV-8), also known as Kaposi’s sarcoma-associated herpesvirus, is a DNA oncovirus known for its role in the development of Kaposi’s sarcoma (KS) and several lymphoproliferative disorders (LPDs). HHV-8 promotes lymphoproliferation via
Carlo Guerrero, Tania Jain, Katalin Kelemen   +2 more
doaj   +1 more source

Seroprevalence of Kaposi sarcoma-associated herpesvirus and other serologic markers in the Brazilian Amazon. [PDF]

, 2009
To determine the presence of Kaposi sarcoma-associated herpesvirus (KSHV) and other serologic markers, we tested serum specimens of 339 Amerindians, 181 rural non-Amerindians, and 1,133 urban blood donors (13 Amerindians) in the Brazilian Amazon.
Mascheretti, Melissa, Laura M. Sumita, Nascimento, Maria C, SUMITA, Laura M., Weiss, Helen A, NASCIMENTO, Maria C., Maria C. Nascimento, Sabino, Ester, Souza, Vanda U, VELA, Rodrigo A. R., Quiroga, Mariana, Melissa Mascheretti, SOUZA, Vanda U., PANNUTI, Claudio S., Mariana Quiroga, Vela, Rodrigo AR, Helen A. Weiss, Nuno R. Faria, Vanda U. Souza, Pannuti, Claudio S, Mayaud, Philippe, Rodrigo A.R. Vela, Sumita, Laura M, Oliveira, Juliane, Juliane Oliveira, Philippe Mayaud, Claudio S. Pannuti, WEISS, Helen A.   +27 more
core   +1 more source

Human Herpesvirus 8 Induces Polyfunctional B Lymphocytes That Drive Kaposi’s Sarcoma

mBio, 2014
Kaposi’s sarcoma (KS) is an unusual neoplasia wherein the tumor consists primarily of endothelial cells infected with human herpesvirus 8 (HHV-8; Kaposi’s sarcoma-associated herpesvirus) that are not fully transformed but are instead driven to excess ...
Emilee R. Knowlton, Giovanna Rappocciolo, Paolo Piazza, Lauren M. Lepone, Sagar V. Nadgir, Arlene Bullotta, Stella J. Berendam, Jun Li, Todd A. Reinhart, Frank J. Jenkins, Charles R. Rinaldo   +10 more
doaj   +1 more source