Results 21 to 30 of about 8,123,417 (252)

Testing positive for human papillomavirus in routine cervical screening: examination of psychosocial impact [PDF]

, 2004
Objective To examine the psychosocial impact of testing positive for high risk human papillomavirus (HPV) among women attending primary cervical screening.Design Cross sectional survey.Measures were taken at baseline and one week after the receipt of HPV
Cadman, L, Forrest, S, McCaffery, K, Szarewski, A, Waller, J, Wardle, J   +5 more
core   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Impact of human resource management information systems on the quality of appraisal performance process [PDF]

, 2013
Copyright @ 2013 EMCIS.These days the recent development of information systems and their impact on human resource activities is one of the main hot debates in many large organizations.
Al-Karaghouli, W, Khan, T, Pouransari, S
core  

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Assessing humanity’s global impact [PDF]

Current Biology, 2015
SummaryAn official committee now ponders the question of whether human impacts have derailed the Earth system sufficiently to declare the beginning of a new geological epoch, the Anthropocene. Meanwhile, researchers have updated and improved two influential assessments of our global status, namely the ‘planetary boundaries’ and the ‘great acceleration’
openaire   +2 more sources

Biallelic Inactivation of NSD1 Associated With Carcinogenesis in Sotos Syndrome

Pediatric Blood &Cancer, EarlyView.
Nicholas A. Borja, Anuja Sule, Katie Ann McMullen, Aditi Dhir, Matthew D. Hall, Heather J. McCrea, Sakir Humayun Gultekin, Mustafa Tekin, Bradley Gampel   +8 more
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Corporate Social Responsibility in the Management of Human and Environmental Resources: Andalucian Perspectives [PDF]

, 2019
There are a number of objectives that guide this work. First, we aimed to identify the general characteristics of Andalusian companies in terms their approach to social responsibility, particularly in the area of human resources and environmental impact.
Aguilera, Bessire, Bowen, Carroll, Castellanos-Verdugo, Cuesta, Cuesta, Dunphy, Fombrun, Fuentes, Hinton, Kotler, Melé, Munuera-Alemán, Nicholls, Nunnally, Payno, Porter, Post, Schvarstein, Selznick, Smith, Vargas, Velarde, Vogel   +24 more
core   +2 more sources

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source