Results 171 to 180 of about 18,809,909 (341)
Emerging role of ARHGAP29 in melanoma cell phenotype switching
Molecular Oncology, EarlyView.This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster +3 more
wiley +1 more source
Markets for Anthropogenic Carbon Within the Larger Carbon Cycle [PDF]
Human activity has disrupted the natural balance of greenhouse gases in the atmosphere and is causing climate change. Burning fossil fuels and deforestation result directly in about 9 gigatons of carbon (GtC) emissions per year against the backdrop of ...
Borenstein, Severin
core +1 more source
African coastal camera network efforts at monitoring ocean, climate, and human impacts. [PDF]
Sci Rep, 2023 Abessolo GO +17 more
europepmc +1 more source
The inter-linkages between rapid growth in livestock production, climate change, and the impacts on water resources, land use, and deforestation [PDF]
Livestock systems globally are changing rapidly in response to human population growth, urbanization, and growing incomes. This paper discusses the linkages between burgeoning demand for livestock products, growth in livestock production, and the impacts
Herrero, Mario, Thornton, Philip K.
core
Molecular Oncology, EarlyView.In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern +7 more
wiley +1 more source
Human impacts on mammals in and around a protected area before, during, and after COVID-19 lockdowns. [PDF]
Conserv Sci Pract, 2022 Procko M, Naidoo R, LeMay V, Burton AC.
europepmc +1 more source
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
Precipitation, vegetation productivity, and human impacts control home range size of elephants in dryland systems in northern Namibia. [PDF]
Ecol Evol, 2022 Benitez L +7 more
europepmc +1 more source
Molecular Oncology, EarlyView.This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert +13 more
wiley +1 more source
Latin America and the global climate change
RUDN Journal of Ecology and Life Safety, 2012 Based on the spatial mathematical model of global carbon dioxide cycle in the biosphere calculated absorption of carbon dioxide emissions from the burning of fossil fuels, including deforestation and soil erosion in Latin America and the world ...
A M Tarko +3 more
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