Results 151 to 160 of about 18,809,909 (341)
Mitigating Human Impacts on Wild Animal Welfare. [PDF]
Animals (Basel), 2023 Macdonald DW.
europepmc +1 more source
Climate Change and Economic Growth: Impacts and Interactions [PDF]
An integrated assessment model (ENVISAGE), including a CGE-based economic module and a climate module, is used to assess the effects of a variety of economic impacts induced by climate change.
Dominique van der Mensbrugghe
core
Discharge Characteristics and Changes over the Ob River Watershed in Siberia [PDF]
, 2004 This study analyzes long-term (1936–90) monthly streamflow records for the major subbasins within the Ob River watershed in order to examine discharge changes induced by human activities (particularly reservoirs and agricultural activities) and natural ...
Shiklomanov, Alexander I. +2 more
core +2 more sources
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
Human resources impact assessment.
Bulletin of the World Health Organization, 2003 Has been published before in: Bull.
Van Lerberghe, W. +2 more
openaire +3 more sources
Molecular Oncology, EarlyView.AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
HoehneaNosso objetivo foi revisar o papel ecológico das trilhas e inserir essa temática nos projetos de restauração ecológica. Para uma compreensão abrangente desse papel ecológico, abordamos tanto as possíveis aplicações das trilhas para projetos de Educação ...
Pedro Vasconcellos Eisenlohr +7 more
doaj +1 more source
Fate Control and Human Rights: The Policies and Practices of Local Governance in America's Arctic [PDF]
, 2014 The loss of territoriality over lands conveyed under the Alaska Native Claims Settlement Act had adverse impacts for Alaskan tribal governance. Despite policy frameworks that emphasize the value of local governance at an international, regional, and ...
Kimmel, Mara
core +1 more source
Molecular Oncology, EarlyView.PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source