Results 101 to 110 of about 293,069 (216)

Targeting the ARRDC3–DRP1 Axis via hUMSC‐Derived Exosomal CRYAB for Neuroprotection in Cerebral Ischemia/Reperfusion Injury

Advanced Healthcare Materials, EarlyView.
Intranasally administered hUMSC‐derived exosomes modulate the CRYAB–ARRDC3–Drp1 axis, alleviating mitochondrial dysfunction and ferroptosis, enhancing neuronal survival, reducing oxidative stress, and promoting functional recovery in ischemia‐reperfusion injury, offering a promising therapeutic strategy for ischemic stroke.
Rong ji, Zengyu Zhang, Zhuohang Liu, Kaicheng Yang, Xueyu Mao, Min Chu, Yong Wang, Jing Zhao   +7 more
wiley   +1 more source

Boron‐Doped Nano‐Crystalline Coated Carbon Fibers for Phasic Dopamine Sensing

Advanced Healthcare Materials, EarlyView.
This uniform coating presents a mix of graphitic and diamond‐like carbon to create a mechanically and electrically robust alternative for the electrochemical detection of dopamine. The electrodes in this work possess the equivalent sensitivity to the state‐of‐the‐art FSCV dopamine detecting electrodes, whilst demonstrating an ability to withstand ...
Simon J. Higham, Juan M. Rojas Cabrera, Youngjong Kwak, Lydia Hong, Andre Chambers, Athavan Nadarajah, Sorel E. De Leon, Young Jun Jung, Negin Jalilinejad, Charles Blaha, Dong Pyo Jang, Yoonbae Oh, Kendall Lee, Alastair Stacey, Shaun L. Cloherty, Michael R. Ibbotson, David J. Garrett, Steven Prawer, Hojin Shin, Wei Tong   +19 more
wiley   +1 more source

We are underestimating, again, the true burden of H5N1 in humans

BMJ Global Health, 2023
Mokhtar Gomaa, Yassmin Moatasim, Ahmed El Taweel, Sara H Mahmoud, Amira S El Rifay, Ahmed Kandeil, Pamela P McKenzie, Richard J Webby, Rabeh El-Shesheny, Mohamed Ahmed Ali, Ghazi Kayali   +10 more
doaj   +1 more source

Rapid detection of human influenza A viruses by HFman probe-based loop-mediated isothermal amplification assays. [PDF]

Heliyon, 2023
Zhao Y, Li B, Wan Z, Zeng Y, Zhang X, Tian W, Zhang C.   +6 more
europepmc   +1 more source

Simvastatin Restores Uteroplacental Hemodynamics and Trophoblast Function in Obstetric Antiphospholipid Syndrome in a Placenta‐on‐a‐Chip Model

Advanced Healthcare Materials, EarlyView.
Simvastatin mitigates placental hypoperfusion in OAPS by ameliorating abnormal uteromaternal hemodynamics and enhancing trophoblast invasion via optimized endothelial cell interactions under pathological shear stress, as evidenced by results from a placenta‐on‐a‐chip platform.
Hongli Liu, Yuan Wang, Yanjun Cai, Ruixin Guo, Shunhua Liu, Tingting Chen, Tingting Sun, Ruiheng Huo, Tengwei Liu, Qingfeng Lv, Xietong Wang   +10 more
wiley   +1 more source

Human Influenza Epidemiology. [PDF]

Cold Spring Harb Perspect Med, 2021
Ryu S, Cowling BJ.
europepmc   +1 more source

Human Brain Vasculature‐on‐a‐Chip Model Constructed With Microvessels Isolated From Cryopreserved Postmortem Human Brain Tissue

Advanced Healthcare Materials, EarlyView.
This manuscript describes the cultivation of viable microvessels from cryopreserved human brain tissue. When embedded in hydrogels and cultured in microfluidic devices, these microvessels exhibit complex architectures reminiscent of arterioles and capillaries, can be perfused, and display intact barrier function. Collectively, these results demonstrate
Brian J. O'Grady, A. Scott McCall, Samuel Cullison, Daniel Chavarria, Matthew S. Schrag, Ethan S. Lippmann   +5 more
wiley   +1 more source

Author Correction: Transmission dynamics of avian influenza viruses in Egyptian poultry markets

npj Viruses
Sara H. Mahmoud, Mokhtar Gomaa, Ahmed El Taweel, Yassmin Moatasim, Mina Nabil Kamel, Mohamed El Sayes, Noura M. Abo Shama, Rebecca Badra, Mona Mahmoud, Pamela P. McKenzie, Richard J. Webby, Ahmed Kandeil, Mohamed Ahmed Ali, Rabeh El-Shesheny, Ghazi Kayali   +14 more
doaj   +1 more source

High-throughput neutralization measurements correlate strongly with evolutionary success of human influenza strains. [PDF]

Elife
Kikawa C, Loes AN, Huddleston J, Figgins MD, Steinberg P, Griffiths T, Drapeau EM, Peck H, Barr I, Englund JA, Hensley SE, Bedford T, Bloom JD.   +12 more
europepmc   +1 more source

INFINITy: A fast machine learning-based application for human influenza A and B virus subtyping. [PDF]

Influenza Other Respir Viruses, 2023
Cacciabue M, Marcone DN.
europepmc   +1 more source