Results 11 to 20 of about 114,208,328 (217)

Llama-derived single domain antibodies to build multivalent, superpotent and broadened neutralizing anti-viral molecules. [PDF]

PLoS ONE, 2011
For efficient prevention of viral infections and cross protection, simultaneous targeting of multiple viral epitopes is a powerful strategy. Llama heavy chain antibody fragments (VHH) against the trimeric envelope proteins of Respiratory Syncytial Virus (
Anna Hultberg, Nigel J Temperton, Valérie Rosseels, Mireille Koenders, Maria Gonzalez-Pajuelo, Bert Schepens, Lorena Itatí Ibañez, Peter Vanlandschoot, Joris Schillemans, Michael Saunders, Robin A Weiss, Xavier Saelens, José A Melero, C Theo Verrips, Steven Van Gucht, Hans J de Haard   +15 more
doaj   +2 more sources

H5N1 Clade 2.3.4.4b Infections in Domestic Cats During an Avian Influenza Outbreak in Italy: Implications for One Health Surveillance. [PDF]

Influenza Other Respir Viruses
ABSTRACT Background H5Nx goose/Guangdong (Gs/GD) lineage highly pathogenic avian influenza (HPAI) viruses pose a significant public health threat due to their global spread, mutation accumulation, and expanding host range. The descendant clade 2.3.4.4b has been causing widespread infections in birds and increasing spillover events in mammals.
D'Annunzio G, Moreno A, Tosi G, Bassi P, Bortolami A, Diegoli G, Drago A, Fusaro A, Gelmini L, Gibelli LR, Lazzarotto T, Lilliu E, Piccolomini LL, Maroni A, Martini E, Matteo G, Mattei G, Muscatello LV, Monne I, Palumbo E, Prezzemolo G, Ravaioli V, Resi D, Ruocco L, Sabatino MO, Savegnago E, Sordilli M, Terregino C, Tolini C, Merialdi G.   +29 more
europepmc   +2 more sources

CD4⁺ T-cell responses directed towards A/H5N1-derived haemagglutinin peptides increase in patients with seasonal influenza A virus infection. [PDF]

Clin Transl Immunology
Abstract Objectives Recent outbreak of influenza A/H5N1 viral infections in birds and mammals worldwide prompted renewed concerns over an emerging H5N1‐related influenza pandemic in the generally immunologically‐naive global population. Cross‐reactive CD4+ T cells between A/H1N1 and A/H5N1 subtypes targeting internal and surface influenza proteins have
Allen LF, Rowntree LC, Jenzen M, Hagen RR, Croft NP, James F, Martin GE, Purcell AW, Illing PT, Tong SYC, Cheng AC, Kotsimbos TC, Trubiano JA, Kedzierska K, Nguyen THO.   +14 more
europepmc   +2 more sources

Serological Surveillance of Avian Influenza Virus Exposure Using Paired Sera Among Occupational Contacts in Taiwan, January-September 2025. [PDF]

Influenza Other Respir Viruses
ABSTRACT In 2025, Taiwan implemented paired sera surveillance among occupational contacts of avian influenza viruses (AIVs). Of 122 contacts analyzed, 117 (95.9%) remained asymptomatic with high personal protective equipment compliance (91.8%). No seroconversion was detected against AIV A(H5N2) clade 2.3.4.4b. These findings suggest a low risk of human
Lin CY, Tsou TP, Chu PW, Yang SE, Yu IL, Li YT, Liu MT, Chih YC.   +7 more
europepmc   +2 more sources

A study of analysis PB1-F2 protein of Influenza Viruses A/H1N1pdm09, A/ H3N2, and A/H5N1

Health Science Journal of Indonesia, 2016
Abstrak Tujuan. Protein PB1-F2 (polymerase basic 1-frame 2) adalah protein terbaru yang ditemukan pada virus Influenza dan telah terbukti berperan dalam induksi kematian sel dan patogenitas. Tujuan dari tulisan ini adalah untuk menganalisis protein PB1-
Hana Apsari Pawestri, I Gusti Ngurah Kade Mahardika   +1 more
doaj   +3 more sources

Latex Agglutination Test for Monitoring Antibodies to Avian Influenza Virus Subtype H5N1 [PDF]

Journal of Clinical Microbiology, 2005
ABSTRACT A latex agglutination test (LAT) based on polystyrene beads sensitized with inactivated avian influenza virus H5N1 particles was developed. Compared with the hemagglutination inhibition test, the sensitivity and specificity of the LAT were 88.8 and 97.6%, respectively, in detecting 830 serum samples from vaccinated chickens. The test
Xiaojuan, Xu, Meilin, Jin, Zhengjun, Yu, Hongchao, Li, Dexin, Qiu, Yadi, Tan, Huanchun, Chen   +6 more
openaire   +2 more sources

Deteksi, Isolasi, dan Identifikasi Avian influenza Subtipe H5N1 pada Unggas di Pulau Jawa, Indonesia Tahun 2016 (DETECTION, ISOLATION AND IDENTIFICATION OF H5N1 SUBTYPE AVIAN INFLUENZA IN POULTRY IN JAVA ISLAND, INDONESIA, 2016)

Jurnal Veteriner, 2018
H5N1 subtype Avian influenza has harmed for poultry in Indonesia currently. Since clade 2.3.2 Avian influenza has been found in waterfowl from 2012, mortality of waterfowl has been occured until now. Change of extreme weather condition with high rainfall
Dyah Ayu Hewajuli, Ni Luh Putu Indi Dharmayanti, I Wayan Teguh Wibawan   +2 more
doaj   +1 more source

Cross-subtype Immunity against Avian Influenza in Persons Recently Vaccinated for Influenza

Emerging Infectious Diseases, 2008
Avian influenza virus (H5N1) can be transmitted to humans, resulting in a severe or fatal disease. The aim of this study was to evaluate the immune cross-reactivity between human and avian influenza (H5N1) strains in healthy donors vaccinated for ...
Cristiana Gioia, Concetta Castilletti, Massimo Tempestilli, Paola Piacentini, Licia Bordi, Roberta Chiappini, Chiara Agrati, Salvatore Squarcione, Giuseppe Ippolito, Vincenzo Puro, Maria Rosaria Capobianchi, Fabrizio Poccia   +11 more
doaj   +1 more source

Molecular Epidemiology of Clade 1 Influenza A Viruses (H5N1), Southern Indochina Peninsula, 2004–2007

Emerging Infectious Diseases, 2009
To determine the origin of influenza A virus (H5N1) epizootics in Cambodia, we used maximum-likelihood and Bayesian methods to analyze the genetic sequences of subtype H5N1 strains from Cambodia and neighboring areas.
Philippe Buchy, Mathieu Fourment, Sek Mardy, San Sorn, Davun Holl, Sowath Ly, Sirenda Vong, Vincent Enouf, J.S. Malik Peiris, Silvie van der Werf   +9 more
doaj   +1 more source

Whole-genome sequence and genesis of an avian influenza virus H5N1 isolated from a healthy chicken in a live bird market in Indonesia: accumulation of mammalian adaptation markers in avian hosts [PDF]

PeerJ, 2023
Background Influenza A viruses are a major pathogen that causes significant clinical and economic harm to many animals. In Indonesia, the highly pathogenic avian influenza (HPAI) H5N1 virus has been endemic in poultry since 2003 and has caused sporadic ...
Saifur Rehman, Rima Ratnanggana Prasetya, Krisnoadi Rahardjo, Mustofa Helmi Effendi, Fedik Abdul Rantam, Jola Rahmahani, Adiana Mutamsari Witaningrum, Aldise Mareta Nastri, Jezzy Renova Dewantari, Yasuko Mori, Kazufumi Shimizu   +10 more
doaj   +2 more sources