Results 1 to 10 of about 25,700 (224)

Longitudinal Surveillance of Influenza A Virus Exposure in Wild Boars (Sus scrofa) in Spain (2015-2023): Serologic and Virologic Evidence of Subtype Infections and H5N1 Spillover Risk. [PDF]

Zoonoses Public Health
ABSTRACT Introduction Influenza A viruses (IAVs) are responsible for respiratory infections in a wide range of species, including birds, swine and humans. The role of wild boar (Sus scrofa) in IAV epidemiology remains underexplored. Here, we present a longitudinal serologic and virologic surveillance study of wild boars in Spain from 2015 to 2023 ...
Encinas P, Nogales A, Escribano-Romero E, Del Burgo MÁM, López-Olvera JR, Granados JE, Mentaberre G, García-Sastre A, Del Real G.   +8 more
europepmc   +2 more sources

Influenza A Virus H5N1 Subtype: Resurgent Interspecies and Intercontinental Transmission, and a New Host [PDF]

Pathogens
It has been more than 25 years since the avian influenza A virus (IAV) H5N1 subtype emerged in humans in 1997. Since then, this virus has become endemic in poultry and wild birds and has been causing sporadic infections in humans.
Matloob Husain
doaj   +2 more sources

Avian influenza overview December 2025–February 2026 [PDF]

EFSA J
Abstract Between 29 November 2025 and 27 February 2026, 2514 highly pathogenic avian influenza (HPAI) A(H5) virus detections were reported in domestic (406) and wild (2108) birds in 32 countries in Europe. Albeit still at high levels after the peak was reached at the beginning of the current reporting period, the weekly number of detections has since ...
European Food Safety Authority (EFSA), European Centre for Disease Prevention and Control (ECDC), European Union Reference Laboratory for Avian Influenza (EURL), Cyril Barbezange, Hubert Buczkowski, Mariette Ducatez, Alice Fusaro, Jose L. Gonzales, Thijs Kuiken, Gražina Mirinavičiūtė, Karl Ståhl, Christoph Staubach, Olov Svartström, Calogero Terregino, Katriina Willgert, Evelyn Alarcón, Lisa Kohnle   +16 more
europepmc   +2 more sources

Evolution of H5N1 Cross-Species Transmission: Adaptive Mutations Driving Avian-to-Human Infection. [PDF]

Adv Genet (Hoboken)
This review synthesizes current knowledge on the molecular mechanisms underpinning H5N1's host adaptation, focusing on key mutations in viral proteins. Critical mutations are discussed in detail, highlighting their roles in altering receptor specificity, promoting antiviral resistance, and expanding viral tropism. The review underscores the urgent need
Man W, Du L, Liu Y, Pang Z, Zhu H, Hong B, Xu Z, Fan H.   +7 more
europepmc   +2 more sources

Insight into highly conserved H1 subtype-specific epitopes in influenza virus hemagglutinin [PDF]

, 2014
Influenza viruses continuously undergo antigenic changes with gradual accumulation of mutations in hemagglutinin (HA) that is a major determinant in subtype specificity.
Cho, Ki Joon, Hong, Kwang W, Kim, Kyung Hyun, Kim, Se-Ho, Kim, Sella, Lee, Ji-Hye, Saelens, Xavier, Seok, Jong Hyeon   +7 more
core   +17 more sources

Avian Influenza Virus A Subtype H5N1

UMI Medical Journal, 2023
Latar Belakang: Avian influenza adalah infeksi virus menular yang menyerang unggas, hewan, dan manusia di seluruh dunia. Sebagian besar infeksi pada manusia disebabkan oleh virus influenza tipe A dan B, sedangkan unggas hanya terinfeksi oleh influenza tipe A. Isi: Masa inkubasi umumnya 2 sampai 7 hari, tapi bisa selama 8 sampai 9 hari.
Erza Anugrah, M. Almutaali
openaire   +1 more source

Determinants of Antiviral Effectiveness in Influenza Virus A Subtype H5N1 [PDF]

Journal of Infectious Diseases, 2012
Oseltamivir is widely used as treatment for influenza virus A subtype H5N1 (hereafter, "H5N1") infection but, like any intervention, is not always effective.We used Avian Influenza Registry data from 10 countries to examine the risk of death in 215 patients with confirmed H5N1 infection who were treated with oseltamivir, according to viral clade, age ...
Dreyer, Nancy A., Zaman, Mukhtiar, Hanshaoworakul, Wanna, Chan, Paul K. S., Gasimov, Viktor, Toovey, Stephen, Lee, Nelson, Oner, Ahmet Faik, Tsang, Owen, Phommasack, Bounlay, Coker, Richard, Adisasmito, Wiku, Touch, Sok, Bamgboye, Ebun, Swenson, Anna, DOĞAN, Nazim   +15 more
openaire   +4 more sources

Generation and characterisation of monoclonal antibodies against influenza virus A, subtype H5N1 [PDF]

Journal of Virological Methods, 2011
The emergence of highly pathogenic avian influenza A virus (HPAIV) subtype H5N1 in 1997 has since resulted in large outbreaks in poultry and in transmission from poultry to humans, mostly in southeast Asia, but also in several European countries. Effective diagnosis and control measures are essential for the management of HPAIV infections. To develop a
Linke, Sonja, Neubauer, Katrin, Dorner, Martin, Dorner, Brigitte, Pauli, Georg, Schweiger, Brunhilde   +5 more
openaire   +3 more sources

Serological survey for avian influenza virus infection of backyard poultry and poultry workers in Baghdad and Basrah provinces, Iraq [PDF]

Bulgarian Journal of Veterinary Medicine, 2020
The aim of this study was to determine the prevalence of avian influenza virus (AIV) subtype H5N1 among backyard birds and poultry workers. The study included backyard birds (chickens and ducks) in rural areas of Baghdad and Basrah provinces, Iraq. Rural
S. Jaber, H. T. Thwiny
doaj   +1 more source

A recombinant vaccine of H5N1 HA1 fused with foldon and human IgG Fc induced complete cross-clade protection against divergent H5N1 viruses. [PDF]

PLoS ONE, 2011
Development of effective vaccines to prevent influenza, particularly highly pathogenic avian influenza (HPAI) caused by influenza A virus (IAV) subtype H5N1, is a challenging goal.
Lanying Du, Virtual Ho-Chuen Leung, Xiujuan Zhang, Jie Zhou, Min Chen, Wu He, Hai-Ying Zhang, Chris C S Chan, Vincent Kwok-Man Poon, Guangyu Zhao, Shihui Sun, Lifeng Cai, Yusen Zhou, Bo-Jian Zheng, Shibo Jiang   +14 more
doaj   +1 more source