Results 1 to 10 of about 13,429 (224)

The Protective Effects of the A/ZJU01/ PR8/2013 Split H7N9 Avian Influenza Vaccine Against Highly Pathogenic H7N9 in BALB/c Mice

Cellular Physiology and Biochemistry, 2018
Background/Aims: Since the first case of novel H7N9 infection was reported, China has experienced five epidemics of H7N9. During the fifth wave, a highly pathogenic H7N9 strain emerged. In order to assess whether the H7N9 vaccine based on A/Zhejiang/DTID-
Xiao-Xin Wu, Xi-Long Deng, Dong-Shan Yu, Wei Yao, Hui-Lin Ou, Tian-Hao Weng, Chen-Yu Hu, Feng-Yu Hu, Nan-Ping Wu, Hangping Yao, Fu-Chun Zhang, Lan-Juan Li   +11 more
doaj   +3 more sources

Genetic and biological properties of H7N9 avian influenza viruses detected after application of the H7N9 poultry vaccine in China

PLoS Pathogens, 2021
The H7N9 avian influenza virus (AIV) that emerged in China have caused five waves of human infection. Further human cases have been successfully prevented since September 2017 through the use of an H7N9 vaccine in poultry.
Yulei Li, Chengjun Li, Hualan Chen
exaly   +2 more sources

H7N9 Influenza Virus Containing a Polybasic HA Cleavage Site Requires Minimal Host Adaptation to Obtain a Highly Pathogenic Disease Phenotype in Mice

Viruses, 2020
Low pathogenic avian influenza (LPAI) H7N9 viruses have recently evolved to gain a polybasic cleavage site in the hemagglutinin (HA) protein, resulting in variants with increased lethality in poultry that meet the criteria for highly pathogenic avian ...
Mable Chan, Anders Leung, Tamiko Hisanaga, Brad Pickering, Bryan D. Griffin, Robert Vendramelli, Nikesh Tailor, Gary Wong, Yuhai Bi, Shawn Babiuk, Yohannes Berhane, Darwyn Kobasa   +11 more
doaj   +1 more source

Surveillance of Avian H7N9 Virus in Various Environments of Zhejiang Province, China before and after Live Poultry Markets Were Closed in 2013-2014. [PDF]

PLoS ONE, 2015
To date, there have been a total of 637 laboratory-confirmed cases of human infection with avian influenza A (H7N9) virus across mainland China, with 28% (179/637) of these reported in Zhejiang Province.
Xiaoxiao Wang, Shelan Liu, Haiyan Mao, Zhao Yu, Enfu Chen, Chengliang Chai   +5 more
doaj   +1 more source

Development of rapid immunochromatographic test for hemagglutinin antigen of H7 subtype in patients infected with novel avian influenza A (H7N9) virus. [PDF]

PLoS ONE, 2014
BACKGROUND: Since human infection with the novel H7N9 avian influenza virus was identified in China in March 2013, the relatively high mortality rate and possibility of human-to-human transmission have highlighted the urgent need for sensitive and ...
Keren Kang, Li Chen, Xiang Zhao, Chengfeng Qin, Zanwu Zhan, Jihua Wang, Wenmei Li, Emmanuel E Dzakah, Weijuang Huang, Yuelong Shu, Tao Jiang, Wuchun Cao, Mingquan Xie, Xiaochun Luo, Shixing Tang   +14 more
doaj   +1 more source

Identifying novel amino acid substitutions of hemagglutinin involved in virulence enhancement in H7N9 virus strains

Virology Journal, 2021
Background To identify site-specific features of amino acid substitutions that confer enhanced H7N9 virulence in humans, we independently generated mammalian-adapted variants of A/Anhui/1/2013 (AH-H7N9) and A/Shanghai/2/2013 (SH-H7N9) by serial passaging
Ting Zhang, Haiwei Du, Li Guo, Feng Liu, Haoxiang Su, Fan Yang   +5 more
doaj   +1 more source

Hemagglutinin-Specific Non-neutralizing Antibody Is Essential for Protection Provided by Inactivated and Viral-Vectored H7N9 Avian Influenza Vaccines in Chickens

Frontiers in Veterinary Science, 2020
Hemagglutination inhibition (HI) and virus neutralization antibody (nAb) do not always correlate with the protection of H7 avian influenza vaccines in mammals and humans.
Zenglei Hu, Zenglei Hu, Zenglei Hu, Zenglei Hu, Jiangyan Zhao, Yiheng Zhao, Xuelian Fan, Jiao Hu, Jiao Hu, Lei Shi, Xiaoquan Wang, Xiaoquan Wang, Xiaowen Liu, Xiaowen Liu, Shunlin Hu, Shunlin Hu, Min Gu, Min Gu, Yongzhong Cao, Yongzhong Cao, Yongzhong Cao, Xiufan Liu, Xiufan Liu, Xiufan Liu, Xiufan Liu   +24 more
doaj   +1 more source

Supplementation of H7N9 Virus-Like Particle Vaccine With Recombinant Epitope Antigen Confers Full Protection Against Antigenically Divergent H7N9 Virus in Chickens

Frontiers in Immunology, 2022
The continuous evolution of the H7N9 avian influenza virus suggests a potential outbreak of an H7N9 pandemic. Therefore, to prevent a potential epidemic of the H7N9 influenza virus, it is necessary to develop an effective crossprotective influenza ...
Dexin Kong, Dexin Kong, Dexin Kong, Dexin Kong, Taoran Chen, Taoran Chen, Taoran Chen, Taoran Chen, Xiaolong Hu, Xiaolong Hu, Xiaolong Hu, Xiaolong Hu, Shaorong Lin, Shaorong Lin, Shaorong Lin, Shaorong Lin, Yinze Gao, Yinze Gao, Yinze Gao, Yinze Gao, Chunmei Ju, Ming Liao, Ming Liao, Ming Liao, Ming Liao, Huiying Fan, Huiying Fan, Huiying Fan, Huiying Fan   +28 more
doaj   +1 more source

Comparison of acute respiratory distress syndrome in patients with COVID-19 and influenza A (H7N9) virus infection

International Journal of Infectious Diseases, 2022
Objectives: We aimed to compared the clinical features of acute respiratory distress syndrome (ARDS) induced by COVID-19 and H7N9 virus infections.
Ling Ding, Yikun Chen, Nan Su, Xizhen Xu, Jingping Yin, Jun Qiu, Jiajia Wang, Dong Zheng   +7 more
doaj   +1 more source

Mutations in Hemagglutinin of a Novel Avian-Origin H7N9 Virus That Are Critical for Receptor Binding Specificity

Tsinghua Science and Technology, 2013
A novel avian-origin H7N9 influenza virus was discovered in March in China and has caused a total of 131 people infected including 39 deaths in China as of June 9, 2013.
Wei Hu
doaj   +1 more source