Results 41 to 50 of about 681,627 (391)
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein
FEBS Open Bio, EarlyView.Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley +1 more source
Low uptake of antiretroviral therapy after admission with human immunodeficiency virus and tuberculosis in KwaZulu-Natal, South Africa. [PDF]
, 2010 A prospective cohort study was conducted among human immunodeficiency virus (HIV) infected in-patients with tuberculosis (TB) or other opportunistic infections (OIs) in South Africa to estimate subsequent antiretroviral therapy (ART) uptake and ...
Kappagoda, S +6 more
core +1 more source
FEBS Open Bio, EarlyView.The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer +7 more
wiley +1 more source
EPIDEMIOLOGICAL ASPECTS OF THE INCIDENCE OF HIV INFECTION IN THE RUSSIAN FEDERATION AND KUZBASS
Медицина в Кузбассе, 2022 Human immunodeficiency virus (HIV infection) is one of the most severe non-epidemic and socially caused infectious diseases worldwide. HIV infection is an infectious anthroponotic chronic disease caused by the human immunodeficiency virus, slowly ...
Андрей Георгиевич Петров +5 more
doaj
Brazilian Journal of Infectious Diseases, 2013 Objective: To evaluate the influence of hepatitis C virus on immunological and virological responses after highly active antiretroviral therapy initiation in human immunodeficiency virus/hepatitis C virus coinfected patients compared to monoinfected ...
Vicente Sperb Antonello +4 more
doaj +1 more source
Immunity to Human Immunodeficiency Virus (HIV) Infection [PDF]
Clinical and Developmental Immunology, 2012 The advent of highly active antiretroviral therapy (HAART) in 1996 revolutionized life expectancy and quality of life of people infected by HIV in the developed Countries. Nowadays, HIV-infected patients can positively think that their life expectancy is comparable to that of people of the same age and with the same pattern of risk factors Indeed ...
Torti, C, Paiardini, M, GORI, ANDREA
openaire +6 more sources
CD4+ T Cell Depletion in Human Immunodeficiency Virus (HIV) Infection: Role of Apoptosis
Viruses, 2011 Human immunodeficiency virus (HIV) infection is principally a mucosal disease and the gastrointestinal (GI) tract is the major site of HIV replication. Loss of CD4+ T cells and systemic immune hyperactivation are the hallmarks of HIV infection.
M. Février, K. Dorgham, A. Rebollo
semanticscholar +1 more source
CX3CL1 in Early Detection of Alzheimer's Disease: Plasma Dynamics Across Age and Disease Stages
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Backgrounds Alzheimer's disease (AD) is characterized by amyloid‐beta plaques, tau tangles, and neuroinflammation. C‐X3‐C motif chemokine ligand 1 (CX3CL1, also known as fractalkine), a neuroimmune chemokine implicated in AD pathogenesis, shows inconsistent alterations in plasma/serum across studies.
Ling Wang +6 more
wiley +1 more source
Patterns of HIV/SIV prevention and control by passive antibody immunization
Frontiers in Microbiology, 2016 Neutralizing antibody (NAb) responses are promising immune effectors for control of human immunodeficiency virus (HIV) infection. Protective activity and mechanisms of immunodeficiency virus-specific NAbs have been increasingly scrutinized in animals ...
Hiroyuki Yamamoto +2 more
doaj +1 more source