The susceptibility of magpies to a highly pathogenic avian influenza virus subtype H5N1
Korean wild magpies (Pica pica sericea) were intranasally inoculated with highly pathogenic avian influenza (A/Chicken/Korea/ES/03 virus) (H5N1), which was classified as clade 2.5. We estimated viral replication, death after infection, and histology and immunohistochemistry.
Y K, Kwon +7 more
openaire +2 more sources
Isolation and characterization of highly pathogenic avian influenza virus subtype H5N1 from donkeys [PDF]
The highly pathogenic H5N1 is a major avian pathogen that crosses species barriers and seriously affects humans as well as some mammals. It mutates in an intensified manner and is considered a potential candidate for the possible next pandemic with all the catastrophic consequences.Nasal swabs were collected from donkeys suffered from respiratory ...
Abdel-Ghany Ahmad E +2 more
openaire +3 more sources
MVA-based H5N1 vaccine affords cross-clade protection in mice against influenza A/H5N1 viruses at low doses and after single immunization. [PDF]
Human infections with highly pathogenic avian influenza viruses of the H5N1 subtype, frequently reported since 2003, result in high morbidity and mortality.
Sutter, G. (Gerd) +50 more
core +1 more source
The special neuraminidase stalk-motif responsible for increased virulence and pathogenesis of H5N1 influenza A virus. [PDF]
The variation of highly pathogenic avian influenza H5N1 virus results in gradually increased virulence in poultry, and human cases continue to accumulate.
Hongbo Zhou +12 more
doaj +1 more source
H5N1 Clade 2.2 Polymorphism Tracing Identifies Influenza Recombination and Potential Vaccine Targets [PDF]
Highly pathogenic Influenza A H5N1 was first identified in Guangdong Province in 1996, followed by human cases in Hong Kong in 1997 1. The number of confirmed human cases now exceeds 300 and the associated Case Fatality Rate exceeds 60% 2.
Nasr M. ElSayed +26 more
core +1 more source
Isocyanides as Influenza A Virus Subtype H5N1 Wild‐Type M2 Channel Inhibitors
AbstractBasic bulky amines such as amantadine are well‐characterized M2 channel blockers, useful for treating influenza. Herein we report our surprising findings that charge‐neutral, bulky isocyanides exhibit activities similar to—or even higher than—that of amantadine.
Wu +30 more
openaire +3 more sources
Pathobiology of avian influenza in wild bird species [PDF]
Avian influenza viruses, especially highly pathogenic avian influenza viruses (HPAIV), affect a wide range of species, including humans and have thus become a major concern for veterinary medicine and public health.
Bröjer, Caroline
core +1 more source
Geographic Co-distribution of Influenza Virus Subtypes H7N9 and H5N1 in Humans, China
To the Editor: Human infection with a novel low pathogenicity influenza A(H7N9) virus in eastern China has recently raised global public health concerns (1). The geographic sources of infection have yet to be fully clarified, and confirmed human cases from 1 province have not been linked to those from other provinces. While some studies have identified
Wang, Liya +12 more
openaire +6 more sources
Novel phylogenetic algorithm to monitor human tropism in Egyptian H5N1-HPAIV reveals evolution toward efficient human-to-human transmission [PDF]
Years of endemic infections with highly pathogenic avian influenza (HPAI) A subtype H5N1 virus in poultry and high numbers of infections in humans provide ample opportunity in Egypt for H5N1-HPAIV to develop pandemic potential.
Ursula Dietrich (351656) +24 more
core +1 more source
Background Highly pathogenic avian influenza virus subtype H5N1 infects humans with a high fatality rate and has pandemic potential. Vaccination is the preferred approach for prevention of H5N1 infection.
Chang Haiyan +6 more
doaj +1 more source

