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Pathogenicity of H9N2 low pathogenic avian influenza viruses of different lineages isolated from live bird markets tested in three animal models: SPF chickens, Korean native chickens, and ducks

Poultry Science, 2021
: Since its first appearance in 1996, H9N2 avian influenza virus (AIV) of the Y439 lineage persisted in Korean live bird markets (LBMs) until the last documented occurrence in 2018. However, in June 2020, the avian influenza surveillance program detected
Soo-Jeong Kye, Min-Ji Park, Na-Young Kim, Yu-Na Lee, Gyeong-Beom Heo, Yoon-Ki Baek, Jae-In Shin, Myoung-Heon Lee, Youn-Jeong Lee   +8 more
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Adsorptive mutation and N-linked glycosylation modulate influenza virus antigenicity and fitness

Emerging Microbes and Infections, 2020
Influenza viruses have an error-prone polymerase complex that facilitates a mutagenic environment. Antigenic mutants swiftly arise from this environment with the capacity to persist in both humans and economically important livestock even in the face of ...
Joshua E. Sealy, Thomas P. Peacock, Jean-Remy Sadeyen, Pengxiang Chang, Holly J. Everest, Sushant Bhat, Munir Iqbal   +6 more
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Single dose of multi-clade virus-like particle vaccine protects chickens against clade 2.3.2.1 and clade 2.3.4.4 highly pathogenic avian influenza viruses

Scientific Reports, 2021
Virus-like particles (VLPs) are recognized as an alternative vaccine platform that provide effective protection against various highly pathogenic avian influenza viruses (HPAIVs). Here, we developed multi-clade VLPs expressing two HAs (a chimera of clade
Yong-Myung Kang, Hyun-Kyu Cho, Ju Hun Kim, Su Jin Lee, Seo-Jeong Park, Do-Young Kim, Seong Yup Kim, Jung-won Park, Myoung-Heon Lee, Min-Chul Kim, Hyun-Mi Kang   +10 more
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Isolation and characterization of low pathogenic H7N7 avian influenza virus from a red-crowned crane in a zoo in South Korea

BMC Veterinary Research, 2020
Background South Korea conducts annual national surveillance programs to detect avian influenza (AI) in domestic poultry, live bird markets, and wild birds.
Young-Jae Si, Yu-Na Lee, Sun-Ha Cheon, Yu-Ri Park, Yoon-Gi Baek, Soo-Jeong Kye, Myoung-Heon Lee, Youn-Jeong Lee   +7 more
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Evolutionary Dynamics of H5 Highly Pathogenic Avian Influenza Viruses (Clade 2.3.4.4B) Circulating in Bulgaria in 2019–2021

Viruses, 2021
The first detection of a Highly Pathogenic Avian Influenza (HPAI) H5N8 virus in Bulgaria dates back to December 2016. Since then, many outbreaks caused by HPAI H5 viruses from clade 2.3.4.4B have been reported in both domestic and wild birds in different
Bianca Zecchin, Gabriela Goujgoulova, Isabella Monne, Annalisa Salviato, Alessia Schivo, Iskra Slavcheva, Ambra Pastori, Ian H. Brown, Nicola S. Lewis, Calogero Terregino, Alice Fusaro   +10 more
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Pathogenicity of H5N8 High Pathogenicity Avian Influenza Virus in Chickens and Ducks from South Korea in 2020–2021

Viruses, 2021
During the 2020–2021 winter season, an outbreak of clade 2.3.4.4b H5N8 high pathogenicity avian influenza (HPAI) virus occurred in South Korea. Here, we evaluated the pathogenicity and transmissibility of A/mandarin duck/Korea/H242/2020 (H5N8) (H242/20 ...
Min-Ji Park, Ra Mi Cha, Soo-Jeong Kye, Yu-Na Lee, Na-Yeong Kim, Yoon-Gi Baek, Gyeong-Beom Heo, Mingeun Sagong, Kwang-Nyeong Lee, Youn-Jeong Lee, Eun-Kyoung Lee   +10 more
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Experimental Infection and In-Contact Transmission of H9N2 Avian Influenza Virus in Crows

Pathogens, 2022
This study aimed to investigate the potential of H9N2 avian influenza virus to cause disease and intra-species transmission in house crows (Corvus splendens).
Asha Kumari Verma, Manoj Kumar, Harshad V. Murugkar, Shanmugasundaram Nagarajan, Chakradhar Tosh, Pushpendra Namdeo, Rupal Singh, Suman Mishra, Subbiah Kombiah, Senthilkumar Dhanapal, Vijendra Pal Singh   +10 more
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Genetic characteristics and pathogenesis of H5 low pathogenic avian influenza viruses from wild birds and domestic ducks in South Korea

Scientific Reports, 2020
H5 and H7 subtypes of low pathogenic avian influenza viruses (LPAIVs) can mutate to highly pathogenic forms and are therefore subject to stringent controls.
Yu-Na Lee, Dong-Hun Lee, Sun-Ha Cheon, Yu-Ri Park, Yoon-Gi Baek, Young-Jae Si, Soo-Jeong Kye, Eun-Kyoung Lee, Gyeong-Beom Heo, You-Chan Bae, Myoung-Heon Lee, Youn-Jeong Lee   +11 more
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Evolution, Transmission, and Pathogenicity of High Pathogenicity Avian Influenza Virus A (H5N8) Clade 2.3.4.4, South Korea, 2014–2016

Frontiers in Veterinary Science, 2022
During 2014–2016, clade 2.3.4.4 H5N8 high pathogenicity avian influenza virus (HPAIV) caused the largest known avian influenza epidemic in South Korea.
Yoon-Gi Baek, Yu-Na Lee, Yu-Ri Park, David H. Chung, Jung-Hoon Kwon, Young-Jae Si, Gyeong-Beom Heo, Youn-Jeong Lee, Dong-Hun Lee, Eun-Kyoung Lee   +9 more
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A Characterization and an Evolutionary and a Pathogenicity Analysis of Reassortment H3N2 Avian Influenza Virus in South China in 2019–2020

Viruses, 2022
Seasonal H3N2 influenza virus has always been a potential threat to public health. The reassortment of the human and avian H3N2 influenza viruses has resulted in major influenza outbreaks, which have seriously damaged human life and health. To assess the
Tengfei Liu, Yuhao Huang, Shumin Xie, Lingyu Xu, Junhong Chen, Wenbao Qi, Ming Liao, Weixin Jia   +7 more
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