Results 1 to 10 of about 4,290,191 (312)

Resource-efficient internally controlled in-house real-time PCR detection of SARS-CoV-2

Virology Journal, 2021
Background The reliable detection of SARS-CoV-2 has become one of the most important contributions to COVID-19 crisis management. With the publication of the first sequences of SARS-CoV-2, several diagnostic PCR assays have been developed and published ...
Janine Michel, Markus Neumann, Eva Krause, Thomas Rinner, Therese Muzeniek, Marica Grossegesse, Georg Hille, Franziska Schwarz, Andreas Puyskens, Sophie Förster, Barbara Biere, Daniel Bourquain, Cristina Domingo, Annika Brinkmann, Lars Schaade, Livia Schrick, Andreas Nitsche   +16 more
doaj   +1 more source

Analysis of Sporulation in Bacillus cereus Biovar anthracis Which Contains an Insertion in the Gene for the Sporulation Factor σ^K

Pathogens, 2023
Bacillus cereus biovar anthracis (Bcbva) is an untypical pathogen causing a fatal anthrax-like disease in a variety of wildlife species in African rainforest areas. In contrast to Bacillus anthracis and most species of the B. cereus group, all strains of
Constanze Gummelt, Susann Dupke, Sabine Howaldt, Fee Zimmermann, Holger C. Scholz, Michael Laue, Silke R. Klee   +6 more
doaj   +1 more source

Francisella tularensis subsp. holarctica wild-type is able to colonize natural aquatic ex vivo biofilms

Frontiers in Microbiology, 2023
Biofilms are a matrix-associated lifestyle of microbial communities, often enabling survivability and persistence of such bacteria. The objective of this study was to investigate the survival of the wild-type strain A-271 of Francisella tularensis subsp.
Christoph Schaudinn, Kerstin Rydzewski, Kerstin Rydzewski, Beate Meister, Roland Grunow, Klaus Heuner, Klaus Heuner   +6 more
doaj   +1 more source

A global dataset of sequence, diversity and biosafety recommendation of arbovirus and arthropod-specific virus

Scientific Data, 2023
Arthropod-borne virus (arbovirus) and arthropod-specific virus (ASV) are viruses circulating amongst hematophagous arthropods that are broadly transmitted in ecological systems.
Ying Huang, Shunlong Wang, Hong Liu, Evans Atoni, Fei Wang, Wei Chen, Zhaolin Li, Sergio Rodriguez, Zhiming Yuan, Zhaoyan Ming, Han Xia   +10 more
doaj   +1 more source

Virulence and resistance patterns of Vibrio cholerae non-O1/non-O139 acquired in Germany and other European countries

Frontiers in Microbiology, 2023
Global warming has caused an increase in the emergence of Vibrio species in marine and estuarine environments as well as fresh water bodies. Over the past decades, antimicrobial resistance (AMR) has evolved among Vibrio species toward various antibiotics
Katarzyna Schmidt, Katarzyna Schmidt, Holger C. Scholz, Sandra Appelt, Jana Michel, Daniela Jacob, Susann Dupke   +6 more
doaj   +1 more source

Phenotypic and genotypic discrimination of Francisella tularensis ssp. holarctica clades

International Journal of Medical Microbiology, 2023
Francisella tularensis is the causative agent of tularemia, a zoonotic disease with a wide host range. F. tularensis ssp. holarctica (Fth) is of clinical relevance for European countries, including Germany.
Kristin Köppen, Kerstin Rydzewski, Joerg Doellinger, Kerstin Myrtennäs, Mats Forsman, Sandra Appelt, Holger Scholz, Klaus Heuner   +7 more
doaj   +1 more source

Differential Efficacy of Novel Antiviral Substances in 3D and Monolayer Cell Culture

Viruses, 2020
Repurposing of approved drugs that target host functions also important for virus replication promises to overcome the shortage of antiviral therapeutics.
Robert Koban, Markus Neumann, Philipp P. Nelson, Heinz Ellerbrok   +3 more
doaj   +1 more source

Ulceroglandular form of tularemia after squirrel bite: a case report

Journal of Medical Case Reports, 2022
Background The diagnosis of tularemia is not often considered in Germany as the disease is still rare in this country. Nonetheless, Francisella tularensis, the causative agent of tularemia, can infect numerous animal species and should, therefore, not be
Hannah Sophia Borgschulte, Daniela Jacob, Jörg Zeeh, Holger C. Scholz, Klaus Heuner   +4 more
doaj   +1 more source

Seasonal and inter-annual variation of malaria parasite detection in wild chimpanzees

Malaria Journal, 2018
Background Cross-sectional surveys of chimpanzee (Pan troglodytes) communities across sub-Saharan Africa show large geographical variation in malaria parasite (Plasmodium spp.) prevalence.
Doris F. Wu, Therese Löhrich, Andreas Sachse, Roger Mundry, Roman M. Wittig, Sébastien Calvignac-Spencer, Tobias Deschner, Fabian H. Leendertz   +7 more
doaj   +1 more source

A novel Coltivirus-related virus isolated from free-tailed bats from Côte d’Ivoire is able to infect human cells in vitro

Virology Journal, 2017
Background Zoonotic transmission events play a major role in the emergence of novel diseases. While such events are virtually impossible to predict, wildlife screening for potential emerging pathogens can be a first step.
Sabrina Weiss, Piotr Wojtek Dabrowski, Andreas Kurth, Siv Aina J. Leendertz, Fabian H. Leendertz   +4 more
doaj   +1 more source