Results 11 to 20 of about 63,325 (206)
The current epidemic of H5N1 highly pathogenic avian influenza in Southeast Asia raises serious concerns that genetic reassortment will result in the next influenza pandemic. There have been 164 confirmed cases of human infection with avian influenza since 1996.
Zeitlin, Gary Adam, Maslow, Melanie Jane
+12 more sources
A rapidly spreading, highly pathogenic avian influenza virus A H5N1 in the domestic poultry population has crossed the species barrier to humans and other mammalian species, thus, posing an increasing pandemic threat. The World Health Organization, other agencies, and countries worldwide are closely monitoring the prevalent influenza viruses and their ...
Awad A, Saeed, Mansour F, Hussein
+13 more sources
Previous introductions of highly pathogenic avian influenza virus (HPAIV) to the EU were most likely via migratory wild birds. A mathematical model has been developed which indicated that virus amplification and spread may take place when wild bird populations of sufficient size within EU become infected.
Health, EFSA Panel on Animal +35 more
openaire +9 more sources
The transmissibility of highly pathogenic avian influenza in commercial poultry in industrialised countries. [PDF]
BACKGROUND: With the increased occurrence of outbreaks of H5N1 worldwide there is concern that the virus could enter commercial poultry farms with severe economic consequences. METHODOLOGY/PRINCIPAL FINDINGS: We analyse data from four recent outbreaks of
Azra C Ghani +8 more
core +1 more source
Differential contribution of PB1-F2 to the virulence of highly pathogenic H5N1 influenza A virus in mammalian and avian species [PDF]
Highly pathogenic avian influenza A viruses (HPAIV) of the H5N1 subtype occasionally transmit from birds to humans and can cause severe systemic infections in both hosts.
García-Sastre, Adolfo +42 more
core +1 more source
Truncation of the NS1 protein converts a low pathogenic avian influenza virus into a strong interferon inducer in duck cells [PDF]
The NS1 protein of influenza A viruses is known as a nonessential virulence factor inhibiting type I interferon (IFN) production in mammals and in chicken cells. Whether NS1 inhibits the induction of type I IFNs in duck cells is currently unknown.
Guérin, Jean-Luc +3 more
core +1 more source
Since their reemergence in 2003, highly pathogenic avian influenza A (H5N1) viruses have reached endemic levels among poultry in several southeast Asian countries and have caused a still increasing number of more than 100 reported human infections with high mortality. These developments have ignited global fears of an imminent influenza pandemic.
Jong, d, Hien, T
openaire +2 more sources
Avian influenza is an important zoonotic disease that has become endemic in Southeast Asia and in the case of highly pathogenic H5N1 has caused significant human mortality and morbidity. Avian influenza virus (AIV) infections may be asymptomatic or present as mild conjunctivitis in humans; however, H5N1 infections may present as severe pneumonia ...
Sean, Adams, Christian, Sandrock
openaire +2 more sources
Influenza viruses are unique among respiratory viruses in exhibiting “drift,” which is change in surface antigens as a result of host immunological pressure. In addition, influenza A viruses exhibit “shift”—which is the genetic intermingling of human strains with animal or bird strains, resulting in completely new viruses of pandemic potential.
E, Walker, P, Christie
openaire +3 more sources
Discordant correlation between serological assays observed when measuring heterosubtypic responses against avian influenza H5 and H7 viruses in unexposed individuals [PDF]
The human population is constantly exposed to multiple influenza A subtypes due to zoonotic spill over and rapid viral evolution driven by intrinsic error-prone replication and immunological pressure.
Ferrara, Francesca +5 more
core +1 more source

