Results 11 to 20 of about 20,121 (221)

Llama-derived single domain antibodies to build multivalent, superpotent and broadened neutralizing anti-viral molecules. [PDF]

PLoS ONE, 2011
For efficient prevention of viral infections and cross protection, simultaneous targeting of multiple viral epitopes is a powerful strategy. Llama heavy chain antibody fragments (VHH) against the trimeric envelope proteins of Respiratory Syncytial Virus (
Anna Hultberg, Nigel J Temperton, Valérie Rosseels, Mireille Koenders, Maria Gonzalez-Pajuelo, Bert Schepens, Lorena Itatí Ibañez, Peter Vanlandschoot, Joris Schillemans, Michael Saunders, Robin A Weiss, Xavier Saelens, José A Melero, C Theo Verrips, Steven Van Gucht, Hans J de Haard   +15 more
doaj   +2 more sources

Influenza H5N1 virus infection of polarized human alveolar epithelial cells and lung microvascular endothelial cells [PDF]

Respiratory Research, 2009
Background Highly pathogenic avian influenza (HPAI) H5N1 virus is entrenched in poultry in Asia and Africa and continues to infect humans zoonotically causing acute respiratory disease syndrome and death.
Yuen Kit M, Lo CK, Chui WH, Ho Carol CC, Yu Wendy CL, Chan Renee WY, Chan Michael CW, Guan Yi, Nicholls John M, Peiris JS Malik   +9 more
doaj   +2 more sources

Generation and characterisation of monoclonal antibodies against influenza virus A, subtype H5N1 [PDF]

Journal of Virological Methods, 2011
The emergence of highly pathogenic avian influenza A virus (HPAIV) subtype H5N1 in 1997 has since resulted in large outbreaks in poultry and in transmission from poultry to humans, mostly in southeast Asia, but also in several European countries. Effective diagnosis and control measures are essential for the management of HPAIV infections. To develop a
Linke, Sonja, Neubauer, Katrin, Dorner, Martin, Dorner, Brigitte, Pauli, Georg, Schweiger, Brunhilde   +5 more
openaire   +3 more sources

A recombinant vaccine of H5N1 HA1 fused with foldon and human IgG Fc induced complete cross-clade protection against divergent H5N1 viruses. [PDF]

PLoS ONE, 2011
Development of effective vaccines to prevent influenza, particularly highly pathogenic avian influenza (HPAI) caused by influenza A virus (IAV) subtype H5N1, is a challenging goal.
Lanying Du, Virtual Ho-Chuen Leung, Xiujuan Zhang, Jie Zhou, Min Chen, Wu He, Hai-Ying Zhang, Chris C S Chan, Vincent Kwok-Man Poon, Guangyu Zhao, Shihui Sun, Lifeng Cai, Yusen Zhou, Bo-Jian Zheng, Shibo Jiang   +14 more
doaj   +1 more source

H5Nx Viruses Emerged during the Suppression of H5N1 Virus Populations in Poultry

Microbiology Spectrum, 2021
Highly pathogenic avian influenza (HPAI) H5 viruses have posed a substantial pandemic threat through repeated human infection since their emergence in China in 1996. Nationwide control measures, including vaccination of poultry, were implemented in 2005,
Yao-Tsun Li, Yvonne C. F. Su, Gavin J. D. Smith   +2 more
doaj   +1 more source

A study of analysis PB1-F2 protein of Influenza Viruses A/H1N1pdm09, A/ H3N2, and A/H5N1

Health Science Journal of Indonesia, 2016
Abstrak Tujuan. Protein PB1-F2 (polymerase basic 1-frame 2) adalah protein terbaru yang ditemukan pada virus Influenza dan telah terbukti berperan dalam induksi kematian sel dan patogenitas. Tujuan dari tulisan ini adalah untuk menganalisis protein PB1-
Hana Apsari Pawestri, I Gusti Ngurah Kade Mahardika   +1 more
doaj   +3 more sources

Latex Agglutination Test for Monitoring Antibodies to Avian Influenza Virus Subtype H5N1 [PDF]

Journal of Clinical Microbiology, 2005
ABSTRACT A latex agglutination test (LAT) based on polystyrene beads sensitized with inactivated avian influenza virus H5N1 particles was developed. Compared with the hemagglutination inhibition test, the sensitivity and specificity of the LAT were 88.8 and 97.6%, respectively, in detecting 830 serum samples from vaccinated chickens. The test
Xiaojuan, Xu, Meilin, Jin, Zhengjun, Yu, Hongchao, Li, Dexin, Qiu, Yadi, Tan, Huanchun, Chen   +6 more
openaire   +2 more sources

Deteksi, Isolasi, dan Identifikasi Avian influenza Subtipe H5N1 pada Unggas di Pulau Jawa, Indonesia Tahun 2016 (DETECTION, ISOLATION AND IDENTIFICATION OF H5N1 SUBTYPE AVIAN INFLUENZA IN POULTRY IN JAVA ISLAND, INDONESIA, 2016)

Jurnal Veteriner, 2018
H5N1 subtype Avian influenza has harmed for poultry in Indonesia currently. Since clade 2.3.2 Avian influenza has been found in waterfowl from 2012, mortality of waterfowl has been occured until now. Change of extreme weather condition with high rainfall
Dyah Ayu Hewajuli, Ni Luh Putu Indi Dharmayanti, I Wayan Teguh Wibawan   +2 more
doaj   +1 more source

Cross-subtype Immunity against Avian Influenza in Persons Recently Vaccinated for Influenza

Emerging Infectious Diseases, 2008
Avian influenza virus (H5N1) can be transmitted to humans, resulting in a severe or fatal disease. The aim of this study was to evaluate the immune cross-reactivity between human and avian influenza (H5N1) strains in healthy donors vaccinated for ...
Cristiana Gioia, Concetta Castilletti, Massimo Tempestilli, Paola Piacentini, Licia Bordi, Roberta Chiappini, Chiara Agrati, Salvatore Squarcione, Giuseppe Ippolito, Vincenzo Puro, Maria Rosaria Capobianchi, Fabrizio Poccia   +11 more
doaj   +1 more source

Differential contribution of PB1-F2 to the virulence of highly pathogenic H5N1 influenza A virus in mammalian and avian species [PDF]

, 2011
Highly pathogenic avian influenza A viruses (HPAIV) of the H5N1 subtype occasionally transmit from birds to humans and can cause severe systemic infections in both hosts.
García-Sastre, Adolfo, García-Sastre, A., Rong Hai, Hale Benjamin G., Pena, Lindomar, Hai, Rong, John Steel, Manicassamy Balaji, Daniel R. Pérez, Pérez Daniel R., Manicassamy, Balaji, Pena, L., Benjamin G. Hale, Sutton, T., Zsuzsanna T Varga, Troy Sutton, Sutton Troy, Varga Zsuzsanna T., Hale, B.G., Varga, Zsuzsanna T, Pena Lindomar, Zsuzsanna T. Varga, Hale, Benjamin G, Balaji Manicassamy, Adolfo García-Sastre, Schmolke, M., Hai Rong, Hai, R., Daniel R Pérez, Pérez, D.R., Sutton, Troy, Steel, John, Pérez, Daniel R, Steel, J., Steel John, García-Sastre Adolfo, Manicassamy, B., Mirco Schmolke, Lindomar Pena, Benjamin G Hale, Schmolke, Mirco, Varga, Z.T., Schmolke Mirco   +42 more
core   +1 more source