Results 21 to 30 of about 13,429 (224)

H7N9 Influenza Virus in China [PDF]

Cold Spring Harbor Perspectives in Medicine, 2020
In early 2013, human infections caused by a novel H7N9 avian influenza virus (AIV) were first reported in China; these infections caused severe disease and death. The virus was initially low pathogenic to poultry, enabling it to spread widely in different provinces, especially in live poultry markets.
Chengjun, Li, Hualan, Chen
openaire   +2 more sources

Extra Oversight for H7N9 Experiments [PDF]

Science, 2013
The U.S. Department of Health and Human Services (HHS) announces a new review process for certain gain-of-function (GOF) experiments with the avian influenza A (H7N9) virus, some of which are proposed this week by influenza scientists. Specifically, before being undertaken using funds from the HHS, proposed studies that are reasonably anticipated to ...
Harold, Jaffe, Amy P, Patterson, Nicole, Lurie   +2 more
openaire   +2 more sources

Gain-of-Function Experiments on H7N9 [PDF]

Science, 2013
Since the end of March 2013, avian influenza A viruses of the H7N9 subtype have caused more than 130 human cases of infection in China, many of which were severe, resulting in 43 fatalities. Although this A(H7N9) outbreak is now under control, the virus (or one with similar properties) could re-emerge as winter approaches.To better assess the pandemic ...
Guan, Y, Peiris, JSM, Steel, J, Tompkins, SM, Topham, DJ, Treanor, JJ, Tripp, RA, Webby, RJ, Webster, RG, Smith, DJ, Compans, RW, García-Sastre, A, Govorkova, EA, Herfst, S, Orenstein, WA, Perez, DR, Richt, JA, Russell, C, Schultz-Cherry, SL, Cardona, C, Fouchier, RA, Kawaoka, Y   +21 more
openaire   +7 more sources

Human to human transmission of H7N9 [PDF]

BMJ, 2013
Since the new avian influenza virus, H7N9, first emerged in China, a primary concern has been whether it might spread between humans. The vast majority of the 133 confirmed cases reported so far seem to be epidemiologically unconnected, with many patients reporting a recent history of exposure to live poultry, which are suspected to be a main reservoir
Rudge, James W, Coker, Richard
openaire   +2 more sources

Influenza A (H7N9) and the Importance of Digital Epidemiology [PDF]

New England Journal of Medicine, 2013
In recent outbreaks including that of novel H7N9 influenza, digital disease surveillance has supplemented laboratory studies and work by public health officials and epidemiologists, by leveraging widespread use of the Internet, mobile phones, and social media.
Salathé, Marcel, Freifeld, Clark C, Mekaru, Sumiko R, Tomasulo, Anna F, Brownstein, John S   +4 more
openaire   +3 more sources

From H5N1 to HxNy: An epidemiologic overview of human infections with avian influenza in the Western Pacific Region, 2003–2017

Western Pacific Surveillance and Response, 2019
Since the first confirmed human infection with avian influenza A(H5N1) virus was reported in Hong Kong SAR (China) in 1997, sporadic zoonotic avian influenza viruses causing human illness have been identified globally with the World Health Organization ...
Sarah Hamid, Yuzo Arima, Erica Dueger, Frank Konings, Leila Bell, Chin-Kei Lee, Dapeng Luo, Satoko Otsu, Babatunde Olowokure, Ailan Li, WPRO Health Emergencies Programme Team   +10 more
doaj   +1 more source

Novel H7N9 influenza immunogen design enhances mobilization of seasonal influenza T cell memory in H3N2 pre-immune mice

Human Vaccines & Immunotherapeutics, 2022
Strategies that improve influenza vaccine immunogenicity are critical for the development of vaccines for pandemic preparedness. Hemagglutinin (HA)-specific CD4+ T cell epitopes support protective B cell responses against seasonal influenza.
Leonard Moise, Lauren M. Meyers, Hyesun Jang, Mayara Grizotte-Lake, Christine M. Boyle, Bethany McGonnigal, Pan Ge, Ted M. Ross, Anne S. De Groot   +8 more
doaj   +1 more source

Comparative Pathogenicity and Transmissibility of the H7N9 Highly Pathogenic Avian Influenza Virus and the H7N9 Low Pathogenic Avian Influenza Virus in Chickens

Viruses, 2019
There were five outbreaks of H7N9 influenza virus in humans in China since it emerged in 2013, infecting >1000 people. The H7N9 low pathogenic influenza virus was inserted into four amino acids in the HA protein cleavage site to mutate into the H7N9 ...
Hao Yu, Kunpeng Zhang, Xumeng Ye, Wenqing Wang, Wenbo Wu, Xia Wang, Yun Guan, Zhuoliang He, Yong Wang, Peirong Jiao   +9 more
doaj   +1 more source

T cell epitope engineering: an avian H7N9 influenza vaccine strategy for pandemic preparedness and response

Human Vaccines & Immunotherapeutics, 2018
The delayed availability of vaccine during the 2009 H1N1 influenza pandemic created a sense of urgency to better prepare for the next influenza pandemic.
Leonard Moise, Bethany M. Biron, Christine M. Boyle, Nese Kurt Yilmaz, Hyesun Jang, Celia Schiffer, Ted M. Ross, William D. Martin, Anne S. De Groot   +8 more
doaj   +1 more source

Prediction of H7N9 epidemic in China

Chinese Medical Journal, 2014
Background In March 2013, human cases of infection with a novel A (H7N9) influenza virus emerged in China. The epidemic spread quickly and as of 6 May 2013, there were 129 confirmed cases. The purpose of this study was to analyze the epidemiology of the confirmed cases, determine the impacts of bird migration and temperature ...
Zhaojie, Zhang, Yao, Xia, Yi, Lu, Jingchao, Yang, Luwen, Zhang, Hui, Su, Lili, Lin, Guoling, Wang, Tongmei, Wang, Shao, Lin, Zhongmin, Guo, Jiahai, Lu   +11 more
openaire   +2 more sources