Results 101 to 110 of about 18,809,909 (341)

The role and implications of mammalian cellular circadian entrainment

FEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

Hydrology, plankton, and corals of the Maracajaú reefs (Northeastern Brazil): an ecosystem under severe thermal stress

Brazilian Archives of Biology and Technology, 2009
This study provides baseline information on the hydrological conditions and on the coral and plankton communities at the Maracajaú reef ecosystem (Northeastern Brazil).
Elga Miranda Mayal, Sigrid Neumann-Leitão, Fernando Antônio do Nascimento Feitosa, Ralf Schwamborn, Tâmara de Almeida e Silva, Maria da Glória Gonçalves da Silva-Cunha   +5 more
doaj   +1 more source

First human impacts and responses of aquatic systems: A review of palaeolimnological records from around the world

, 2018
Lake sediments constitute natural archives of past environmental changes. Historically, research has focused mainly on generating regional climate records, but records of human impacts caused by land use and exploitation of freshwater resources are now ...
N. Dubois, Émilie Saulnier‐Talbot, Keely Mills, P. Gell, R. Battarbee, H. Bennion, S. Chawchai, Xuhui Dong, P. Francus, R. Flower, D. F. Gomes, I. Gregory‐Eaves, S. Humane, G. Kattel, J. Jenny, P. Langdon, J. Massaferro, S. McGowan, A. Mikomägi, N. Ngoc, A. S. Ratnayake, M. Reid, N. Rose, J. Saros, D. Schillereff, M. Tolotti, B. Valero-Garcés   +26 more
semanticscholar   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

FEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Impacts of Climate Change on indirect human exposure to pathogens and chemicals from agriculture [PDF]

, 2008
Objective: Climate change is likely to affect the nature of pathogens and chemicals in the environment and their fate and transport. Future risks of pathogens and chemicals could therefore be very different from those of today.
Adhikari A, Alistair B.A. Boxall, Anthony Hardy, David B. Turley, David Stone, Edward Topp, Elizabeth M.H. Wellington, European Communities, Food and Agriculture Organization, Gale P, Giovanni Leonardi, Githecko AK, Gordon Nichols, Haines A, Hawkes C, Kerry Walsh, Laura Burgin, Laura Potts, Leonard S. Levy, Patterson DT, Peter D. Falloon, Philip M. Haygarth, R. Sari Kovats, Richard J. Williams, Sabine Beulke, Simon A. Parsons, Tatiana Boucard, Thomas Hutchinson, van den Berg H   +28 more
core   +6 more sources

Using human genetics to understand the disease impacts of testosterone in men and women

Nature Medicine, 2020
Testosterone supplementation is commonly used for its effects on sexual function, bone health and body composition, yet its effects on disease outcomes are unknown.
K. Ruth, F. Day, J. Tyrrell, Deborah J. Thompson, A. Wood, A. Mahajan, R. Beaumont, L. Wittemans, L. Wittemans, S. Martin, Alexander S. Busch, Alexander S. Busch, A. Erzurumluoglu, Benjamin Hollis, T. O’Mara, M. McCarthy, C. Langenberg, D. Easton, N. Wareham, S. Burgess, A. Murray, Ken K. Ong, Ken K. Ong, T. Frayling, J. Perry   +24 more
semanticscholar   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

On the use of anthropogenic materials in nest building of House Wren (Troglodytes aedon), a report from Parque Los Algarrobos, Cumbayá, Ecuador

ACI Avances en Ciencias e Ingenierías
Urbanization has prompted shifts in avian nesting behaviors, with some bird species incorporating anthropogenic nest materials (ANMs) into their nests.
Mateo Davila, Roberto J. León-E., Ariel Guerrero-Campoverde   +2 more
doaj   +1 more source

Estimating the soil subsidence and carbon losses from long term anthropogenic use of peatlands: A case study on a Danish raised bog [PDF]

Mires and Peat
Upon drainage, peatlands subside and release stored carbon (C) into the atmosphere. However, little is known about the magnitude of the total, physical and oxidative subsidence (TS, PS and OS) over long historical periods and the past contribution of ...
Diana V. Adetsu, Triven Koganti, Rasmus J. Petersen, Dominik Zak, Ida-Emile F. Nilsson, Carl C. Hoffman, Amélie Beucher, Mogens H. Greve   +7 more
doaj   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

FEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang, Grace Du, Charity Yongo‐Luwawa, Angelina Lu, Brett Kinrade, Kim Munro, Karl E. Klose, William D. Lubell, Peter Davies, Shuaiqi Guo   +9 more
wiley   +1 more source