Results 101 to 110 of about 9,697,114 (241)
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Human identification at a distance using iris and face [PDF]
This research has successfully applied super-resolution and multiple modality fusion techniques to address the major challenges of human identification at a distance using face and iris.
Nguyen Thanh, Kien
core
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Assessing the accuracy of the program Stature for stature estimation in White South Africans
In 2016, Polcerová and Králik created an open-access software program, Stature, designed to automate the estimation of living stature in forensic and archaeological cases.
Natasha R. Loubser +2 more
doaj +1 more source
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Anatomical and functional asymmetry predicts G-force tolerance in high-Intensity physical performers
Anatomical asymmetry is known to affect motor control and postural stability, but its impact under extreme physical stress, such as gravitational acceleration, remains underexplored.
Kyu-Lim Lee, Jun-Young Sung, Hee-Jin Kim
doaj +1 more source
Detection of Rehabilitation Training Effect of Upper Limb Movement Disorder Based on MPL-CNN
Stroke represents a medical emergency and can lead to the development of movement disorders such as abnormal muscle tone, limited range of motion, or abnormalities in coordination and balance. In order to help stroke patients recover as soon as possible,
Lijuan Shi +4 more
doaj +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Identification of the human factors contributing to maintenance failures in a petroleum operation
Structured interviews (N=38) were conducted with maintainers in a petroleum company who were asked to discuss a maintenance failure with which they were familiar.
Ari Antonovsky +7 more
core +1 more source

