Results 1 to 10 of about 15,800,632 (221)

Differential contribution of PB1-F2 to the virulence of highly pathogenic H5N1 influenza A virus in mammalian and avian species. [PDF]

PLoS Pathogens, 2011
Highly pathogenic avian influenza A viruses (HPAIV) of the H5N1 subtype occasionally transmit from birds to humans and can cause severe systemic infections in both hosts.
Mirco Schmolke, Balaji Manicassamy, Lindomar Pena, Troy Sutton, Rong Hai, Zsuzsanna T Varga, Benjamin G Hale, John Steel, Daniel R Pérez, Adolfo García-Sastre   +9 more
doaj   +3 more sources

PB2 Segment Promotes High-pathogenicity Of H5N1 Avian Influenza Viruses In Mice [PDF]

Frontiers in Microbiology, 2015
H5N1 influenza viruses with high lethality are a continuing threat to humans and poultry. Recently, H5N1 high-pathogenicity avian influenza virus (HPAIV) has been shown to transmit through aerosols between ferrets in lab experiments by acquiring some ...
Hailiang eSun, pengfei ecui, yafen esong, yan eqi, xiaokang eli, wenbao eqi, chenggang exu, Peirong eJiao, ming eliao   +8 more
doaj   +3 more sources

Highly Pathogenic Avian Influenza A(H7N9) Virus, Tennessee, USA, March 2017

Emerging Infectious Diseases, 2017
In March 2017, highly pathogenic avian influenza A(H7N9) was detected at 2 poultry farms in Tennessee, USA. Surveillance data and genetic analyses indicated multiple introductions of low pathogenicity avian influenza virus before mutation to high ...
Dong-Hun Lee, Mia K. Torchetti, Mary Lea Killian, Yohannes Berhane, David E. Swayne   +4 more
doaj   +1 more source

Investigating the Genetic Diversity of H5 Avian Influenza Viruses in the United Kingdom from 2020–2022

Microbiology Spectrum, 2023
Since 2020, the United Kingdom and Europe have experienced annual epizootics of high-pathogenicity avian influenza virus (HPAIV). The first epizootic, during the autumn/winter of 2020–2021, involved six H5Nx subtypes, although H5N8 HPAIV dominated in the
Alexander M. P. Byrne, Joe James, Benjamin C. Mollett, Stephanie M. Meyer, Thomas Lewis, Magdalena Czepiel, Amanda H. Seekings, Sahar Mahmood, Saumya S. Thomas, Craig S. Ross, Dominic J. F. Byrne, Michael J. McMenamy, Valerie Bailie, Ken Lemon, Rowena D. E. Hansen, Marco Falchieri, Nicola S. Lewis, Scott M. Reid, Ian H. Brown, Ashley C. Banyard   +19 more
doaj   +1 more source

A Dutch highly pathogenic H5N6 avian influenza virus showed remarkable tropism for extra-respiratory organs and caused severe disease but was not transmissible via air in the ferret model

mSphere, 2023
Continued circulation of A/H5N1 influenza viruses of the A/goose/Guangdong/1/96 lineage in poultry has resulted in the diversification in multiple genetic and antigenic clades. Since 2009, clade 2.3.4.4 hemagglutinin (HA) containing viruses harboring the
Sander Herfst, Lineke Begeman, Monique I. Spronken, Marjolein J. Poen, Dirk Eggink, Dennis de Meulder, Pascal Lexmond, Theo M. Bestebroer, Marion P. G. Koopmans, Thijs Kuiken, Mathilde Richard, Ron A. M. Fouchier   +11 more
doaj   +1 more source

Genetic and biological characteristics of avian influenza virus subtype H1N8 in environments related to live poultry markets in China

BMC Infectious Diseases, 2019
Background Since 2008, avian influenza surveillance in poultry-related environments has been conducted annually in China. Samples have been collected from environments including live poultry markets, wild bird habitats, slaughterhouses, and poultry farms.
Ye Zhang, Jie Dong, Hong Bo, Libo Dong, Shumei Zou, Xiyan Li, Yuelong Shu, Dayan Wang   +7 more
doaj   +1 more source

Genetic Characterization and Pathogenicity of H7N7 and H7N9 Avian Influenza Viruses Isolated from South Korea

Viruses, 2021
H7 low pathogenic avian influenza viruses (LPAIVs) can mutate into highly pathogenic avian influenza viruses (HPAIVs). In addition to avian species, H7 avian influenza viruses (AIVs) also infect humans.
Eun-Jee Na, Young-Sik Kim, Yoon-Ji Kim, Jun-Soo Park, Jae-Ku Oem   +4 more
doaj   +1 more source

D701N mutation in the PB2 protein contributes to the pathogenicity of H5N1 avian influenza viruses but not transmissibility in guinea pigs

Frontiers in Microbiology, 2014
H5N1 highly pathogenic avian influenza virus (HPAIV) of clade 2.3.2 has been circulating in waterfowl in Southern China since 2003. Our previous studies showed that certain H5N1 HPAIV isolates within clade 2.3.2 from Southern China had high pathogenicity
Peirong eJiao, Liangmeng eWei, Yafen eSong, Jin eCui, Hui eSong, Lan eCao, Runyu eYuan, Kaijian eLuo, Ming eLiao   +8 more
doaj   +1 more source

Analysis of marker substitutions in A/chicken/Astrakhan/2171-1/2020 H5N8 isolate of avian influenza virus recovered in the Astrakhan Oblast

Ветеринария сегодня, 2021
At the end of 2020, a large-scale bird death was registered at one of the poultry farms in the Astrakhan region, the cause of which was avian influenza.
N. G. Zinyakov, A. V. Andriyasov, Ye. V. Ovchinnikova, A. A. Kozlov, P. D. Zhestkov, D. B. Andreychuk, I. A. Chvala   +6 more
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Genetic Characterization and Zoonotic Potential of Highly Pathogenic Avian Influenza Virus A(H5N6/H5N5), Germany, 2017–2018

Emerging Infectious Diseases, 2019
We genetically characterized highly pathogenic avian influenza virus A(H5N6) clade 2.3.4.4b isolates found in Germany in 2017–2018 and assessed pathogenicity of representative H5N5 and H5N6 viruses in ferrets. These viruses had low pathogenicity; however,
Anne Pohlmann, Donata Hoffmann, Christian Grund, Susanne Koethe, Daniela Hüssy, Simone M. Meier, Jacqueline King, Jan Schinköthe, Reiner Ulrich, Timm Harder, Martin Beer   +10 more
doaj   +1 more source