Results 31 to 40 of about 321,909 (259)

Application of HDR-CRISPR/Cas9 and Erythrocyte Binding for Rapid Generation of Recombinant Turkey Herpesvirus-Vectored Avian Influenza Virus Vaccines

Vaccines, 2019
Avian influenza viruses (AIVs) are highly contagious and have caused huge economical loss to the poultry industry. AIV vaccines remain one of the most effective methods of controlling this disease.
Pengxiang Chang, Faisal Ameen, Joshua E. Sealy, Jean-Remy Sadeyen, Sushant Bhat, Yongqing Li, Munir Iqbal   +6 more
doaj   +1 more source

That H9N2 avian influenza viruses circulating in different regions gather in the same live-poultry market poses a potential threat to public health

Frontiers in Microbiology, 2023
H9N2 avian influenza viruses are endemic and persistent in China, but those that are prevalent in different provinces are also causes of wide epidemics, related to the spread of wild birds and the cross-regional trade in live poultry.
Tengfei Liu, Shumin Xie, Zhiyi Yang, Aimin Zha, Yuting Shi, Lingyu Xu, Junhong Chen, Wenbao Qi, Wenbao Qi, Wenbao Qi, Ming Liao, Ming Liao, Ming Liao, Weixin Jia, Weixin Jia, Weixin Jia   +15 more
doaj   +1 more source

Truncation of the NS1 protein converts a low pathogenic avian influenza virus into a strong interferon inducer in duck cells [PDF]

, 2010
The NS1 protein of influenza A viruses is known as a nonessential virulence factor inhibiting type I interferon (IFN) production in mammals and in chicken cells. Whether NS1 inhibits the induction of type I IFNs in duck cells is currently unknown.
Guérin, Jean-Luc, Volmer, Christelle, Soubiès, Sébastien, Volmer, Romain   +3 more
core   +1 more source

Development of a duplex TaqMan real-time RT-PCR assay for simultaneous detection of newly emerged H5N6 influenza viruses

Virology Journal, 2019
Background In 2017–2018, a new highly pathogenic H5N6 avian influenza virus (AIV) variant appeared in poultry and wild birds in Asian and European countries and caused multiple outbreaks. These variant strains are different from the H5N6 virus associated
Lin Liu, Ying Zhang, Pengfei Cui, Congcong Wang, Xianying Zeng, Guohua Deng, Xiurong Wang   +6 more
doaj   +1 more source

Novel sialic acid derivatives lock open the 150-loop of an influenza A virus group-1 sialidase [PDF]

, 2010
This work was supported by the Medical Research Council and the Scottish Funding Council.Influenza virus sialidase has an essential role in the virus’ life cycle.
Russell, Rupert James Martin, Thomson, Robin J, Thomson, Robin, Dyason, Jeffrey C, von Itzstein, M, Naffakh, Nadia, S. Kerry, Philip, Nadia Naffakh, Mark von Itzstein, Faith J. Rose, Rameix-Welti, Marie-Anne, Robin J. Thomson, Dyason, Jeffrey, Dyason, JC, Rupert J. M. Russell, van der Werf, S, Russell, Rupert J M, Santosh Rudrawar, Rose, Faith J, Russell, Rupert JM, Kerry, Philip Stephen, Jeffrey C. Dyason, von Itzstein, Mark, Thomson, RJ, J.M. Russell, Rupert, Rudrawar, S, Marie-Anne Rameix-Welti, Kerry, Philip S, Rose, FJ, Naffakh, N, Rameix-Welti, MA, Philip S. Kerry, van Der Werf, Sylvie, Rose, Faith, Rudrawar, Santosh, Sylvie van der Werf   +35 more
core   +1 more source

Emergence and spread of novel H5N8, H5N5 and H5N1 clade 2.3.4.4 highly pathogenic avian influenza in 2020

Emerging Microbes and Infections, 2021
Analyses of HPAI H5 viruses from poultry outbreaks across a wide Eurasian region since July 2020 including the Russian Federation, Republics of Iraq and Kazakhstan, and recent detections in migratory waterfowl in the Netherlands, revealed undetected ...
Nicola S. Lewis, Ashley C. Banyard, Elliot Whittard, Talgat Karibayev, Thamer Al Kafagi, Ilya Chvala, Alex Byrne, Saduakassova Meruyert (Akberovna), Jacqueline King, Timm Harder, Christian Grund, Steve Essen, Scott M. Reid, Adam Brouwer, Nikolay G. Zinyakov, Azimkhan Tegzhanov, Victor Irza, Anne Pohlmann, Martin Beer, Ron A. M. Fouchier, Sultanov Akhmetzhan (Akievich), Ian H. Brown   +21 more
doaj   +1 more source

Discordant correlation between serological assays observed when measuring heterosubtypic responses against avian influenza H5 and H7 viruses in unexposed individuals [PDF]

, 2014
The human population is constantly exposed to multiple influenza A subtypes due to zoonotic spill over and rapid viral evolution driven by intrinsic error-prone replication and immunological pressure.
Ferrara, Francesca, Temperton, Nigel J., Temperton, Nigel, Lapini, Giulia, Molesti, Eleonora, Montomoli, Emanuele   +5 more
core   +1 more source

Generation of Nasal Cell‐Derived Human Alveolar Organoids and Organoid‐Macrophage Assembloids for in Vitro Lung Modeling

Advanced Science, EarlyView.
This study demonstrates the generation of human alveolar organoids from nasal cells, which, when co‐cultured with monocyte‐derived macrophages, promotes maturation of both components and forms alveolar assembloids resembling native alveoli. These alveolar organoids and assembloids offer accessible, physiologically relevant in vitro systems for ...
Man Chun Chiu, Shuxin Zhang, Cun Li, Yifei Yu, Zhixin Wan, Jingjing Huang, Wei Xue, Ying Zhou, Xiaoxin Zhu, Qiaoshuai Lan, Jiali Wu, Zijun Zhao, Yuhong Liu, Xinjie Meng, Lin Huang, Hin Chu, Honglin Chen, Kelvin Kai‐Wang To, Kwok Yung Yuen, Jie Zhou   +19 more
wiley   +1 more source

Redesign and Validation of a Real-Time RT-PCR to Improve Surveillance for Avian Influenza Viruses of the H9 Subtype

Viruses, 2022
Avian influenza viruses of the H9 subtype cause significant losses to poultry production in endemic regions of Asia, Africa and the Middle East and pose a risk to human health. The availability of reliable and updated diagnostic tools for H9 surveillance
Valentina Panzarin, Sabrina Marciano, Andrea Fortin, Irene Brian, Valeria D’Amico, Federica Gobbo, Francesco Bonfante, Elisa Palumbo, Yoshihiro Sakoda, Kien Trung Le, Duc-Huy Chu, Ismaila Shittu, Clement Meseko, Abdoul Malick Haido, Theophilus Odoom, Mame Nahé Diouf, Fidélia Djegui, Mieke Steensels, Calogero Terregino, Isabella Monne   +19 more
doaj   +1 more source

Chinese avian influenza

BMJ, 1998
Influenza viruses are unique among respiratory viruses in exhibiting “drift,” which is change in surface antigens as a result of host immunological pressure. In addition, influenza A viruses exhibit “shift”—which is the genetic intermingling of human strains with animal or bird strains, resulting in completely new viruses of pandemic potential.
E, Walker, P, Christie
openaire   +3 more sources