Results 31 to 40 of about 20,121 (221)

The special neuraminidase stalk-motif responsible for increased virulence and pathogenesis of H5N1 influenza A virus. [PDF]

PLoS ONE, 2009
The variation of highly pathogenic avian influenza H5N1 virus results in gradually increased virulence in poultry, and human cases continue to accumulate.
Hongbo Zhou, Zhengjun Yu, Yong Hu, Jiagang Tu, Wei Zou, Yaping Peng, Jiping Zhu, Yongtao Li, Anding Zhang, Ziniu Yu, Zhiping Ye, Huanchun Chen, Meilin Jin   +12 more
doaj   +1 more source

Novel phylogenetic algorithm to monitor human tropism in Egyptian H5N1-HPAIV reveals evolution toward efficient human-to-human transmission [PDF]

, 2013
Years of endemic infections with highly pathogenic avian influenza (HPAI) A subtype H5N1 virus in poultry and high numbers of infections in humans provide ample opportunity in Egypt for H5N1-HPAIV to develop pandemic potential.
Ursula Dietrich (351656), Perovic, Vladimir R., Dietrich, Ursula, Veljković, Nevena V., Veljkovic, Nevena, Ursula Dietrich, Claude P. Muller (106167), Nevena Veljkovic, Henry L. Niman (407613), Dusan D Tosic, Nevena Veljkovic (338669), Veljko Veljkovic (315720), Sanja Glisic, Sanja Glisic (168160), Muller, Claude P., Dusan D. Tosic (407614), Vladimir R. Perovic (407612), Niman, Henry L., Veljkovic, Veljko, Tosic, Dusan D., Vladimir R Perovic, Claude P Muller, Veljko Veljkovic, Henry L Niman, Glisic, Sanja   +24 more
core   +1 more source

Isocyanides as Influenza A Virus Subtype H5N1 Wild‐Type M2 Channel Inhibitors

ChemMedChem, 2015
AbstractBasic bulky amines such as amantadine are well‐characterized M2 channel blockers, useful for treating influenza. Herein we report our surprising findings that charge‐neutral, bulky isocyanides exhibit activities similar to—or even higher than—that of amantadine.
Wu, Sa, b, Huang, Ja, Gazzarrini, Sc, He, Sa, Chen, La, Li, Ja, Xing, Ld, Li, Ce, Chen, Le, Neochoritis, CGf, Liao, GPf, Zhou, Ha, Dömling, Af, Moroni, Ac, Wang, W   +30 more
openaire   +3 more sources

Geographic Co-distribution of Influenza Virus Subtypes H7N9 and H5N1 in Humans, China

Emerging Infectious Diseases, 2013
To the Editor: Human infection with a novel low pathogenicity influenza A(H7N9) virus in eastern China has recently raised global public health concerns (1). The geographic sources of infection have yet to be fully clarified, and confirmed human cases from 1 province have not been linked to those from other provinces. While some studies have identified
Wang, Liya, Zhang, Wenyi, Soares Magalhaes, Ricardo J., Clements, Archie C. A., Hu, Wenbiao, Ding, Fan, Sun, Hailong, Li, Shenlong, Liu, Qiyong, Cheng, Zeliang, Sun, Yansong, Huang, Liuyu, Li, Cheng-Yi   +12 more
openaire   +6 more sources

A single dose of DNA vaccine based on conserved H5N1 subtype proteins provides protection against lethal H5N1 challenge in mice pre-exposed to H1N1 influenza virus

Virology Journal, 2010
Background Highly pathogenic avian influenza virus subtype H5N1 infects humans with a high fatality rate and has pandemic potential. Vaccination is the preferred approach for prevention of H5N1 infection.
Chang Haiyan, Huang Chaoyang, Wu Jian, Fang Fang, Zhang Wenjie, Wang Fuyan, Chen Ze   +6 more
doaj   +1 more source

Purification of neuraminidase from Influenza virus subtype H5N1

Jurnal Ilmu Ternak dan Veteriner, 2013
Influenza-virus neuraminidase plays vital role in the survival of the organisms. Vaccination of animals with this glycoprotein confers immune responses so that enable it to protect the animals from incoming infection. Supplementation of conventional vaccines with this glycoprotein increases the protection and longevity of the vaccine.
Simson Tarigan, Risa Indryani, Darminto ., Jagoda Ignjatovic   +3 more
openaire   +1 more source

Susceptibility of Canada Geese (Branta canadensis) to Highly Pathogenic Avian Influenza Virus (H5N1)

Emerging Infectious Diseases, 2007
Migratory birds have been implicated in the long-range spread of highly pathogenic avian influenza (HPAI) A virus (H5N1) from Asia to Europe and Africa.
John Pasick, Yohannes Berhane, Carissa Embury-Hyatt, John Copps, Helen Kehler, Katherine Handel, Shawn Babiuk, Kathleen Hooper-McGrevy, Yan Li, Quynh Mai Le, Song Lien Phuong   +10 more
doaj   +1 more source

A protective role for complement C3 protein during pandemic 2009 H1N1 and H5N1 influenza A virus infection. [PDF]

PLoS ONE, 2011
Highly pathogenic H5N1 influenza infections are associated with enhanced inflammatory and cytokine responses, severe lung damage, and an overall dysregulation of innate immunity.
Kevin B O'Brien, Thomas E Morrison, David Y Dundore, Mark T Heise, Stacey Schultz-Cherry   +4 more
doaj   +1 more source

Avian influenza (H5N1) virus, epidemiology and its effects on backyard poultry in Indonesia: a review [version 2; peer review: 2 approved]

F1000Research, 2023
Avian influenza (AI) is a zoonotic viral endemic disease that affects poultry, swine, and mammals, including humans. Highly pathogenic avian influenza (HPAI) is caused by influenza type A virus subtypes H5, and H7 which are naturally carried by a wild ...
Mustofa Helmi Effendi, Adiana Mutamsari Witaningruma, Rao Zahid Abbas, Kashif Hussain, Ugbo Emmanuel Nnabuikeb, Asghar Abbas, Saifur Rehman, Muhammad Bilal   +7 more
doaj   +1 more source

Influenza A H5N1 Replication Sites in Humans

Emerging Infectious Diseases, 2005
Tissue tropism and pathogenesis of influenza A virus subtype H5N1 disease in humans is not well defined. In mammalian experimental models, H5N1 influenza is a disseminated disease.
Mongkol Uiprasertkul, Pilaipan Puthavathana, Kantima Sangsiriwut, Phisanu Pooruk, Kanittar Srisook, Myoung-don Oh, John M. Nicholls, Kulkanya Chokephaibulkit, Nirun Vanprapar, Prasert Auewarakul   +9 more
doaj   +1 more source