Results 201 to 210 of about 5,646,240 (252)
FEBS Open Bio, EarlyView.Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold +11 more
wiley +1 more source
FEBS Open Bio, EarlyView.A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li +6 more
wiley +1 more source
FEBS Open Bio, EarlyView.Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li +8 more
wiley +1 more source
FEBS Open Bio, EarlyView.ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand +2 more
wiley +1 more source
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2021
Coastal soft sediments are closely linked to human activity both on the land and at sea and consequently they are subjected to a wide array of human impacts. Looking for some general patterns in the consequences of impacts, this chapter identifies a range of different ecological changes as a result of direct impacts and then moves to address indirect ...
Simon F. Thrush +3 more
openaire +1 more source
Coastal soft sediments are closely linked to human activity both on the land and at sea and consequently they are subjected to a wide array of human impacts. Looking for some general patterns in the consequences of impacts, this chapter identifies a range of different ecological changes as a result of direct impacts and then moves to address indirect ...
Simon F. Thrush +3 more
openaire +1 more source
1992
Abstract Environmental change spans all of human time. Even so-called primitive peoples have left their mark on the earth. Fire, the oldest of anthropogenic landscape modifiers, has long been implicated in the origins and maintenance of tropical savannahs and mid-latitude grasslands, and biggame hunters of the Stone Age may have caused ...
S Robert Aiken, Colin H Leigh
openaire +1 more source
Abstract Environmental change spans all of human time. Even so-called primitive peoples have left their mark on the earth. Fire, the oldest of anthropogenic landscape modifiers, has long been implicated in the origins and maintenance of tropical savannahs and mid-latitude grasslands, and biggame hunters of the Stone Age may have caused ...
S Robert Aiken, Colin H Leigh
openaire +1 more source
Science
Behind the myriad upheavals U.S. science has faced during the first 100 days of President Donald Trump’s administration, countless researchers are fighting for their careers and aspirations.
Sara, Reardon +3 more
openaire +2 more sources
Behind the myriad upheavals U.S. science has faced during the first 100 days of President Donald Trump’s administration, countless researchers are fighting for their careers and aspirations.
Sara, Reardon +3 more
openaire +2 more sources
1985
The fundamental role of climate for the fate of mankind is increasingly being recognized at both the international and national levels (World Meteorological Organization, 1980, pp. 7–10, 28–37; World Meteorological Organization-ICSU, 1975, pp. 1–3; United Nations Environment Programme, 1979, pp. 1–16; National Climate Program Office NOAA, 1980, pp. 1–4,
openaire +1 more source
The fundamental role of climate for the fate of mankind is increasingly being recognized at both the international and national levels (World Meteorological Organization, 1980, pp. 7–10, 28–37; World Meteorological Organization-ICSU, 1975, pp. 1–3; United Nations Environment Programme, 1979, pp. 1–16; National Climate Program Office NOAA, 1980, pp. 1–4,
openaire +1 more source
Impact of the Microbiome on the Human Genome
Trends in Parasitology, 2019Humans live in a microbial world that includes pathogenic bacteria, viruses, and fungi that cause lethal infections. In addition, a large number of microbial communities inhabit mucosal surfaces where they provide key metabolic activities, facilitating adaptation to changing environments.
Thiviya, Jeyakumar +2 more
openaire +2 more sources