Results 41 to 50 of about 443,339 (310)

Safety and practicality of an excisional lymph node study driving HIV cure research in South Africa

Frontiers in Immunology
IntroductionStudying diseased human tissues offers better insights into the intricate interactions between pathogens and the human host. In conditions such as HIV and cancers, where diseases primarily manifest in tissues, peripheral blood studies are ...
Trevor Khaba, Andrea Olga Papadopoulos, Thandeka Nkosi, Sifundo Nxele, Thandekile Ngubane, Ismail Jajbhay, Johan Pansegrouw, Zaza M. Ndhlovu, Zaza M. Ndhlovu, Zaza M. Ndhlovu   +9 more
doaj   +1 more source

Simian immunodeficiency virus (SIV) molecular epidemiology in non-human primates from West Africa [PDF]

, 2008
It is now scientifically proved that the human immunodeficiency viruses, HIV-1 and HIV-2, are the results of cross-species transmissions of the simian immunodeficiency viruses (SIV) that naturally infect non-human primates in sub- Saharan Africa ...
Locatelli, Sabrina
core   +1 more source

A literature review on cardiovascular risk in human immunodeficiency virus-infected patients: implications for clinical management

Brazilian Journal of Infectious Diseases, 2013
INTRODUCTION: In recent years, there has been growing concern about an increasing rate of cardiovascular diseases in human immunodeficiency virus-infected patients, which could be associated with side effects of highly active antiretroviral therapy.
Mansueto Gomes Neto, Ricardo Zwirtes, Carlos Brites   +2 more
doaj   +3 more sources

The burden of sepsis in critically ill human immunodeficiency virus-infected patients—a brief review

Brazilian Journal of Infectious Diseases, 2015
Since the advent of highly active antiretroviral therapy in 1996, we have seen dramatic changes in morbi-mortality rates from human immunodeficiency virus-positive patients.
José Moreira
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Hepatic peroxisome proliferator-activated receptor γ and α-mRNA expression in HCV-infected adults is decreased by HIV co-infection and is also affected by ethnicity

Clinics, 2015
OBJECTIVE: To determine peroxisome proliferator activated receptor α and γ mRNA expression in liver tissue of hepatitis C virus-infected patients with and without human immunodeficiency virus and its possible contribution to an acceleration of liver ...
Nathan J. Shores, Maria Cássia Mendes-Corrêa, Ivana Maida, JoLyn Turner, Kevin P. High, Sergio Babudieri, Marina Núãez   +6 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Epidemiology and interactions of Human Immunodeficiency Virus - 1 and Schistosoma mansoni in sub-Saharan Africa. [PDF]

, 2013
Human Immunodeficiency Virus-1/AIDS and Schistosoma mansoni are widespread in sub-Saharan Africa and co-infection occurs commonly. Since the early 1990s, it has been suggested that the two infections may interact and potentiate the effects of each other ...
Nuwaha, Fred, Heukelbach, Jorg, Shona Wilson, Jorg Heukelbach, Fred Nuwaha, Safari M Kinung'hi, Morona, Domenica, Dunne, David W, Mazigo, Humphrey D., Dunne, David W., Kinung'hi, Safari M., Domenica Morona, David W Dunne, Kinung'hi, Safari M, Rebecca Waihenya, Mazigo, Humphrey D, Wilson, Shona, Waihenya, Rebecca, Humphrey D Mazigo   +18 more
core   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Strong correlation by ultrasonography of hepatomegaly and the presence of co-infection in HIV/HCV cirrhotic patients

Brazilian Journal of Infectious Diseases, 2013
OBJECTIVES: Progression of hepatic fibrosis is accelerated in patients co-infected with human immunodeficiency virus and hepatitis C virus compared to hepatitis C virus mono-infected patients.
Denise Cerqueira Paranaguá Vezozzo, Maria Cassia Mendes-Correa, Marlone Cunha-Silva, Mónica Viviana Alvarado-Mora, João Ítalo Dias França, José Luiz Sebba, Antonio Carlos Nicodemo, Claudia P.M.S. Oliveira, Flair José Carrilho   +8 more
doaj   +3 more sources